Increased Carbon Tetrachloride Hepatotoxicity, and its Mechanism, After Chronic Ethanol Consumption

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

THE COLORIMETRIC DETERMINATION OF PHOSPHORUS

1925 • 19,115 citations

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 11,832 citations

Methods of enzymatic analysis

1964 • 5,230 citations

The colorimetric estimation of formaldehyde by means of the Hantzsch reaction

1953 • 4,357 citations

Carbon tetrachloride hepatotoxicity.

1967 • 980 citations

Serum Glutamic Pyruvic Transaminase in Cardiac and Hepatic Disease.

1956 • 811 citations

Fatty Liver in the Rat after Prolonged Intake of Ethanol with a Nutritionally Adequate New Liquid Diet

1967 • 604 citations

Necrogenic Action of Carbon Tetrachloride in the Rat: A Speculative Mechanism Based on Activation

1966 • 457 citations

A rapid chemical method for quantification of lipids separated by thin-layer chromatography

1964 • 402 citations

Hepatic Microsomal Enzymes in Man and Rat: Induction and Inhibition by Ethanol

1968 • 331 citations

The effect of diet and 1,1,1-trichloro-2,2-bis-(p-chlorophenyl)ethane (DDT) on microsomal hydroxylating enzymes and on sensitivity of rats to carbon tetrachloride poisoning

1966 • 327 citations

Quantitative Relationship between Amount of Dietary Fat and Severity of Alcoholic Fatty Liver

1970 • 313 citations

The role of the hepatic microsomal ethanol oxidizing system (MEOS) for ethanol metabolism in vivo.

1972 • 290 citations

LIVER PARENCHYMAL CELL INJURY

1963 • 288 citations

Increase of ethanol, meprobamate and pentobarbital metabolism after chronic ethanol administration in man and in rats

1971 • 263 citations

Increased susceptibility to carbon tetrachloride poisoning in the rat after pretreatment with oral phenobarbitone

1969 • 216 citations

Alterations in microsomal electron transport, oxidative N-demethylation and azo-dye cleavage in carbon tetrachloride and dimethylnitrosamine-induced liver injury

1967 • 187 citations

Diverse effects of SKF 525-A and antioxidants on carbon tetrachloride-induced changes in liver microsomal P-450 content and ethylmorphine metabolism

1968 • 174 citations

Glucose-6-phosphatase

1965 • 166 citations

The distribution of the components of mixed-function oxidase between the rough and the smooth endoplasmic reticulum of liver cells

1968 • 164 citations

The influence of phenobarbital on the turnover of hepatic microsomal cytochrome b5 and cytochrome P-450 hemes in the rat

1970 • 129 citations

Liver parenchymal cell injury. IV. Pattern of incorporation of carbon and chlorine from carbon tetrachloride into chemical constituents of liver in vivo.

1967 • 115 citations

The effect of diet on carbon tetrachloride metabolism

1967 • 112 citations

Effect of chronic ethanol feeding on the activities and submicrosomal distribution of reduced nicotinamide adenine dinucleotide phosphate-cytochrome P-450 reductase and the demethylases for aminopyrine and ethylmorphine

1973 • 110 citations

Bildung von Chloroform aus Tetrachlorkohlenstoff in Lebermikrosomen, Lipidperoxidation und Zerst�rung von Cytochrom P-450

1972 • 103 citations

The Increasing Mortality Attributed to Cirrhosis and Fatty Liver, in Baltimore (1957-1966)

1968 • 89 citations

Relationship of alcohol metabolism to the potentiation of CCl 4 hepatotoxicity induced by aliphatic alcohols.

1972 • 85 citations

Ethanol Potentiation of Halogenated Aliphatic Solvent Toxicity

1966 • 83 citations

Incorporation of radioactive-δ-aminolevulinic acid into microsomal cytochrome P450: Selective breakdown of the hemoprotein by allylisopropylacetamide and carbon tetrachloride

1972 • 79 citations

Hemoprotein catabolism during stimulation of microsomal lipid peroxidation

1972 • 69 citations

Enhanced Hepatic Microsomal Activity by Pretreatment of Rats with Acetone or Isopropanol

1973 • 67 citations

Liver parenchymal cell injury. V. Relationships between patterns of chloromethane-C 14 incorporation into constituents of liver in vivo and cellular injury.

1967 • 65 citations

The pathology of fatal carbon tetrachloride poisoning with special reference to the histogenesis of the hepatic and renal lesions.

1950 • 65 citations

Lipid peroxidation during enzymatic iodination of rat liver endoplasmic reticulum

1972 • 64 citations

On the mechanism of carbon tetrachloride toxicity—Coincidence of loss of drug-metabolizing activity with peroxidation of microsomal lipid

1972 • 53 citations

Metabolic Changes Induced by Alcohol

1971 • 46 citations

LIVER PARENCHYMAL CELL INJURY

1969 • 45 citations

The effect of carbon tetrachloride on heme components and ethylmorphine metabolism in rat liver microsomes

1969 • 38 citations

A further simplified method of ornithine carbamoyltransferase measurement

1968 • 26 citations

Carbon tetrachloride activation in liver microsomes from rats induced with 3-methylcholantrene

1973 • 22 citations

Increase of microsomal glucose-6-phosphatase activity after chronic ethanol administration

1973 • 20 citations

TREATMENT OF HOOKWORM DISEASE WITH CARBON TETRACHLORIDE*

1923 • 20 citations

Microsomal Oxidation of Ethanol and the Drug Metabolizing System. Studies in Animals and Man

1971 • 12 citations