Autoantibodies in rheumatoid arthritis and their clinical significance.

Textbook of Rheumatology

1985 • 1,671 citations

The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide

2000 • 1,444 citations

Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies.

1998 • 1,402 citations

From Systemic T Cell Self-Reactivity to Organ-Specific Autoimmune Disease via Immunoglobulins

1999 • 689 citations

The Major Synovial Targets of the Rheumatoid Arthritis-Specific Antifilaggrin Autoantibodies Are Deiminated Forms of the α- and β-Chains of Fibrin

2001 • 629 citations

Arthritis Provoked by Linked T and B Cell Recognition of a Glycolytic Enzyme

1999 • 620 citations

Autoantibodies in the diagnosis of systemicrheumatic diseases

1995 • 564 citations

Assessment of antibodies to double-stranded DNA induced in rheumatoid arthritis patients following treatment with infliximab, a monoclonal antibody to tumor necrosis factor α: Findings in open-label and randomized placebo-controlled trials

2000 • 535 citations

The Epitopes Targeted by the Rheumatoid Arthritis-Associated Antifilaggrin Autoantibodies are Posttranslationally Generated on Various Sites of (Pro)Filaggrin by Deimination of Arginine Residues

1999 • 481 citations

Rheumatoid arthritis associated autoantibodies in patients with synovitis of recent onset

2000 • 360 citations

Anti-keratin antibodies in rheumatoid arthritis.

1979 • 333 citations

The cytokeratin filament-aggregating protein filaggrin is the target of the so-called "antikeratin antibodies," autoantibodies specific for rheumatoid arthritis.

1993 • 259 citations

In the rheumatoid pannus, anti-filaggrin autoantibodies are produced by local plasma cells and constitute a higher proportion of IgG than in synovial fluid and serum

2000 • 226 citations

Autoantibodies to GPI in rheumatoid arthritis: linkage between an animal model and human disease

2001 • 212 citations

The Sa system: a novel antigen-antibody system specific for rheumatoid arthritis.

1994 • 185 citations

The stress protein BiP is overexpressed and is a major B and T cell target in rheumatoid arthritis

2001 • 178 citations

Manual of Biological Markers of Disease

1996 • 166 citations

In Vivo Neutralization of TNF-α Promotes Humoral Autoimmunity by Preventing the Induction of CTL

2001 • 152 citations

Anti-Sa antibody is an accurate diagnostic and prognostic marker in adult rheumatoid arthritis.

1999 • 129 citations

PATHOGENESIS OF RHEUMATOID ARTHRITIS

1997 • 128 citations

Development of Anti‐dsDNA Autoantibodies Prior to Clinical Diagnosis of Systemic Lupus Erythematosus

2001 • 128 citations

Autoimmune response to the spliceosome

1995 • 126 citations

Demonstration of a new antinuclear antibody (ANTI‐RA33) that is highly specific for rheumatoid arthritis

1989 • 111 citations

Proteinase 3, Wegener's autoantigen: from gene to antigen

2001 • 106 citations

Purification and partial sequencing of the nuclear autoantigen RA33 shows that it is indistinguishable from the A2 protein of the heterogeneous nuclear ribonucleoprotein complex.

1992 • 103 citations

[Antikeratin antibodies in rheumatoid arthritis].

1991 • 85 citations

AUTOANTIBODY TO THE NUCLEAR ANTIGEN RA33: A MARKER FOR EARLY RHEUMATOID ARTHRITIS

1993 • 85 citations

DIAGNOSTIC VALUE OF ANTI-RA33 ANTIBODY, ANTIKERATIN ANTIBODY, ANTIPERINUCLEAR FACTOR AND ANTINUCLEAR ANTIBODY IN EARLY RHEUMATOID ARTHRITIS: COMPARISON WITH RHEUMATOID FACTOR

1996 • 80 citations

Anti-topoisomerase I (Anti-Scl-70) antibodies in patients with systemic lupus erythematosus

2001 • 76 citations

Sensitivity and specificity of anti-Sa autoantibodies for rheumatoid arthritis

1999 • 61 citations

B and T Cell Responses to the Spliceosomal Heterogeneous Nuclear Ribonucleoproteins A2 and B1 in Normal and Lupus Mice

2000 • 48 citations

The MRL-Ipr/Ipr Mouse. A Model for the Study of Rheumatoid Arthritis

1988 • 46 citations

Are autoantibodies active players or epiphenomena?

1998 • 44 citations

Adenovirus-based overexpression of tissue inhibitor of metalloproteinases 1 reduces tissue damage in the joints of tumor necrosis factor ? transgenic mice

2001 • 42 citations

Serum‐serum interactions in autoimmune mice

1979 • 38 citations

Novel 68 kDa autoantigen detected by rheumatoid arthritis specific antibodies.

1995 • 36 citations

Anti-RA 33 antinuclear autoantibody in rheumatoid arthritis and mixed connective tissue disease: comparison with antikeratin and antiperinuclear antibodies.

1993 • 35 citations

The Antiperinuclear Factor and Antikeratin Antibody Systems

1995 • 28 citations

Anti-Jo-1 antibodies in polymyositis or dermatomyositis: evaluation by ELISA using recombinant fusion protein Jo-1 as antigen

1998 • 26 citations

Anti–topoisomerase I (Anti–Scl‐70) antibodies in patients with systemic lupus erythematosus

2001 • 5 citations

Sensitivity and specificity of anti-Sa autoantibodies for rheumatoid arthritis

1997 • 4 citations