Calorie Restriction in Obesity: Prevention of Kidney Disease in Rodents

The Effect of Retarded Growth Upon the Length of Life Span and Upon the Ultimate Body Size

1935 • 2,189 citations

Overweight Children and Adolescents: Description, Epidemiology, and Demographics

1998 • 1,382 citations

Emerging epidemic of type 2 diabetes in youth.

1999 • 1,051 citations

Spontaneous long-term hyperglycemic rat with diabetic complications. Otsuka Long-Evans Tokushima Fatty (OLETF) strain

1992 • 869 citations

End-stage renal failure in type 2 diabetes: A medical catastrophe of worldwide dimensions

1999 • 796 citations

Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome

2000 • 638 citations

Treatment of hyperlipidemia reduces glomerular injury in obese Zucker rats

1988 • 413 citations

The impact of gender on the progression of chronic renal disease

1995 • 386 citations

Phenotype of fatty Due to Gln269Pro Mutation in the Leptin Receptor (Lepr)

1996 • 289 citations

The obesity epidemic in children and adults: current evidence and research issues

1999 • 256 citations

Age-dependent glomerular damage in the rat. Dissociation between glomerular injury and both glomerular hypertension and hypertrophy. Male gender as a primary risk factor.

1994 • 235 citations

The Influence of Dietary Protein Source on Longevity and Age-Related Disease Processes of Fischer Rats

1988 • 222 citations

The Hyperlipidemia of the Nephrotic Syndrome

1985 • 218 citations

Effects of food restriction on aging: separation of food intake and adiposity.

1984 • 191 citations

Substitution at Codon 269 (Glutamine → Proline) of the Leptin Receptor (OB-R) cDNA Is the Only Mutation Found in the Zucker Fatty (fa/fa) Rat

1996 • 186 citations

Dietary modulation of the progression of nephropathy in aging rats: an evaluation of the importance of protein

1989 • 154 citations

Revisiting the Role of Fat Mass in the Life Extension Induced by Caloric Restriction

1999 • 148 citations

Sex related differences in glomerular ultrafiltration and proteinuria in Munich-Wistar rats

1988 • 144 citations

Development of obesity in Zucker obese (fafa) rat in absence of hyperphagia

1980 • 144 citations

Characteristics of Diabetes, Blood Pressure, and Cardiac and Renal Complications in Otsuka Long-Evans Tokushima Fatty Rats

1997 • 129 citations

Age-related nephropathy and proteinuria in rats with intact kidneys exposed to diets with different protein content.

1989 • 105 citations

Diet, Overfeeding, and Moderate Dietary Restriction in Control Sprague-Dawley Rats: II. Effects on Age-Related Proliferative and Degenerative Lesions

1995 • 96 citations

Is caloric restriction effective in preventing diabetes mellitus in the Otsuka Long Evans Tokushima Fatty rat, a model of spontaneous non-insulin-dependent diabetes mellitus?

1995 • 93 citations

Animal Models of Obesity: Genetic Aspects

1991 • 85 citations

Rodent models of nephropathy associated with type II diabetes.

1999 • 79 citations

Longevity in obese and lean male and female rats of the Zucker strain: prevention of hyperphagia

1997 • 78 citations

Modification of polycystic kidney disease and fatty acid status by soy protein diet

2000 • 66 citations

Effect of dietary soy protein and genistein on disease progression in mice with polycystic kidney disease

1998 • 66 citations

Differential effects of dietary caloric and protein restriction in the aging rat

1983 • 63 citations

Current strategies for retarding progression of renal disease

1998 • 62 citations

Estrogen accelerates the development of renal disease in female obese Zucker rats

1998 • 60 citations

Estrogen induces glomerulosclerosis in analbuminemic rats

1998 • 57 citations

The Early Effects of Dietary Restriction on the Pathogenesis of Chronic Renal Disease in Sprague-Dawley Rats at 12 Months

1993 • 57 citations

The Effect of Restricted Food Intake on the Life Span of Genetically Obese Mice

1958 • 53 citations

Evaluation of glomerular lesion and abnormal urinary findings in OLETF rats resulting from a long-term diabetic state

1996 • 51 citations

Effects of Caloric Intake and Dietary Composition on the Development of Proteinuria, Age-Associated Renal Disease and Longevity in the Male Rat

1982 • 46 citations

Decrease in triglyceride accumulation in tissues by restricted diet and improvement of diabetes in otsuka long-evans tokushima fatty rats, a non—insulin-dependent diabetes model

2000 • 42 citations

Reduction of insulin and triglycerides delays glomerulosclerosis in obese Zucker rats

1997 • 33 citations

Brief periods of hyperphagia cause renal injury in the obese Zucker rat

1999 • 32 citations

Dietary protein and the progression of renal disease.

1983 • 29 citations

Relationship of dietary intake to the development of glomerulosclerosis in obese Zucker rats

1982 • 27 citations

Obesity is necessary but not sufficient for the development of diabetes mellitus

1996 • 26 citations

High lipid levels in very low density lipoprotein and intermediate density lipoprotein may cause proteinuria and glomerulosclerosis in aging female analbuminemic rats.

1995 • 26 citations

Effect of Low Calorie Diet on the Hyperlipidemia, Hypertension, and Life Span of Genetically Obese Rats

1976 • 23 citations

Commentary

1996 • 21 citations

Diabetic Nephropathy

1997 • 19 citations

Adolescent obesity, a need for greater awareness and improved treatment

1999 • 18 citations

Ovariectomy decreases plasma triglyceride levels and both prevents and alleviates glomerular disease in uninephrectomized female analbuminemic rats.

1996 • 17 citations

Renal hemodynamics in Otsuka Long-Evans Tokushima fatty rat, a model rat of spontaneous non-insulin-dependent diabetes mellitus with obesity

1999 • 14 citations

Diabetic nephropathy

1998 • 13 citations

A high-fat diet aggravates tubulointerstitial but not glomerular lesions in obese Zucker rats

1999 • 12 citations

Diet‐ and hormone‐induced lipid deposition in rat kidney: Correlation with systolic blood pressure

1983 • 5 citations