Puffs and PCR: the in vivo dynamics of early gene expression during ecdysone responses in Drosophila

The Genetics and Biology of Drosophila

1978 • 3,910 citations

Quantitation of mRNA by the polymerase chain reaction.

1989 • 1,648 citations

The drosophila EcR gene encodes an ecdysone receptor, a new member of the steroid receptor superfamily

1991 • 958 citations

Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation

1992 • 719 citations

Illegitimate transcription: transcription of any gene in any cell type.

1989 • 647 citations

Temporal Control of Puffing Activity in Polytene Chromosomes

1974 • 632 citations

Sequence, structure, and codon preference of theDrosophilaribosomal protein 49 gene

1984 • 523 citations

Heterodimerization of the Drosophila ecdysone receptor with retinoid X receptor and ultraspiracle

1993 • 519 citations

Ecdysone : from chemistry to mode of action

1989 • 494 citations

The E75 ecdysone-inducible gene responsible for the 75B early puff in Drosophila encodes two new members of the steroid receptor superfamily.

1990 • 483 citations

The Drosophila Broad-Complex encodes a family of related proteins containing zinc fingers.

1991 • 440 citations

The Drosophila 74EF early puff contains E74, a complex ecdysone-inducible gene that encodes two ets-related proteins

1990 • 417 citations

Determinants of heat shock-induced chromosome puffing

1985 • 281 citations

Sequential gene activation by ecdysone in polytene chromosomes of Drosophila melanogaster

1974 • 271 citations

Die Puffs der Speicheldr�senchromosomen von Drosophila melanogaster

1962 • 265 citations

Temporal coordination of regulatory gene expression by the steroid hormone ecdysone.

1992 • 256 citations

Spatial and temporal patterns of E74 transcription during Drosophila development

1990 • 254 citations

Patterns of puffing activity in the salivary gland chromosomes of Drosophila

1967 • 225 citations

The Genetics and Biology of Drosophila, Vol. 1B

1976 • 200 citations

Quantitative estimation of minor mRNAs by cDNA‐polymerase chain reaction

1990 • 196 citations

Molecular interactions within the ecdysone regulatory hierarchy: DNA binding properties of the Drosophila ecdysone-inducible E74A protein

1990 • 195 citations

The radioimmune assay of ecdysteroid titres in drosophila melanogaster

1981 • 186 citations

Molecular organization of a Drosophila puff site that responds to ecdysone

1982 • 166 citations

Sequential gene activation by ecdysone in polytene chromosomes of Drosophila melanogaster

1973 • 163 citations

Ecdysone coordinates the timing and amounts of E74A and E74B transcription in Drosophila.

1991 • 147 citations

Sequential gene activation by ecdysone in polytene chromosomes of Drosophila melanogaster,

1976 • 128 citations

Hormones, puffs and flies: the molecular control of metamorphosis by ecdysone

1992 • 126 citations

The ecdysone-induced puffing cascade in Drosophila salivary glands: a Broad-Complex early gene regulates intermolt and late gene transcription.

1991 • 114 citations

Splicing Precedes Polyadenylation during Drosophila E74A Transcription

1990 • 100 citations

Induction of Puffs in Polytene Chromosomes of in vitro Cultured Salivary Glands of Drosophila melanogaster by Ecdysone and Ecdysone Analogues

1971 • 100 citations

Sequential gene activation by ecdysone in polytene chromosomes of Drosophila melanogaster,

1976 • 95 citations

Something old, some things new: The steroid receptor superfamily in drosophila

1991 • 80 citations

A member of the steroid hormone receptor gene family is expressed in the 20-OH-ecdysone inducible puff 75B inDrosophila melanogaster

1989 • 73 citations

Tissue-specific ecdysone responses: regulation of the Drosophila genes Eip28/29 and Eip40 during larval development

1992 • 71 citations

The normal developmental regulation of a cloned sgs3 ‘glue’ gene chromosomally integrated in Drosophila melanogaster by P element transformation.

1983 • 70 citations

Splicing precedes polyadenylation during Drosophila E74A transcription.

1990 • 63 citations

Sequential gene activation by ecdysone in polytene chromosomes of Drosophila melanogaster,

1976 • 61 citations

Steroid regulation of RNAs transcribed from the Drosophila 68C polytene chromosome puff

1984 • 59 citations

Patterns of E74A RNA and protein expression at the onset of metamorphosis in Drosophila

1991 • 59 citations

Comparative study of the function of polytene chromosomes in laboratory stocks of Drosophila melanogaster and the l(3)tl mutant (lethal tumorous larvae)

1974 • 45 citations

Hormones, puffs and flies: the molecular control of metamorphosis by ecdysone

1992 • 38 citations

Sequential gene activation by ecdysteroids in polytene chromosomes ofDrosophila melanogaster

1982 • 34 citations

Sgs-3 chromatin structure and trans-activators: developmental and ecdysone induction of a glue enhancer-binding factor, GEBF-I, in Drosophila larvae.

1991 • 31 citations

Switching partners?

1992 • 13 citations