Stimulation of cell proliferation and estrogenic response by adrenal C19-delta 5-steroids in the ZR-75-1 human breast cancer cell line.

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1973 • 12,522 citations

Estrogen control of progesterone receptor in human breast cancer. Correlation with nuclear processing of estrogen receptor.

1978 • 797 citations

Endogenous concentration and subcellular distribution of androgens in normal and malignant human breast tissue.

1985 • 446 citations

Establishment and characterization of three new continuous cell lines derived from human breast carcinomas.

1978 • 373 citations

Steroid-hormone receptors in breast cancer

1984 • 327 citations

Effect of estradiol on human breast cancer cells in culture.

1983 • 272 citations

Effects of a new antiestrogen, keoxifene (LY156758), on growth of carcinogen-induced mammary tumors and on LH and prolactin levels

1983 • 177 citations

Estrogenic effects of physiological concentrations of 5-androstene-3 beta, 17 beta-diol and its metabolism in MCF7 human breast cancer cells.

1981 • 124 citations

The conversion of androstenedione to estrone, estradiol, and testosterone in breast tissue

1980 • 123 citations

The estrogenic and antiestrogenic activities of androgens in female target tissues

1983 • 105 citations

Metabolism of dehydroepiandrosterone by hormone dependent and hormone independent human breast carcinoma

1975 • 95 citations

Effects of estradiol and tamoxifen on human breast cancer cells in serum-free culture.

1984 • 91 citations

Evidence and Characterization of the Binding of Two₃H-Labeled Androgens to the Estrogen Receptor*

1979 • 83 citations

A simple method to determine whole cell uptake of radiolabelled oestrogen and progesterone and their subcellular localization in breast cancer cell lines in monolayer culture

1984 • 80 citations

PARAENDOCRINE BEHAVIOUR OF HUMAN BREAST CARCINOMA: IN VITRO TRANSFORMATION OF STEROIDS TO PHYSIOLOGICALLY ACTIVE HORMONES

1968 • 79 citations

A radioimmunoassay for the estimation of serum dehydroepiandrosterone sulphate in normal and pathological sera

1975 • 73 citations

Estrogenic Effects of 5-Androstene-3β,17β-Diol at Physiological Concentrations and Its Possible Implication in the Etiology of Breast Cancer*

1983 • 69 citations

Steroid Hormone Receptors in Human Breast Cancer

1983 • 66 citations

Androgen interaction with the oestrogen receptor in human tissues

1979 • 59 citations

Dehydroepiandrosterone: Kinetics of Metabolism in Normal Men and Women*

1978 • 54 citations

Androstenediol Levels in Human Peripheral Plasma¹²

1972 • 44 citations

The effects of 17β estradiol and tamoxifen on the ZR-75-1 human breast cancer cell line in defined medium

1980 • 36 citations

Dehydroepiandrosterone and androst-5-ene-3 beta,17 beta-diol in human mammary cancer cytosolic and nuclear compartments and their relationship to estrogen receptor.

1980 • 35 citations

Δ⁵-Androstenediol: Kinetics of Metabolism and Binding to Plasma Proteins in Normal Men and Women1

1976 • 35 citations

Adrenal androgen concentrations in breast tumours and in normal breast tissue. The relationship to oestradiol metabolism

1984 • 34 citations

Keoxifene shows pure antiestrogenic activity in pituitary gonadotrophs

1985 • 33 citations

Products of dehydroepiandrosterone metabolism by human mammary tumors and their influence on estradiol receptor binding

1978 • 33 citations

Continuous culture and soft agarose cloning of multiple human breast carcinoma cell lines in serum-free medium.

1984 • 31 citations

Growth regulation of human breast cancer.

1985 • 25 citations

Antiestrogen therapy of breast cancer.

1983 • 18 citations

Rational approaches to the hormonal treatment of breast cancer.

1983 • 17 citations

Influence of Intratumoral Estradiol Biosynthesis on Estrogen Receptors

1984 • 16 citations