Cyclic AMP in prokaryotes.

Compilation and analysis ofEscherichia colipromoter DNA sequences

1983 • 2,228 citations

The locus of sequence-directed and protein-induced DNA bending

1984 • 1,453 citations

Regulation of cellulose synthesis in Acetobacter xylinum by cyclic diguanylic acid

1987 • 997 citations

Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells.

1982 • 929 citations

Linkage map of Escherichia coli K-12, edition 8

1990 • 764 citations

大腸菌K‐12のリンケージマップ,8版

1990 • 656 citations

Cyclic AMP Receptor Protein: Role in Transcription Activation

1984 • 645 citations

A large family of bacterial activator proteins.

1988 • 559 citations

Expression of sigma 54 (ntrA)-dependent genes is probably united by a common mechanism

1989 • 504 citations

Structure of a complex of catabolite gene activator protein and cyclic AMP refined at 2.5 Å resolution

1987 • 478 citations

Two-component regulatory systems responsive to environmental stimuli share strongly conserved domains with the nitrogen assimilation regulatory genes ntrB and ntrC.

1986 • 464 citations

Secretion of cyclolysin, the calmodulin-sensitive adenylate cyclase-haemolysin bifunctional protein of Bordetella pertussis.

1988 • 436 citations

Salmonella typhimurium deletion mutants lacking adenylate cyclase and cyclic AMP receptor protein are avirulent and immunogenic

1987 • 434 citations

Mechanism of Activation of Catabolite-Sensitive Genes: A Positive Control System

1970 • 430 citations

Transcriptional analysis of the flagellar regulon of Salmonella typhimurium

1990 • 403 citations

Nitrate respiration in relation to facultative metabolism in enterobacteria

1988 • 381 citations

AppppA, heat-shock stress, and cell oxidation.

1983 • 379 citations

Bending of DNA by gene-regulatory proteins: construction and use of a DNA bending vector

1989 • 375 citations

Selection of DNA binding sites by regulatory proteins

1988 • 364 citations

Synthetic curved DNA sequences can act as transcriptional activators in Escherichia coli.

1989 • 356 citations

GENETIC BASIS OF STARVATION SURVIVAL IN NONDIFFERENTIATING BACTERIA

1989 • 341 citations

Cyclic AMP Receptor Protein of E. coli: Its Role in the Synthesis of Inducible Enzymes

1970 • 332 citations

The DNA binding domain and bending angle of E. coli CAP protein

1986 • 322 citations

Interaction of the Escherichia coli HU protein with DNA

1986 • 321 citations

The calmodulin‐sensitive adenylate cyclase of Bordetella pertussis: cloning and expression in Escherichia col

1988 • 317 citations

AppppA and related adenylylated nucleotides are synthesized as a consequence of oxidation stress

1984 • 303 citations

Changes in the linking number of supercoiled DNA accompany growth transitions in Escherichia coli

1987 • 290 citations

Molecular cloning and nucleotide sequencing of the gene for E. coli cAMP receptor protein

1982 • 283 citations

BACTERIAL REGULATION: GLOBAL REGULATORY NETWORKS

1984 • 279 citations

Starvation-induced cross protection against osmotic challenge in Escherichia coli

1990 • 270 citations

Stringent spacing requirements for transcription activation by CRP

1990 • 265 citations

Protein phosphorylation and allosteric control of inducer exclusion and catabolite repression by the bacterial phosphoenolpyruvate: sugar phosphotransferase system

1989 • 258 citations

DNA supercoiling and the anaerobic and growth phase regulation of tonB gene expression

1988 • 257 citations

DNA supercoiling promotes formation of a bent repression loop in lac DNA

1987 • 252 citations

DNA Looping and Unlooping by AraC Protein

1990 • 247 citations

Proteins induced by aerobiosis in Escherichia coli

1983 • 244 citations

Bordetella parapertussis and Bordetella bronchiseptica contain transcriptionally silent pertussis toxin genes

1987 • 234 citations

Regulation of transcription of katE and katF in Escherichia coli

1990 • 229 citations

fixK, a gene homologous with fnr and crp from Escherichia coli, regulates nitrogen fixation genes both positively and negatively in Rhizobium meliloti.

1989 • 219 citations

Expression of glnA in Escherichia coli is regulated at tandem promoters.

1985 • 215 citations

Inhibitors of receptor-mediated endocytosis block the entry of Bacillus anthracis adenylate cyclase toxin but not that of Bordetella pertussis adenylate cyclase toxin

1988 • 210 citations

Purification of and Properties of the Cyclic Adenosine 3',5'-Monophosphate Receptor Protein which Mediates Cyclic Adenosine 3',5'-Monophosphate-dependent Gene Transcription in Escherichia coli

1971 • 210 citations

Application of fluorescence energy transfer and polarization to monitor Escherichia coli cAMP receptor protein and lac promoter interaction.

1990 • 202 citations

Homology between CAP and Fnr, a regulator of anaerobic respiration in Escherichia coli

1983 • 202 citations

Nucleotide sequence encoding the flavoprotein and hydrophobic subunits of the succinate dehydrogenase of Escherichia coli

1984 • 197 citations

Autoregulation of the Escherichia coli crp gene: CRP is a transcriptional repressor for its own gene

1983 • 191 citations

Fur (ferric uptake regulation) protein and CAP (catabolite‐activator protein) modulate transcription of fur gene in Escherichia coli

1988 • 190 citations

Protein Phosphorylation in Prokaryotes

1988 • 188 citations

Families of bacterial signal‐transducing proteins

1989 • 185 citations

Consensus DNA site for theEscherichia colicatabolite gene activator protein (CAP): CAP exhibits a 450-fold higher affinity for the consensus DNA site than for theE.coli lacDNA site

1989 • 178 citations

Cloning and sequence of the crp gene of Escherichia coli K 12

1982 • 178 citations

Mutations that alter the ability of theEscherichia colicyclic AMP receptor protein to activate transcription

1990 • 174 citations

Molecular cloning of pectate lyase genes from Erwinia chrysanthemi and their expression in Escherichia coli

1984 • 173 citations

Positive control and autogenous regulation of the nifLA promoter in Klebsiella pneumoniae

1983 • 173 citations

Bacillus anthracis calmodulin-dependent adenylate cyclase: chemical and enzymatic properties and interactions with eucaryotic cells.

1984 • 165 citations

Global control in Salmonella typhimurium: two-dimensional electrophoretic analysis of starvation-, anaerobiosis-, and heat shock-inducible proteins

1986 • 158 citations

Bordetella pertussis adenylate cyclase toxin and hemolytic activities require a second gene, cyaC, for activation

1991 • 154 citations

Adenosine 3',5'-phosphate in fungi

1981 • 150 citations

Translational efficiency of the Escherichia coli adenylate cyclase gene: mutating the UUG initiation codon to GUG or AUG results in increased gene expression.

1985 • 143 citations

Helical phase dependent action of CRP: effect of the distance between the CRP site and the −35 region on promoter activity

1990 • 142 citations

Regulation and Over-expression of the fnr Gene of Escherichia coli

1987 • 138 citations

Flagellar transcriptional activators FlbB and FlaI: gene sequences and 5' consensus sequences of operons under FlbB and FlaI control

1988 • 137 citations

DNA dynamic flexibility and protein recognition: Differential stimulation by bacterial histone-like protein HU

1988 • 133 citations

Control of Vibrio fischeri lux gene transcription by a cyclic AMP receptor protein-luxR protein regulatory circuit

1988 • 130 citations

Cyclic nucleotides in procaryotes

1981 • 130 citations

The ptsH, ptsI, and crr genes of the Escherichia coli phosphoenolpyruvate-dependent phosphotransferase system: a complex operon with several modes of transcription

1988 • 129 citations

Oxygen, nitrate, and molybdenum regulation of dmsABC gene expression in Escherichia coli

1989 • 128 citations

Lac repressor is a transient gene-activating protein

1987 • 123 citations

Escherichia coli cAMP receptor protein: evidence for three protein conformational states with different promoter binding affinities

1989 • 120 citations

Putting it on and taking it off: Phosphoprotein phosphatase involvement in cell cycle regulation

1989 • 119 citations

Adenylate cyclase toxin from Bordetella pertussis

1989 • 118 citations

Differential regulation by cyclic AMP of starvation protein synthesis in Escherichia coli

1988 • 118 citations

Cyclic diguanylic acid and cellulose synthesis in Agrobacterium tumefaciens

1989 • 117 citations

Control of Vibrio fischeri luminescence gene expression in Escherichia coli by cyclic AMP and cyclic AMP receptor protein

1985 • 117 citations

The Current Status of Cyclic Amp in Higher Plants

1977 • 117 citations

Sites of allosteric shift in the structure of the cyclic AMP receptor protein

1985 • 114 citations

SOS-independent coupling between DNA replication and cell division in Escherichia coli

1986 • 112 citations

Adenylate Cyclase Toxins from Bacillus anthracis and Bordetella pertussis

1989 • 112 citations

Synergy between Escherichia coli CAP protein and RNA polymerase in the lac promoter open complex

1989 • 110 citations

A bacterial calcium-binding protein homologous to calmodulin

1987 • 108 citations

Transcription of the Escherichia coli adenylate cyclase gene is negatively regulated by cAMP-cAMP receptor protein.

1985 • 107 citations

Identification of residues essential for catalysis and binding of calmodulin in Bordetella pertussis adenylate cyclase by site-directed mutagenesis.

1989 • 106 citations

Positive regulation of pertussis toxin expression.

1988 • 101 citations

A Xanthomonas campestris pv. campestris protein similar to catabolite activation factor is involved in regulation of phytopathogenicity

1990 • 99 citations

Genetic regulation of glycogen biosynthesis in Escherichia coli: in vitro effects of cyclic AMP and guanosine 5'-diphosphate 3'-diphosphate and analysis of in vivo transcripts

1989 • 97 citations

Structural homology between virulence-associated bacterial adenylate cyclases

1988 • 96 citations

Characterization of the Calmodulin-binding and of the Catalytic Domains of Bordetella pertussis Adenylate Cyclase

1989 • 93 citations

Activation of the lac Operon of Escherichia coli by a mutant FNR protein

1987 • 92 citations

Primary sequence of the Escherichia coli fadBA operon, encoding the fatty acid-oxidizing multienzyme complex, indicates a high degree of homology to eucaryotic enzymes

1990 • 91 citations

Multiple antibiotics produced by Pseudomonas fluorescens HV37a and their differential regulation by glucose

1986 • 91 citations

Role of the nac gene product in the nitrogen regulation of some NTR-regulated operons of Klebsiella aerogenes

1990 • 91 citations

Nucleotide sequence of the Bacillus anthracis edema factor gene (cya): a calmodulin-dependent adenylate cyclase

1988 • 91 citations

Properties of adenyl cyclase and cyclic adenosine 3',5'-monophosphate receptor protein-deficient mutants of Escherichia coli

1976 • 90 citations

An apaH mutation causes AppppA to accumulate and affects motility and catabolite repression in Escherichia coli.

1989 • 90 citations

A complex nucleoprotein structure involved in activation of transcription of two divergent Escherichia coli promoters

1989 • 90 citations

Invasive adenylate cyclase toxin of Bordetella pertussis

1989 • 90 citations

Bordetella pertussis adenylate cyclase: purification and characterization of the toxic form of the enzyme.

1989 • 89 citations

A promoter of pBR322 activated by cAMP receptor protein

1981 • 89 citations

Regulation of adenylate cyclase synthesis in Escherichia coli: nucleotide sequence of the control region.

1983 • 89 citations

Upstream activating sequences that are shared by two divergently transcribed operons mediate cAMP‐CRP regulation of pilus‐adhesin in Escherichia coli

1989 • 89 citations

DNA Bending Induced by the Catabolite Activator Protein Allows Ring Formation of a 144 bp DNA

1987 • 88 citations

Structure-function analysis of three cAMP-independent forms of the cAMP receptor protein.

1986 • 87 citations

Structural similarities between the development-specific protein S from a gram-negative bacterium, Myxococcus xanthus, and calmodulin.

1983 • 86 citations

Mechanism for the autogenous control of the crp operon: transcriptional inhibition by a divergent RNA transcript.

1986 • 86 citations

Comparative gel electrophoresis measurement of the DNA bend angle induced by the catabolite activator protein

1990 • 86 citations

Avirulent Salmonella typhimurium Δcya Δcrp oral vaccine strains expressing a streptococcal colonization and virulence antigen

1988 • 86 citations

Cyclic AMP synthesis in Escherichia coli strains bearing known deletions in the pts phosphotransferase operon

1990 • 86 citations

Mutations that alter the allosteric nature of cAMP receptor protein of Escherichia coli.

1985 • 85 citations

Transcription of the Escherichia coli fumarate reductase genes (frdABCD) and their coordinate regulation by oxygen, nitrate, and fumarate

1985 • 84 citations

Adenosine 3′:5′-Cyclic Monophosphate Control of the Enzymes of Glutamine Metabolism in Escherichia coli

1972 • 83 citations

Cloning and expression of the calmodulin-sensitive Bacillus anthracis adenylate cyclase in Escherichia coli

1988 • 83 citations

Regulation of luminescence by cyclic AMP in cya-like and crp-like mutants of Vibrio fischeri

1989 • 83 citations

Cyclic AMP-dependent initiation and rho-dependent termination of colicin E1 gene transcription.

1983 • 82 citations

Bordetella pertussis adenylate cyclase

1988 • 81 citations

Analysis of the Escherichia coli gene encoding L-asparaginase II, ansB, and its regulation by cyclic AMP receptor and FNR proteins

1990 • 79 citations

Co-operative interactions between the catabolite gene activator protein and the lac repressor at the lactose promoter

1990 • 78 citations

Cooperative DNA binding of heterologous proteins: evidence for contact between the cyclic AMP receptor protein and RNA polymerase.

1988 • 78 citations

Nucleotide sequence of the ilvB promoter-regulatory region: a biosynthetic operon controlled by attenuation and cyclic AMP.

1982 • 77 citations

Bacillus subtilis citB gene is regulated synergistically by glucose and glutamine

1985 • 77 citations

Nucleotide sequences of fic and fic-1 genes involved in cell filamentation induced by cyclic AMP in Escherichia coli

1989 • 76 citations

Variations of intramolecular ligation rates allow the detection of protein-induced bends in DNA.

1986 • 74 citations

The acid phosphatase with optimum pH of 2.5 of Escherichia coli. Physiological and Biochemical study.

1982 • 74 citations

Ligand-modulated binding of a gene regulatory protein to DNA

1989 • 72 citations

On the role of cyclic AMP and the Fnr protein in Escherichia coli growing anaerobically

1987 • 71 citations

The complete nucleotide sequence of the adenylate cyclase gene ofEscherichia coli

1984 • 71 citations

Cyclic AMP-cyclic AMP receptor protein as a repressor of transcription of the spf gene of Escherichia coli

1988 • 70 citations

Stable DNA Loops in Vivo and in Vitro: Roles in Gene Regulation at a Distance and in Biophysical Characterization of DNA

1990 • 70 citations

tRNA(Trp) translation of leader peptide codon 12 and other factors that regulate expression of the tryptophanase operon

1990 • 69 citations

Regulation of fatty acid degradation in Escherichia coli: analysis by operon fusion

1981 • 69 citations

Overlapping and separate controls on the phosphate regulon in Escherichia coli K12

1983 • 68 citations

Isolation of Erwinia chrysanthemi kduD mutants altered in pectin degradation

1986 • 67 citations

Cellular levels, excretion, and synthesis rates of cyclic AMP in Escherichia coli grown in continuous culture

1982 • 67 citations

The cyclic 3′,5′-adenosine monophosphate receptor protein and regulation of cyclic 3′,5′-adenosine monophosphate synthesis in Escherichia coli

1978 • 67 citations

The adenylate cyclase/protein kinase cascade regulates entry into meiosis in Saccharomyces cerevisiae through the gene IME1.

1990 • 67 citations

Molecular cloning and expression of the Bacillus anthracis edema factor toxin gene: a calmodulin-dependent adenylate cyclase

1988 • 66 citations

Regulation of synthesis of a major outer membrane protein: cyclic AMP represses Escherichia coli protein III synthesis.

1979 • 64 citations

Interactions of cAMP receptor protein with the ompA gene, a gene for a major outer membrane protein of Escherichia coli

1981 • 64 citations

Use of a wild-type gene fusion to determine the influence of environmental conditions on expression of the S fimbrial adhesin in an Escherichia coli pathogen

1990 • 64 citations

Isolation and sequence analysis of the gene (cpdB) encoding periplasmic 2',3'-cyclic phosphodiesterase

1986 • 63 citations

Evidence for negative control of cya transcription by cAMP and cAMP receptor protein in intact Escherichia coli cells.

1985 • 62 citations

The nucleotide sequence of the bacteriocin promoters of plasmids Clo DF13 and Col El: role of lexA repressor and cAMP in the regulation of promoter activity

1982 • 62 citations

Artefactual Origins of Cyclic AMP in Higher Plant Tissues

1989 • 62 citations

Supercoiling facilitates lac operator-repressor-pseudooperator interactions.

1987 • 60 citations

Tandem CRP binding sites in the deo operon of Escherichia coli K-12.

1982 • 60 citations

Identification and characterization of starvation-regulated genetic loci in Salmonella typhimurium by using Mu d-directed lacZ operon fusions

1988 • 59 citations

Mutants of the catabolite activator protein of Escherichia coli that are specifically deficient in the gene-activation function.

1987 • 58 citations

Regulation of genes coding for enzyme constituents of the bacterial phosphotransferase system

1980 • 55 citations

The native form of FtsA, a septal protein of Escherichia coli, is located in the cytoplasmic membrane

1990 • 54 citations

Cyclic AMP-induced conformational change of cyclic AMP receptor protein (CRP): intragenic suppressors of cyclic AMP-independent CRP mutations

1988 • 53 citations

A novel role for cAMP in the control of the activity of the E. coli chromosome replication initiator protein, DnaA

1988 • 52 citations

Involvement of cyclic AMP and its receptor protein in filamentation of an Escherichia coli fic mutant

1982 • 51 citations

Pseudocatabolite repression of type 1 fimbriae of Escherichia coli

1982 • 50 citations

Temporal control of colicin E1 induction

1987 • 49 citations

Glutamine synthetase II inRhizobium: Reexamination of the proposed horizontal transfer of DNA from eukaryotes to prokaryotes

1989 • 49 citations

Effects of anaerobic regulatory mutations and catabolite repression on regulation of hydrogen metabolism and hydrogenase isoenzyme composition in Salmonella typhimurium

1986 • 48 citations

Identification of a second gene involved in global regulation of fumarate reductase and other nitrate-controlled genes for anaerobic respiration in Escherichia coli

1989 • 48 citations

Metabolic alterations mediated by 2-ketobutyrate in Escherichia coli K12

1984 • 48 citations

Regulation of transcription of the Escherichia coli phosphoenolpyruvate carboxykinase locus: studies with pck-lacZ operon fusions

1984 • 47 citations

Signal transduction in chemotaxis to oxygen in Escherichia coli and Salmonella typhimurium

1988 • 46 citations

Cloning and in vivo and in vitro regulation of cyclic AMP-dependent carbon starvation genes from Escherichia coli

1990 • 46 citations

Negative regulation of adenylate cyclase gene (cya) expression by cyclic AMP-cyclic AMP receptor protein in Escherichia coli: studies with cya-lac protein and operon fusion plasmids

1985 • 46 citations

Rhizobium meliloti adenylate cyclase is related to eucaryotic adenylate and guanylate cyclases

1990 • 45 citations

Calmodulin-like protein from Bacillussubtilis

1986 • 44 citations

Cellulase biosynthesis in a catabolite repression-resistant mutant of Thermomonospora curvata

1984 • 44 citations

Two catabolite activator protein molecules bind to the galactose promoter region of Escherichia coli in the presence of RNA polymerase

1983 • 44 citations

Regulation of expression of the crp gene of Escherichia coli K-12: in vivo study

1985 • 44 citations

Protein H encoded by plasmid CloDF13 is involved in excretion of cloacin DF13

1982 • 43 citations

Cyclic AMP levels during induction and repression of cellulase biosynthesis in Thermomonospora curvata

1984 • 43 citations

Calmodulin-like activity in the soluble fraction of

1981 • 42 citations

Rapid change in cyclic 3?,5?-AMP concentration triggered by a light-off or light-on signal in Anabaena cylindrica

1988 • 42 citations

Metabolism of Some Polyols byRhizobium meliloti

1970 • 42 citations

Cyclic AMP and cell division in Escherichia coli

1988 • 41 citations

Effect of cyclic guanosine 3',5'-monophosphate on nitrogen fixation in Rhizobium japonicum

1979 • 40 citations

Modulation of the stability of a gene-regulatory protein dimer by DNA and cAMP.

1989 • 39 citations

Positive regulation of the pts operon of Escherichia coli: genetic evidence for a signal transduction mechanism

1991 • 39 citations

Transcription from the Escherichia coli melR promoter is dependent on the cyclic AMP receptor protein

1988 • 39 citations

Binding of CRP to DNA-dependent RNA polymerase from E. coli: Modulation by cAMP of the interactions with free and DNA-bound holo and core enzyme

1980 • 37 citations

Binding of the cyclic AMP receptor protein of Escherichia coli to RNA polymerase

1988 • 37 citations

Uptake of Cyclic AMP by Natural Populations of Marine Bacteria

1982 • 36 citations

The CytR repressor antagonizes cyclic AMP-cyclic AMP receptor protein activation of the deoCp2 promoter of Escherichia coli K-12

1990 • 36 citations

Physiological consequences of the complete loss of phosphoryl-transfer proteins HPr and FPr of the phosphoenolpyruvate:sugar phosphotransferase system and analysis of fructose (fru) operon expression in Salmonella typhimurium

1990 • 36 citations

Reconstitution of regulatory properties of adenylate cyclase in Escherichia coli extracts.

1985 • 36 citations

Sequence-dependent contribution of distal binding domains to CAP protein-DNA binding affinity

1991 • 35 citations

The catabolite-sensitive promoter for the chloramphenicol acetyl transferase gene is preceded by two binding sites for the catabolite gene activator protein

1982 • 35 citations

Activation of the lac promoter and its variants

1989 • 34 citations

Catabolite Effects On Enzyme Induction And Substrate Utilization In Rhizobium leguminosarum

1983 • 34 citations

Repression and catabolite gene activation in the araBAD operon

1987 • 34 citations

Double negative and positive control of tsx expression in Escherichia coli

1988 • 33 citations

Bordetella pertussis adenylate cyclase. Identification of multiple forms of the enzyme by antibodies.

1988 • 33 citations

Evidence in vivo for autogenous control of the cyclic AMP receptor protein gene (crp) in Escherichia coli by divergent RNA

1988 • 32 citations

crp genes of Shigella flexneri, Salmonella typhimurium, and Escherichia coli

1986 • 32 citations

Promoter mutation causing catabolite repression of the Salmonella typhimurium leucine operon

1984 • 32 citations

CRP/cAMP‐ and CytR‐regulated promoters in Escherichia coli K12: the cdd promoter

1989 • 32 citations

Regulation of adenylate cyclase synthesis in Escherichia coli: studies with cya-lac operon and protein fusion strains

1982 • 31 citations

Involvement of the histidine protein (HPr) of the phosphotransferase system in chemotactic signaling of Escherichia coli K-12

1990 • 31 citations

Tandem DNA‐bound cAMP‐CRP complexes are required for transcriptional repression of the deoP2 promoter by the CytR repressor in Escherichia coli

1990 • 31 citations

Molecular mechanisms of bacterial chemotaxis towards PTS-carbohydrates

1989 • 31 citations

Aspects of the Regulation of Adenylate Cyclase Synthesis in Escherichia coli K12

1988 • 31 citations

Cloning and characterization of the aerobic sn-glycerol-3-phosphate dehydrogenase structural gene glpD of Escherichia coli K-12

1987 • 30 citations

Design of camp?CRP-activated promoters in Escherichia coli

1991 • 30 citations

Evidence for the presence of cyclic adenosine monophosphate inBacillus subtilis

1984 • 30 citations

Cyclic-AMP-dependent switch in initiation of transcription from the two promoters of the Escherichia coli gal operon: identification and assay of 5'-triphosphate ends of mRNA by GTP:RNA guanyltransferase

1989 • 30 citations

The invasive adenylate cyclase of Bordetella pertussis. Properties and penetration kinetics

1987 • 30 citations

Regulation of hutUH operon expression by the catabolite gene activator protein-cyclic AMP complex in Klebsiella aerogenes

1984 • 29 citations

Catabolite repression of Escherichia coli heat-stable enterotoxin activity

1981 • 29 citations

Mechanism of CRP-mediated cya suppression in Escherichia coli

1983 • 29 citations

Cyclic AMP and anaerobic gene expression in E. coli

1984 • 28 citations

Isolation of a novel calcium‐binding protein from streptomyces erythreus

1984 • 28 citations

Characterization of the bacterial cell associated calmodulin-sensitive adenylate cyclase from Bordetella pertussis

1989 • 28 citations

Cloning and expression of mouse-brain calmodulin as an activator of Bordetella pertussis adenylate cyclase in Escherichia coli

1989 • 27 citations

Properties of cyclic AMP-independent catabolite gene activator proteins of Escherichia coli.

1986 • 26 citations

Studies on deo operon regulation in Escherichia coli: cloning and expression of the deoR structural gene

1984 • 26 citations

Catabolite repression in Streptomyces venezuelae. Induction of β-galactosidase, chloramphenicol production, and intracellular cyclic adenosine 3′,5′-monophosphate concentrations

1982 • 26 citations

Negative control of orinithine decarboxylase and arginine decarboxylase by adenosine-3′:5′-Cyclic monophosphate in Escherichia coli

1982 • 26 citations

Regulation of ubiG gene expression in Escherichia coli

1988 • 26 citations

Cyclic 3′5′-adenosine monophosphate synthesis in Rhizobium: Identification of a cloned sequence from Rhizobium meliloti coding for adenyl cyclase

1983 • 25 citations

pH‐regulated gene expression in Salmonella: genetic analysis of aniG and cloning of the earA regulator

1989 • 25 citations

Regulation of Escherichia coli -asparaginase II and -aspartase by the fnr gene-product

1987 • 25 citations

Adenylate cyclase is required for chemotaxis to phosphotransferase system sugars by Escherichia coli

1983 • 24 citations

Transcriptional terminator is a positive regulatory element in the expression of the Escherichia coli crp gene

1991 • 24 citations

Transcription and regulation of the cpdB gene in Escherichia coli K12 and Salmonella typhimurium LT2: Evidence for modulation of constitutive promoters by cyclic AMP-CRP complex

1990 • 24 citations

Site-directed mutagenesis of lysine 58 in a putative ATP-binding domain of the calmodulin-sensitive adenylate cyclase from Bordetella pertussis abolishes catalytic activity

1989 • 23 citations

Cyclic AMP inhibits developmental regulation of Chlamydia trachomatis

1986 • 23 citations

Investigation of the cAMP receptor protein secondary structure by Raman spectroscopy

1990 • 23 citations

Positive regulation of gene expression by cyclic AMP and its receptor protein in Escherichia coli.

1987 • 22 citations

Indirect role of adenylate cyclase and cyclic AMP in chemotaxis to phosphotransferase system carbohydrates in Escherichia coli K-12

1987 • 22 citations

Analysis of protein expression in response to osmotic stress inEscherichia coli

1990 • 22 citations

Isolation and expression of the Bradyrhizobium japonicum adenylate cyclase gene (cya) in Escherichia coli

1984 • 22 citations

The invasive adenylate cyclase of Bordetella pertussis. Intracellular localization and kinetics of penetration into various cells

1987 • 21 citations

A new DNA binding mode for CAP.

1990 • 21 citations

Characterization of Escherichia coli adenylate cyclase mutants with modified regulation

1990 • 21 citations

Arginine substituted for leucine at position 195 produces a cyclic AMP-independent form of the Escherichia coli cyclic AMP receptor protein.

1988 • 21 citations

Positive regulation of the colicin E1 gene by cyclic AMP and cyclic AMP receptor protein

1985 • 21 citations

Mechanisms of bacterial pathogenicity that involve production of calmodulin-sensitive adenylate cyclases

1987 • 21 citations

Isolation and characterization of lac fusions to two nitrogen-regulated promoters

1984 • 20 citations

Cyclic AMP phosphodiesterase in Salmonella typhimurium: characteristics and physiological function

1984 • 20 citations

Regulation of H2 oxidation activity and hydrogenase protein levels by H2, O2, and carbon substrates in Alcaligenes latus

1987 • 20 citations

Divergent effects of cyclic adenosine 3',5'-monophosphate on formation of type 1 fimbriae in different K-12 strains of Escherichia coli

1981 • 20 citations

Catabolite repression and role of cyclic AMP in CO2 fixation and H2 metabolism in Rhizobium spp

1985 • 20 citations

The in vitro expression of the gene for Escherichia coli ADP glucose pyrophosphorylase is stimulated by cyclic AMP and cyclic AMP receptor protein.

1983 • 20 citations

Structure?Function Relationships in Escherichia coli Promoter DNA

1990 • 19 citations

The Effect of Growth Conditions on Adenylate Cyclase Activity and Virulence-related Properties of Bordetella pertussis

1985 • 19 citations

Adenylate cyclase activity in Cyanobacteria: activation by Ca2+-calmodulin and a calmodulin-like activity

1990 • 19 citations

Evidence for the Presence of cAMP, cAMP Receptor and Transcription Termination Factor Rho in Different Gram-negative Bacteria

1985 • 19 citations

Morphological transformation of Chinese hamster cells by acylpeptides, inhibitors of cAMP phosphodiesterase, produced by Bacillus subtilis.

1985 • 19 citations

Regulation of a cya-lac fusion by cyclic AMP in Salmonella typhimurium

1985 • 18 citations

Regulation ofEscherichia colil-asparaginase II and l-aspartase by thefnrgene-product

1987 • 18 citations

The occurrence of cyclic AMP in archaebacteria

1986 • 18 citations

Bordetella pertussis adenylate cyclase: isolation and purification by calmodulin-sepharose 4B chromatography

1987 • 18 citations

Adenylate cyclase and cyclic AMP phosphodiesterase in Bradyrhizobium japonicum bacteroids

1989 • 18 citations

Evidence against direct involvement of cyclic GMP or cyclic AMP in bacterial chemotactic signaling

1986 • 17 citations

Role of 2-ketobutyrate as an alarmone in E. coli K12: Inhibition of adenylate cyclase activity mediated by the phosphoenolpyruvate: Glycose phosphotransferase transport system

1984 • 17 citations

Cyclic AMP interferes with pattern formation in the cyanobacteriumAnabaena variabilis

1981 • 17 citations

Escherichia coli K-12 mutation that inactivates biodegradative threonine dehydratase by transposon Tn5 insertion

1984 • 16 citations

Energy status, growth and nitrogenase activity in continuous cultures of Rhizobium sp. strain CB756 supplied with NH+4 and various rates of aeration

1981 • 16 citations

Relationships between the calmodulin-dependent adenylate cyclases produced by Bacillus anthracis and Bordetella pertussis

1988 • 16 citations

Independence of cyclic AMP and relA gene stimulation of glycogen synthesis in intact Escherichia coli cells

1985 • 15 citations

Glucose-mediated catabolite repression of the tricarboxylic acid cycle as an explanation for increased acetic acid production in suicidal Aeromonas strains

1990 • 15 citations

Acyadeletion mutant ofEscherichia colidevelops thermotolerance but does not exhibit a heat-shock response

1990 • 14 citations

The effect of cyclic AMP on anaerobic growth of Escherichia coli

1973 • 14 citations

Mutations that affect transcription and cyclic AMP-CRP regulation of the adenylate cyclase gene (cya) of Salmonella typhimurium.

1990 • 14 citations

Transcription of the speC (ornithine decarboxylase) gene of Escherichia coli is repressed by cyclic AMP and its receptor protein

1986 • 14 citations

Phasmid P4: manipulation of plasmid copy number and induction from the integrated state

1984 • 13 citations

Organization of the adenyl cyclase (cya) locus of Rhizobium meliloti

1986 • 13 citations

Control mechanism of the Escherichia coli K-12 cell cycle is triggered by the cyclic AMP-cyclic AMP receptor protein complex

1989 • 13 citations

Cyclic AMP and its receptor protein are required for expression of transfer genes of conjugative plasmid F in Escherichia coli

1983 • 13 citations

Characteristics of Cyclic AMP Transport by Marine Bacteria

1987 • 13 citations

Characterization of the binding of cAMP and cGMP to the CRP^*598 mutant of theE. colicAMP receptor protein

1990 • 13 citations

Effect of mutations in the cyclic AMP receptor protein-binding site on araBAD and araC expression

1989 • 12 citations

Activation of expression of the Escherichia coli cir gene by an iron-independent regulatory mechanism involving cyclic AMP-cyclic AMP receptor protein complex

1990 • 12 citations

Enzymatic synthesis of 3′:5′ cyclic AMP using Bordetella pertussis adenylate cyclase co-immobilized with calmodulin on agarose beads

1988 • 12 citations

A deficiency in cyclic AMP results in pH-sensitive growth of Escherichia coli K-12

1988 • 12 citations

E. colil-asparaginase II production in the presence and absence of catabolite activating protein

1983 • 11 citations

Expression of heat-labile enterotoxin genes is under cyclic AMP control inEscherichia coli

1990 • 11 citations

Physical identification of an internal promoter, ilvAp, in the distal portion of the ilvGMEDA operon

1989 • 11 citations

The effect of inorganic phosphate on cyclic adenosine 3′, 5′-monophosphate in streptomycin-producing cultures of Streptomyces griseus

1981 • 11 citations

Transcription of pfl is regulated by anaerobiosis, catabolite repression, pyruvate, and oxrA: pfl::Mu dA operon fusions of Salmonella typhimurium

1989 • 11 citations

Effects of aerobic and anaerobic shock on catabolite repression in cyclic AMP suppressor mutants of Escherichia coli

1983 • 11 citations

Adenylate Cyclase Activity During Phenotypic Variation of Bordetella pertussis

1985 • 11 citations

Control of minicell producing cell division by cAMP-receptor protein complex in Escherichia coli

1979 • 10 citations

Possible role of ATP and cyclic AMP in glass attachment ofMycoplasma pneumoniae

1981 • 10 citations

Bordetella pertussis adenylate cyclase inactivation by the host cell

1989 • 10 citations

Cyclic AMP phosphodiesterase in Thermomonospora curvata

1987 • 10 citations

Extracellular cAMP formation from host cell ATP by Bordetella pertussis adenylate cyclase

1988 • 10 citations

Isolation of a protein fraction from Bordetella pertussis that facilitates entry of the calmodulin-sensitive adenylate cyclase into animal cells

1989 • 10 citations

Expression of the adenylate cyclase gene during cell elongation in Escherichia coli K-12

1986 • 10 citations

Cyclic AMP and Cyclic GMP Control of Synthesis of Constitutive Enzymes in Escherichia coli

1982 • 9 citations

The dependence of Escherichia coli asparaginase II formation on cyclic AMP and cyclic AMP receptor protein

1978 • 9 citations

Analysis of sequence elements important for expression and regulation of the adenylate cyclase gene (cya) of Salmonella typhimurium.

1990 • 9 citations

Catabolite repression of thiosulfate reduction bySalmonella typhimurium

1987 • 9 citations

Cyclic AMP is not detectable in Clostridium perfringens

1983 • 9 citations

Relationships between growth, cyclic amp and tylosin production in two mutants of Streptomyces fradiae

1982 • 8 citations

Bacterial growth and the concentrations of cyclic nucleotides inLegionella pneumophila cultures

1985 • 8 citations

Possible role of cAMP in the synthesis of β-glucanases and β-xylanases ofBacillus circulansWL-12

1984 • 8 citations

Regulation ofEscherichia coli catalases by anaerobiosis and catabolite repression

1990 • 8 citations

Identification of cyclic AMP-CRP binding sites in the intercistronic regulatoryuxaCA-exuTregion ofEscherichia coli

1986 • 8 citations

Expression of the adenyl cyclase-encoding gene (cya) of Rhizobium meliloti F34: existence of two cya genes?

1989 • 8 citations

Possible mechanism of the allosteric activation of cAMP receptor protein

1985 • 7 citations

Purification and properties of 3?,5?-cyclic nucleotide phosphodiesterase from Rhizobium fredii MAR-1

1986 • 7 citations

Cyclic adenosine 3′:5′-Monophosphate receptor protein: Interaction with E. coli RNA polymerase

1980 • 7 citations

Reversal by Cyclic AMP of the Urea-induced Inhibition of Synthesis of a Catabolite-repressible Enzyme in Vibrio cholerae

1987 • 7 citations

Isolation of a cAMP-requiring mutant inEscherichia coliK-12: evidence of growth regulation viaN-acetylglucosamine metabolism controlled by cAMP

1988 • 7 citations

The intracellular concentration of cyclic adenosine 3′,5′-monophosphate is constant throughout the cell cycle ofEscherichia coli

1984 • 6 citations

Cyclic adenosine 3′,5′-monophosphate inRhodopseudomonas capsulata

1983 • 6 citations

Variations in levels of cAMP, DNA and RNA in Streptomyces alboniger under conditions of aerial mycelium formation and repression

1985 • 6 citations

Influence of cyclic AMP on the incorporation of [1-14C]acetate into lipids of whole cells and spheroplasts ofMycobacterium smegmatisATCC14468

1981 • 6 citations

Generation of deletions in the 3'-flanking sequences of the Escherichia coli crp gene that induce cyclic AMP suppressor functions

1987 • 6 citations

Cloning and molecular characterization of csm mutations allowing expression of catabolite-repressible operons in the absence of exogenous cyclic AMP

1986 • 6 citations

Cyclic GMP and Cyclic AMP Binding Proteins in Myxococcus xanthus

1984 • 6 citations

Effect of the carbon source and cyclic AMP on isocitrate dehydrogenase, succinate dehydrogenase, and malate dehydrogenase in Klebsiella pneumoniae C3

1982 • 5 citations

Physiological responses of Bacillus species to concanavalin A. 2. Effect on growth, oxygen uptake, enzyme activities and intracellular cyclic guanosine 3',5'-monophosphate level of B. cereus ATCC 14579.

1984 • 5 citations

Inhibition of growth of Rhizobium japonicum by cyclic GMP

1985 • 5 citations

Glucose repression of anaerobic genes ofEscherichia coliis independent of cyclic AMP

1988 • 5 citations

Intracellular adenosine triphosphate and cyclic adenosine 3′,5′-monophosphate concentrations during derepression of actinomycin biosynthesis

1982 • 4 citations

Regulation of envelope-growth in Escherichia coli: horizontal envelope-growth by a process under cyclic AMP control.

1981 • 4 citations

Regulation of acetohydroxy acid synthase activities in adenyl cyclase-deficient strains of Escherichia coli K-12

1983 • 4 citations

Influence of cyclic AMP on photosynthetic development in Rhodospirillum rubrum

1984 • 4 citations

Derepression of Sporulation and Synthesis of Mycobacillin and Dipicolinic Acid by Guanosine 3':5'-Cyclic Monophosphate under Conditions of Glucose Repression in Bacillus subtilis

1985 • 4 citations

The effect of gyrase inhibitors and cyclic AMP on induction and glucose repression of the 6-hydroxy-nicotine oxidases in Arthrobacter oxidans

1982 • 3 citations

Influence of cyclic AMP on the growth response and anaerobic metabolism of carbon monoxide in Rhodocyclus gelatinosus

1988 • 3 citations

Dependence of turimycin biosynthesis on different substrates and its relationship to cyclic AMP levels ofStreptomyces hygroscopicus

1982 • 3 citations

A new pleiotropic mutation causing defective carbohydrate uptake in Escherichia coli K-12: isolation, mapping, and preliminary characterization

1988 • 3 citations

Identification and characterization of a third form (D3) of cyclic 3'5'-nucleotide phosphodiesterase from rhizobwm fredii

1989 • 3 citations

Hyperproduction of extracellular protease 1 inVibrio parahaemolyticusmutants deficient in cyclic adenosine 3′,5′-monophosphate or its binding protein

1983 • 2 citations

Evidence that cyclic AMP stimulates bacterial glycogen synthesis by relieving AMP inhibition of and by increasing the cellular level of ADP-glucose synthetase

1984 • 2 citations

Comparison of extracellular & intracellular level of cyclic AMP between the toxinogenic & non-toxinogenic strains of Vibrio cholerae.

1981 • 1 citations

Measurement of cAMP in Thermomonospora curvata by anion exchange HPLC

1989 • 1 citations