Elicitation of specific cytotoxic T cells by immunization with malaria soluble synthetic polypeptides.

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

Isolation of cDNA clones encoding T cell-specific membrane-associated proteins

1984 • 1,239 citations

Introduction of soluble protein into the class I pathway of antigen processing and presentation

1988 • 1,105 citations

Solid Phase Synthesis

1986 • 986 citations

Protective Immunity produced by the Injection of X-irradiated Sporozoites of Plasmodium berghei

1967 • 928 citations

Structure of the Gene Encoding the Immunodominant Surface Antigen on the Sporozoite of the Human Malaria Parasite Plasmodium falciparum

1984 • 716 citations

Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria

1989 • 505 citations

CD8+ T cells (cytotoxic/suppressors) are required for protection in mice immunized with malaria sporozoites.

1988 • 477 citations

Peptide synthesis. Part 2. Procedures for solid-phase synthesis using N^α-fluorenylmethoxycarbonylamino-acids on polyamide supports. Synthesis of substance P and of acyl carrier protein 65–74 decapeptide

1981 • 396 citations

Immunization of Man against Falciparum and Vivax Malaria by Use of Attenuated Sporozoites *

1975 • 375 citations

Antigen Presentation Pathways to Class I and Class II MHC‐Restricted T Lymphocytes

1987 • 322 citations

Rationale for the Development of an Engineered Sporozoite Malaria Vaccine

1989 • 295 citations

Cytotoxic T cells recognize a peptide from the circumsporozoite protein on malaria-infected hepatocytes.

1990 • 210 citations

Circumsporozoite proteins of malaria parasites

1985 • 196 citations

Cytotoxic T cells specific for the circumsporozoite protein of Plasmodium falciparum

1988 • 180 citations

Sporozoite Vaccine Induces Genetically Restricted T Cell Elimination of Malaria from Hepatocytes

1989 • 177 citations

H-2Kd-restricted antigenic peptides share a simple binding motif.

1991 • 145 citations

Serum angiotensin-1 converting enzyme activity processes a human immunodeficiency virus 1 gp160 peptide for presentation by major histocompatibility complex class I molecules.

1992 • 110 citations

Immunity to sporozoite-induced malaria infeciton in mice. I. The effect of immunization of T and B cell-deficient mice.

1977 • 109 citations

Extracellular processing of peptide antigens that bind class I major histocompatibility molecules.

1992 • 107 citations

T helper epitopes enhance the cytotoxic response of mice immunized with MHC class I-restricted malaria peptides

1992 • 97 citations

Synthetic peptides as antigens and competitors in recognition by H-2-restricted cytolytic T cells specific for HLA.

1988 • 97 citations

Differential stability of antigenic MHC class I-restricted synthetic peptides.

1991 • 66 citations

Parasite polymorphism present within minimal T cell epitopes of Plasmodium falciparum circumsporozoite protein.

1988 • 48 citations

Two types of sequence polymorphism in the circumsporozoite gene of Plasmodium falciparum

1992 • 29 citations

Immunodominance of a recombinant T-cell epitope depends on its molecular environment

1993 • 22 citations

Carboxyl terminus structural requirements for glycosylphosphatidylinositol anchor addition to cell surface proteins

1993 • 10 citations