Chemical Nature, Properties, Location, and Physiological and Pathological Variations of Modified Nucleosides in tRNAs

Codon—anticodon pairing: The wobble hypothesis

1966 • 1,961 citations

Structure of a Ribonucleic Acid

1965 • 1,370 citations

Compilation of tRNA sequences

1985 • 530 citations

RIBONUCLEIC ACIDS FROM YEAST WHICH CONTAIN A FIFTH NUCLEOTIDE

1957 • 418 citations

Minor Components in Transfer RNA: Their Characterization, Location, and Function

1972 • 411 citations

The modified nucleosides in nucleic acids

1971 • 392 citations

Pseudouridine, a Carbon-Carbon Linked Ribonucleoside in Ribonucleic Acids: Isolation, Structure, and Chemical Characteristics

1960 • 366 citations

Nucleic Acid-Protein Recognition

1977 • 343 citations

Nucleoside-5′-Phosphates from Ribonucleic Acid

1951 • 307 citations

Taurine—a Possible Neurotransmitter ?

1971 • 256 citations

Novel features in the genetic code and codon reading patterns in Neurospora crassa mitochondria based on sequences of six mitochondrial tRNAs

1980 • 248 citations

The Structures of Two Serine Transfer Ribonucleic Acids

1966 • 240 citations

Structure of the modified nucleoside Q isolated from Escherichia coli transfer ribonucleic acid. 7-(4,5-cis-Dihydroxy-1-cyclopenten-3-ylaminomethyl)-7-deazaguanosine

1975 • 219 citations

The Methylation of Nucleic Acids

1966 • 191 citations

Modified nucleosides in transfer RNA

1977 • 171 citations

Nucleotide Sequence of Three Isoaccepting Lysine tRNAs from Rabbit Liver and SV40‐Transformed Mouse Fibroblasts

1979 • 167 citations

Regulation of tRNA

1973 • 165 citations

Activity of a transfer RNA modifying enzyme during the development of Drosophila and its relationship to the su(s) locus

1973 • 163 citations

A NEW ENZYME OF RNA SYNTHESIS: RNA METHYLASE

1962 • 149 citations

Functional adaptation of tRNA population

1974 • 148 citations

Cytokinins in the Soluble RNA of Plant Tissues

1967 • 147 citations

Transfer RNA and Cell Differentiation

1970 • 140 citations

Mapping of yeast tRNAs by two‐dimensional electrophoresis on polyacrylamide gels

1975 • 136 citations

The structure of Q* nucleoside isolated from rabbit liver transfer ribonucleic acid

1976 • 131 citations

Enzymatic Modification of Transfer RNA

1971 • 118 citations

The sequence of the 3′ non-coding region of the hexon mRNA discloses a novel adenovirus gene

1981 • 116 citations

Structure of Ribonucleic Acid

1951 • 108 citations

Distribution of the modified nucleoside Q and its derivatives in animal and plant transfer RNA's

1975 • 107 citations

Effect of diet on the queuosine family of tRNAs of germ-free mice.

1980 • 106 citations

The nucleotide sequence of two silk gland alanine tRNAs: Implications for fibroin synthesis and for initiator tRNA structure

1977 • 104 citations

Functional adaptation of tRNAs to fibroin biosynthesis in the silkgland of Bombyx mori L

1970 • 99 citations

Seryl-tRNA in Mammalian Tissues: Chromatographic Differences in Brain and Liver and a Specific Response to the Codon, UGA

1970 • 93 citations

Isolation and identification of four cytokinins from wheat germ transfer ribonucleic acid

1970 • 87 citations

A SPECIFIC MODIFICATION OF LEUCYL-sRNA OF ESCHERICHIA COLI AFTER PHAGE T2 INFECTION

1964 • 87 citations

The methylation of tRNA

1976 • 84 citations

3-(3-Amino-3-carboxypropyl)uridine. Novel modified nucleoside isolated from Escherichia coli phenylalanine transfer ribonucleic acid

1974 • 84 citations

Tumour-specific phenylalanine tRNA contains two supernumerary methylated bases

1978 • 83 citations

Effect of Threonylcarbamoyl Modification (t⁶A) in Yeast tRNA^Arg_III on Codon‐Anticodon and Anticodon‐Anticodon Interactions

1981 • 83 citations

Analysis of tRNAs during the development of Drosophila

1973 • 82 citations

Isolation of N⁶-(Aminoacyl)adenosine from Yeast Ribonucleic Acid^*

1964 • 77 citations

The presence of 5,6-dihydrouridylic acid in yeast “soluble” ribonucleic acid

1965 • 76 citations

An iron-dependent modification of several transfer RNA species in Escherichia coli

1969 • 76 citations

Study of yeast mitochondrial tRNAs by two-dimensional polyacrylamide gel electrophoresis: characterization of isoaccepting species and search for imported cytoplasmic tRNAs

1977 • 72 citations

Properties of Soluble Ribonucleic Acid Methylases from Rat Liver^*

1967 • 70 citations

Three-dimensional structure of hyper-modified nucleoside Q located in the wobbling position of tRNA

1979 • 70 citations

Adaptation of iso-tRNA concentration to mRNA codon frequency in the eukaryote cell

1979 • 69 citations

Uridin-5-oxy acetic acid: A new minor constituent from E, coli valine transfer RNA I

1970 • 69 citations

The first nucleotide sequence of an organelle transfer RNA: Chloroplastic tRNAPhe

1976 • 67 citations

Alteration of valyl-sRNA during sporulation of bacillus subtilis.

1966 • 67 citations

Changes in Amount of Hypo‐Modified tRNA Having Guanine in Place of Queuine during Erythroid Differentiation of Murine Erythroleukemia Cells

1981 • 64 citations

Changes of post-transcriptional modification of wye base in tumor-specific tRNA^Phe

1982 • 63 citations

Physiologically induced changes in the property of phenylalanine tRNA in Escherichia coli

1968 • 62 citations

Specific inhibition of transfer RNA methylation and modification in tissues of mice treated with 5-fluorouracil.

1978 • 60 citations

Isolation from rat liver and sequence of a RNA fragment containing 32 nucteotides from position 5 to 36 from the 37′ end of ribosomal 18S RNA

1978 • 60 citations

Primary sequence of arginine transfer RNA from Escherichia, coli

1972 • 58 citations

5‐methyl‐2‐thiouridine: A new sulfur‐containing minor constituent from rat liver glutamic acid and lysine tRNAs

1971 • 57 citations

Alterations in SVT2 cell transfer RNAs in response to cell density and serum type

1975 • 53 citations

Pairing properties of the methylester of 5-carboxymethyl uridine in the wobble position of yeast tRNAArg3

1978 • 51 citations

In vivo decoding rules in Schizosaccharomyces pombe are at variance with in vitro data

1981 • 50 citations

Drug effects on nucleic acid modification. I. A specific effect of 5-azacytidine on mammalian transfer RNA methylation invivo

1976 • 50 citations

Differences in lysine-sRNA from spore and vegetative cells of Bacillus subtillis.

1966 • 49 citations

Alteration of the Q family of transfer RNAs in adult Drosophila melanogaster as a function of age, nutrition, and genotype

1979 • 48 citations

Cytokinin of Wheat Germ Transfer RNA: 6-(4-Hydroxy-3-methyl-butenylamino)-2-methylthio-9-β-D-ribofuranosylpurine

1969 • 48 citations

Primary structure of three leucine transfer RNAs from bean chloroplast

1980 • 47 citations

Hormonal effect on transfer ribonucleic acid methylases and on serine transfer ribonucleic acid

1970 • 47 citations

Modified Nucleosides in tRNA

1979 • 45 citations

Isoaccepting transfer ribonucleic acids in liver and brain of young and old BC3F1 mice

1972 • 44 citations

Deficiency of the Y base in a hepatoma phenylalanine tRNA

1975 • 43 citations

Isolation and characterization of peroxy-Y base from phenylalanine transfer ribonucleic acid of the plant, Lupinus luteus

1974 • 43 citations

Unusual modification patterns in the transfer ribonucleic acids of archaebacteria

1980 • 42 citations

The isolation and characterization of N-[9-(β-D-ribofuranosyl-purin-6-ylcarbamoyl] glycine from yeast transfer RNA

1970 • 42 citations

Comparison of rat liver and Walker 256 carcinosarcoma tRNAs

1979 • 41 citations

Structure of the “Peroxy-Y Base” from Liver tRNAPhe

1971 • 41 citations

The primary structure of tRNATrp from brewer's yeast

1972 • 40 citations

Studies of odd bases in yeast mitochondrial tRNA: II. Characterization of rare nucleosides

1976 • 40 citations

Nucleic Acids In Plants: Volume I

1979 • 39 citations

Transfer RNA in aging Drosophila: II. Isoacceptor patterns

1979 • 38 citations

Occurrence of trans-ribosylzeatin in Agrobacterium tumefaciens tRNA

1976 • 38 citations

Post‐transcriptional modification of tyrosine tRNA as a function of growth in Bacillus subtilis

1976 • 38 citations

Isolation and characterization of transfer RNAs from Dictyostelium discoideum during growth and development.

1977 • 37 citations

Some physical and biological properties of 4-thiouridine- and dihydrouridine-deficient tRNA from chloramphenicol-treated Escherichia coli

1973 • 35 citations

The corrected nucleotide séquence of valine tRNA from baker's yeast

1974 • 34 citations

Nucleotide sequences of two aspartic acid tRNAs from rat liver and rat ascites hepatoma.

1981 • 34 citations

Minor components in transfer RNA: The location-function relationships

1978 • 33 citations

The altered patterns of transfer RNA in SV40-infected and transformed cells

1972 • 33 citations

Analysis of Isoaccepting Transfer Ribonucleic Acid Species of Bacillus subtilis : Chromatographic Differences Between Transfer Ribonucleic Acids from Spores and Cells in Exponential Growth

1973 • 33 citations

Nucleotide Sequence of Formylmethionine tRNA from an Extreme Thermophile, Thermus thermophilus HB8

1979 • 32 citations

The Modified Nucleosides in Transfer RNA

1977 • 32 citations

Methylation of yeast tRNAAsp by enzymes from cytoplasm, chloroplasts and mitochondria of Phaseolus vulgaris

1974 • 32 citations

2′-O-Methyl ribothymidine: a component of rabbit liver lysine transfer RNA

1974 • 31 citations

Transfer ribonucleic acid deficient in N⁶-(Δ²-isopentenyl)adenosine due to mevalonic acid limitation

1971 • 31 citations

Pattern of Valine Transfer Ribonucleic Acid of Bacillus subtilis under Different Growth Conditions

1968 • 31 citations

Isolation of hydroxy-Y base from rat liver tRNA^Phe

1979 • 30 citations

Morris hepatomas : mechanisms of regulation

1978 • 30 citations

The nucleotide sequence of glutamate tRNA₄of Drosophila melanogaster

1980 • 29 citations

Functional adaptation of aminoacyl‐tRNA synthetases to fibroin biosynthesis in the silkgland of Bombyx mori L.

1975 • 29 citations

Post-Transcriptional Modifications of the Anticodon Loop Region: Alterations in Isoaccepting Species of tRNA's During Development in Bacillus subtilis

1978 • 28 citations

Unique presence of 2-methylthio-ribosylzeatin in the transfer ribonucleic acid of the bacterium Pseudomonas aeruginosa

1974 • 28 citations

Nucleotide sequence of Bombyx mori L. tRNA1Gly

1977 • 28 citations

Primary structure of bovine liver tRNATrp

1978 • 27 citations

Essais de mise en evidence d'une regulation hormonale au niveau des RNA de transfert

1970 • 27 citations

The nucleotide sequen of human tRNA^Gly(anticodon GCC)

1979 • 27 citations

Altered chromatographic properties of tRNA from chloramphenicol-treated

1969 • 27 citations

Two Species of Bacillus subtilis Tyrosine Transfer Ribonucleic Acid

1969 • 26 citations

Formation of chromatographically unique species of transfer ribonucleic acid during amino acid starvation of relaxed-control Escherichia coli

1975 • 26 citations

Isolation of 1-methylinosine and inosine from yeast soluble ribonucleic acid

1963 • 26 citations

Relation of cell type and cell density to the degree of post-transcriptional modification of tRNALys and tRNAPhe

1975 • 25 citations

A doubtful relationship between tyrosine tRNA and suppression of the vermilion mutant in Drosophila

1977 • 25 citations

Structure elucidation by high resolution mass spectrometry of a highly modified nucleoside from mammalian transfer RNA. N-[(9-.beta.-D-Ribofuranosyl-2-methylthiopurin-6-yl)carbamoyl]threonine

1979 • 25 citations

Transfer of Valine into Rabbit Haemoglobin from Various Isoaccepting Species of Valyl‐tRNA Differing in Codon Recognition

1973 • 24 citations

Complete nucleotide sequence and properties of the major species of glycine transfer RNA from wheat germ

1977 • 24 citations

Synthèse de l'acide ribonucléique et des protéines chez Bacillus subtilis, sporogène et asporogène

1962 • 24 citations

A common change of aspartyl-tRNA in polyoma- and SV40-transformed cells

1972 • 24 citations

5-(Carboxymethylaminomethyl)-2-thiouridine, a new modified nucleoside found at the first letter position of the anticodon

1981 • 23 citations

The nucleotide sequence of rat liver tRNAAsn

1978 • 23 citations

Participation of tRNA in regulation of protein biosynthesis at the translational level in eukaryotes

1979 • 23 citations

Study of tyrosine transfer ribonucleic acid modification in relation to sporulation in Bacillus subtilis

1976 • 22 citations

The nucleotide sequence of phenylalanine tRNA₂of Drosophila melanogaster: four isoacceptors with one basic sequence

1979 • 22 citations

The Primary Structure of tRNAs and Their Rare Nucleosides

1979 • 22 citations

Characterization of Lysine Transfer Ribonucleic Acid from Vegetative Cells and Spores of Bacillus subtilis

1972 • 22 citations

Primary structure of Bacillus subtilis tRNAsTyr

1980 • 21 citations

Comparison of the nucleotide sequences of chloroplast tRNAsPhe and tRNAs3Leu from spinach and bean

1980 • 21 citations

Modified nucleosides in undermethylated phenylalanine transfer RNA from Escherichia coli

1974 • 21 citations

Function of Modified Nucleosides 7-Methylguanosine, Ribothymidine, and 2-Thiomethyl- N ⁶ -(Isopentenyl)adenosine in Procaryotic Transfer Ribonucleic Acid

1979 • 21 citations

Changes in transfer ribonucleic acids of Bacillus subtilis during different growth phases

1976 • 21 citations

Unique phenylalanine transfer ribonucleic acids in relaxed control Escherichia coli: genetic origin and some functional properties

1976 • 20 citations

Structure Determination of a Modified Nucleoside Isolated from Escherichia coli Transfer Ribonucleic Acid

1976 • 20 citations

Alterations of transfer RNA during erythroid differentiation of murine virus-induced leukemia cells

1975 • 20 citations

Precursor relationship of phenylalanine transfer ribonucleic acid from Escherichia coli treated with chloramphenicol or starved for iron, methionine, or cysteine

1975 • 20 citations

Aminoacylation and methylation of tRNA as a function of age in the rat

1972 • 20 citations

Levels of 5,6-dihydrouridine in relaxed and chloramphenicol transfer ribonucleic acid

1970 • 19 citations

Formation of phenylalanine transfer RNA lacking the wye base in Vero cells during methionine starvation.

1978 • 18 citations

Chemical post-labeling methods for the base composition and sequence analysis of RNA

1973 • 18 citations

Transfer Ribonucleic Acid in KB Cells Infected with Adenovirus Type 2

1970 • 18 citations

Isoaccepting phenylalanine tRNAs from Bacillus subtilis as a function of growth conditions Differences in the content of modified nucleosides

1977 • 18 citations

Mechanism of suppression in Drosophila. VII. Correlation between disappearance of an isoacceptor of tyrosine tRNA and activation of the vermilion locus

1978 • 18 citations

Primary structure of Bombyx mori posterior silkgland tRNAPhe

1980 • 17 citations

Behavior of chloramphenicol-induced phenylalanine transfer ribonucleic acid during recovery from chloramphenicol treatment in Escherichia coli

1973 • 17 citations

Isolation and identification of ribosyl-cis-zeatin from transfer RNA of Corynebacterium fascians

1977 • 17 citations

Comparison of Lysyl-Transfer Ribonucleic Acid Species from Vegetative Cells and Spores of Bacillus subtilis by Methylated Albumin-Kieselguhr and Reversed-Phase Chromatography

1970 • 17 citations

Isolation and comparison of ribothymidine-lacking tRNAs of fetal, newborn and adult bovine tissues

1977 • 17 citations

Comparative fingerprint and composition analysis of the three forms of phosphorus-32-labeled phenylalanine tRNA from chloramphenicol-treated Escherichia coli

1974 • 17 citations

The nucleotide sequence of phenylalanine tRNA from Bacillus subtilis

1977 • 17 citations

Estrogen-induced variation of lysine transfer ribonucleic acid isoacceptors in chicken liver

1970 • 17 citations

Abundance of tRNA^Phe lacking the peroxy Y-base in mouse neuroblastoma

1976 • 17 citations

THE METHYLATION OF TRANSFER RIBONUCLEIC ACID DURING REGENERATION OF THE LIVER

1970 • 17 citations

Biological and Structural Differences between tRNAval Species Isolated from Rat Ascites Hepatoma Cells and Normal Rat Liver1

1981 • 17 citations

Methylation of an adenosine in the D-loop of specific transfer RNAs from yeast by a procaryotic tRNA (adenine-1) methyltransferase

1977 • 16 citations

Valine transfer ribonucleic acid. I. Chromatographic study of valine tRNA modifications during Bacillus subtilis growth

1967 • 16 citations

Studies on transfer RNA population during liver regeneration in the rat

1970 • 16 citations

Studies on Methyl-deficient Methionine Transfer Ribonucleic Acid from Escherichia coli

1971 • 15 citations

Lack of a specific ribose methylation at guanosine 17 in Morris hepatoma 5123D tRNASer1IGA.

1981 • 15 citations

In vivo synthesis of tRNA1Tyr and tRNA2Tyr: Differences in “early” and “late log” E. coli MRE 600

1972 • 14 citations

Alteration of tyrosine isoaccepting transfer ribonucleic acid species in wild-type and asporogenous strains of Bacillus subtilis

1975 • 14 citations

Thiomethylation of tyrosine transfer ribonucleic acid is associated with initiation of sporulation in Bacillus subtilis: effect of phosphate concentration

1981 • 14 citations

A new uridine derivative located in the anticodon of tRNA 1Gly from Bacillus subtilis

1978 • 14 citations

On the biosynthesis of 5-methoxyuridine and uridine-5-oxyacetic acid in specific procaryotic transfer RNAs

1978 • 13 citations

The nucleotide sequence of two bovine lens phenylalanine tRNAs. Possible activation of a new phenylalanine tRNA gene during differentiation of lens cells.

1980 • 13 citations

Stability of the nucleoside composition of tRNA during biological ageing of mice and mosquitoes

1974 • 13 citations

Purification and nucleoside composition of a Q∗ — Containing aspartic acid tRNA from Drosophila

1978 • 13 citations

The sequence of mitochondrial arginine tRNA (anticodon UCG) from a transplantable rat tumor, morris hepatoma 5123D

1981 • 12 citations

Reversed phase chromatography of isoaccepting tRNA's from healthy and crown gall tissues from Nicotiana tabacum

1975 • 12 citations

Chemical basis for brain-specific serine transfer RNAs.

1977 • 12 citations

ISOACCEPTOR tRNAs FOR GLUTAMATE, GLUTAMINE, ASPARTATE AND ASPARAGINE IN CALF BRAIN

1974 • 12 citations

The distribution of modified nucleosides in transfer RNAs

1973 • 12 citations

Isoaccepting transfer rna species in differing morphogenetic states of Rhodopseudomonas spheroides

1971 • 11 citations

S-adenosylmethionine and tetrahydrofolate-dependent methylation of tRNA in Bacillus subtilis

1976 • 11 citations

Modified bases in tRNA of Dictyostelium discoideum: Alterations in the ribothymidine content during development

1977 • 11 citations

Transfer RNA specificity in mammalian tissues and codon responses of seryl transfer RNA.

1971 • 11 citations

Inhibition of RNA methylation by intercalating agents.

1977 • 11 citations

Invivo maturation of an undermodified Escherichiacoli leucine transfer RNA

1976 • 11 citations

The Presence of N-[(9-β-D-Ribofuranosyl-2-methylthiopurin-6-yl)carbamoyl]threonine in Lysine tRNA1 from Bacillus subtilis1

1981 • 11 citations

Tumor mitochondrial transfer ribonucleic acids: the nucleotide sequence of Morris hepatoma 5123D mitochondrial tRNA Asp

1981 • 10 citations

Base composition studies on transfer RNA from normal and regenerating rat liver

1978 • 10 citations

Tumor mitochondrial transfer RNAS: The nucleotide sequence of mitochondrial tRNALeuUAG from morris hepatoma 5123D

1981 • 10 citations

Reduced Aminoacylation of Asparagine-Transfer RNA Early in the Developmental Cycle ofDictyostelium discoideum:Modification Pattern and Possible Significance of the Uncharged Isoacceptor tRNA₃^Asn

1981 • 10 citations

Transfer RNA changes in HeLa cells after vaccinia virus infection

1971 • 8 citations

Identification of two lysine tRNA cistrons in Bacillus subtilis by hybridization of lysyl-tRNA with DNA

1971 • 8 citations

Mitochondrial Protein‐Synthesizing Machinery in Saccharomyces cerevisiae Grown in Different Metabolic Conditions

1979 • 8 citations

An analysis of Q and Q∗ containing tRNAs during the development of Lucilia sericata, Musca domestica and Tenebrio molitor

1979 • 8 citations

Pseudouridine Deficiency in Transfer Ribonucleic Acids from Escherichia coli Treated with 2-Thiouracil

1973 • 8 citations

Increased isoleucine acceptance by sulfur-deficient transfer RNA from Escherichia coli

1976 • 6 citations

Chromatographic separation of two ionic strength dependent conformations of valine transfer ribonucleic acid of Bacillus subtilis

1973 • 6 citations

The methylation of tRNA in KB cells after treatment with actinomycin D

1973 • 5 citations

Undermethylated transfer ribonucleic acid from a relaxed strain of Bacillus subtilis: construction of the strain and analysis of the transfer ribonucleic acid

1976 • 4 citations

NATURAL MODIFIED NUCLEOSIDES AND CHEMICAL CARCINOGENESIS: L‐ETHIONINE‐DEPENDENT INHIBITION OF N⁶‐DIMETHYLADENOSINE AND 5‐METHYLCYTIDINE SYNTHESIS ON THE tRNA LEVEL IN VIVO

1975 • 4 citations

5-(Carboxy-hydroxymethyl)uridine, a new modified nucleoside located in the anticodon of tRNA2Gly from the posterior silk glands of Bombyx mori.

1979 • 4 citations

Valine transfer RNA

1970 • 4 citations

Transfer RNA in Hepatomas

1978 • 3 citations

ChemInform Abstract: STRUCTURE ELUCIDATION BY HIGH RESOLUTION MASS SPECTROMETRY OF A HIGHLY MODIFIED NUCLEOSIDE FROM MAMMALIAN TRANSFER RNA. N‐((9‐β‐D‐RIBOFURANOSYL‐2‐METHYLTHIOPURIN‐6‐YL)CARBAMOYL)THREONINE

1979 • 2 citations