Substrate specificity of the ileal and the hepatic Na+/bile acid cotransporters of the rabbit. II. A reliable 3D QSAR pharmacophore model for the ileal Na+/bile acid cotransporter

The Liver: Biology and Pathobiology

1995 • 629 citations

Poling: Promoting conformational variation

1995 • 439 citations

Identification of a Mutation in the Ileal Sodium-dependent Bile Acid Transporter Gene That Abolishes Transport Activity

1995 • 221 citations

Studies on the mechanism of formation of 4-hydroxynonenal during microsomal lipid peroxidation

1986 • 173 citations

Computer‐Assisted Lead Finding and Optimization

1997 • 148 citations

Liver-specific drug targeting by coupling to bile acids.

1992 • 131 citations

Ligand-independent oligomerization of natriuretic peptide receptors. Identification of heteromeric receptors and a dominant negative mutant.

1992 • 131 citations

Substrate specificity of the ileal and the hepatic Na+/bile acid cotransporters of the rabbit. I. Transport studies with membrane vesicles and cell lines expressing the cloned transporters

1999 • 114 citations

Intestinal bile acid absorption. Na(+)-dependent bile acid transport activity in rabbit small intestine correlates with the coexpression of an integral 93-kDa and a peripheral 14-kDa bile acid-binding membrane protein along the duodenum-ileum axis.

1993 • 113 citations

Bile acid transport systems as pharmaceutical targets

1996 • 79 citations

Intestinal absorption of peptides by coupling to bile acids.

1994 • 78 citations

Properties and biological significance of the ileal bile salt transport system.

1979 • 75 citations

Bile acid transporters

1995 • 73 citations

Enhanced Transepithelial Transport of Peptides by Conjugation to Cholic Acid

1997 • 71 citations

Bile acid derived HMG-CoA reductase inhibitors

1994 • 55 citations

Effects of 2164U90 on ileal bile acid absorption and serum cholesterol in rats and mice.

1995 • 55 citations

Intestinal absorption of bile acids: paradoxical behaviour of the 14 kDa ileal lipid-binding protein in differential photoaffinity labelling

1998 • 50 citations

Characterization and chemical modification of the Na+-dependent bile-acid transport system in brush-border membrane vesicles from rabbit ileum

1992 • 50 citations

Molecular modeling of the intestinal bile acid carrier: a comparative molecular field analysis study.

1997 • 50 citations

Specific Inhibitors of Ileal Bile Acid Transport

1994 • 45 citations

Cholyl-lysylfluorescein: synthesis, biliary excretion in vivo and during single-pass perfusion of isolated perfused rat liver

1991 • 43 citations

Modified bile acids as carriers for peptides and drugs

1997 • 42 citations

Fluorescent bile acid derivatives: Relationship between chemical structure and hepatic and intestinal transport in the rat

1997 • 42 citations

Topological Photoaffinity Labeling of the Rabbit Ileal Na⁺/Bile‐Salt‐Cotransport System

1997 • 41 citations

Inhibition of ileal sodium-dependent bile acid transport by 2164U90.

1995 • 40 citations

Synthesis and Biological Activity of Bile Acid-Derived HMG-CoA Reductase Inhibitors. The Role of 21-Methyl in Recognition of HMG-CoA Reductase and the Ileal Bile Acid Transport System

1994 • 36 citations

Bile acids in liver diseases

1997 • 28 citations

Interaction of uncharged bile salt derivatives with the ileal bile salt transport system

1977 • 24 citations

Interactions of cationic bile salt derivatives with the ileal bile salt transport system.

1975 • 23 citations

Intramolecular catalysis in the acetylation of methyl cholate

1969 • 13 citations

Biliary excretion of chenodeoxycholyllsylrhodamine in Wistar rats: A possible role of a bile acid as a carrier for drugs

1992 • 8 citations

Ileal absorption of tyrosine-conjugated bile acids in Wistar rats

1987 • 7 citations

Deleted Work

1955 • 0 citations