The Structure and Function of Chromatin

Genetic regulatory mechanisms in the synthesis of proteins

1961 • 6,378 citations

Evolution by gene duplication

1970 • 5,849 citations

A RAPID BANDING TECHNIQUE FOR HUMAN CHROMOSOMES

1971 • 5,049 citations

Gene Action in the X-chromosome of the Mouse (Mus musculus L.)

1961 • 3,881 citations

Repeated Sequences in DNA

1968 • 2,836 citations

ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS

1964 • 2,410 citations

Animal cytology and evolution

1980 • 2,302 citations

Gene Regulation for Higher Cells: A Theory

1969 • 2,022 citations

Non-Darwinian Evolution

1969 • 1,731 citations

TECHNIQUES FOR THE PRESERVAATION OF THREE‐DIMENSIONAL STRUCTURE IN PREPARING SPECIMENS FOR THE ELECTRON MICROSCOPE*

1951 • 1,477 citations

On the Regulation of DNA Replication in Bacteria

1963 • 1,441 citations

FORMATION AND DETECTION OF RNA-DNA HYBRID MOLECULES IN CYTOLOGICAL PREPARATIONS

1969 • 1,214 citations

The replication of DNA in Escherichia coli

1958 • 1,202 citations

New Technique for Distinguishing between Human Chromosomes

1971 • 1,168 citations

Chromosomal Localization of Mouse Satellite DNA

1970 • 1,119 citations

A two-step mechanism for the interaction of estradiol with rat uterus.

1968 • 1,013 citations

A Morphological Distinction between Neurones of the Male and Female, and the Behaviour of the Nucleolar Satellite during Accelerated Nucleoprotein Synthesis

1949 • 1,000 citations

Factor Stimulating Transcription by RNA Polymerase

1969 • 983 citations

Localization of heterochromatin in human chromosomes

1971 • 965 citations

On the mechanism of DNA replication in mammalian chromosomes

1968 • 950 citations

Multiple Forms of DNA-dependent RNA Polymerase in Eukaryotic Organisms

1969 • 945 citations

Specific Inhibition of Nuclear RNA Polymerase II by α-Amanitin

1970 • 856 citations

Controlling Elements and the Gene

1956 • 837 citations

THE ORGANIZATION AND DUPLICATION OF CHROMOSOMES AS REVEALED BY AUTORADIOGRAPHIC STUDIES USING TRITIUM-LABELED THYMIDINEE

1957 • 824 citations

Specific Gene Amplification in Oocytes

1968 • 811 citations

Termination Factor for RNA Synthesis

1969 • 801 citations

T4 Bacteriophage Gene 32: A Structural Protein in the Replication and Recombination of DNA

1970 • 793 citations

lac repressor-operator interaction

1970 • 791 citations

Interaction between DNA and an Escherichia coli protein ω

1971 • 749 citations

Isolation of an E. coli Strain with a Mutation affecting DNA Polymerase

1969 • 749 citations

Lac represser-operator interaction

1973 • 699 citations

SALIVARY CHROMOSOME MAPS

1935 • 682 citations

A receptor molecule for estrogens: isolation from the rat uterus and preliminary characterization.

1966 • 680 citations

The 24 fluorescence patterns of the human metaphase chromosomes - distinguishing characters and variability

2009 • 665 citations

ISOLATION OF THE LAC REPRESSOR

1966 • 657 citations

HISTONE, A SUPPRESSOR OF CHROMOSOMAL RNA SYNTHESIS

1962 • 590 citations

Localization and kinetics of formation of nuclear heterodisperse RNA, cytoplasmic heterodisperse RNA and polyribosome-associated messenger RNA in HeLa cells

1968 • 572 citations

THE EFFECT OF COLCHICINE ON ROOT MITOSES IN ALLIUM

2010 • 564 citations

Organ-specific restriction of transcription in mammalian chromatin

1968 • 556 citations

Chemical differentiation along metaphase chromosomes

1968 • 552 citations

NON-DISJUNCTION AS PROOF OF THE CHROMOSOME THEORY OF HEREDITY

1916 • 542 citations

New RNA Polymerase from Escherichia coli infected with Bacteriophage T7

1970 • 534 citations

MOLECULAR HYBRIDIZATION OF RADIOACTIVE DNA TO THE DNA OF CYTOLOGICAL PREPARATIONS

1969 • 532 citations

Template properties of liver chromatin

1966 • 530 citations

A Polynucleotide Segment Rich in Adenylic Acid in the Rapidly-Labeled Polyribosomal RNA Component of Mouse Sarcoma 180 Ascites Cells

1971 • 521 citations

Separation and Characterization of the Subunits of Ribonucleic Acid Polymerase

1969 • 520 citations

The specific inhibition of the DNA-directed RNA synthesis by rifamycin

1967 • 503 citations

Polyadenylic Acid Sequences in the Heterogeneous Nuclear RNA and Rapidly-Labeled Polyribosomal RNA of HeLa Cells: Possible Evidence for a Precursor Relationship

1971 • 503 citations

So much "junk" DNA in our genome.

1972 • 501 citations

Studies of Nuclear Acidic Proteins

1971 • 497 citations

THE DESOXYRIBONUCLEIC ACID CONTENT OF ANIMAL CELLS AND ITS EVOLUTIONARY SIGNIFICANCE

1951 • 493 citations

α-Amanitin: A specific inhibitor of one of two DNA-dependent RNA polymerase activities from calf thymus

1970 • 488 citations

The isolation and properties of deoxyribonucleoprotein particles containing single nucleic acid molecules

1959 • 484 citations

Chromosomal and Nuclear Location of Mouse Satellite DNA in Individual Cells

1970 • 470 citations

Adenosine 3‘,5‘-Phosphate in Escherichia coli

1965 • 469 citations

Rapidly labeled HeLa cell nuclear RNA. I. Identification by zone sedimentation of a heterogeneous fraction separate from ribosomal precursor RNA.

1966 • 465 citations

Heterochromatin

1966 • 462 citations

Structure of Chromatin

1971 • 462 citations

Repetitive DNA sequences in Drosophila

1971 • 458 citations

Specific Nucleolar and Nucleoplasmic RNA Polymerases

1970 • 454 citations

Studies on the Endoplasmic Reticulum

1960 • 452 citations

The Biology of Isolated Chromatin

1968 • 450 citations

The Phenomenon of Position Effect

1950 • 436 citations

CHROMOSIN, A DESOXYRIBOSE NUCLEOPROTEIN COMPLEX OF THE CELL NUCLEUS

1946 • 433 citations

THE EFFECTS OF UNEQUAL CROSSING OVER AT THE BAR LOCUS IN DROSOPHILA

1925 • 432 citations

Mechanism of Activation of Catabolite-Sensitive Genes: A Positive Control System

1970 • 430 citations

THE CYTOPLASMIC SYNTHESIS OF HISTONES IN HELA CELLS AND ITS TEMPORAL RELATIONSHIP TO DNA REPLICATION

1967 • 421 citations

ON THE ROLE OF HISTONES IN REGULATING RIBONUCLEIC ACID SYNTHESIS IN THE CELL NUCLEUS

1963 • 410 citations

Calf and Pea Histone IV

1969 • 393 citations

Heterogeneity of histones. I. A quantitative analysis of calf histones in very long polyacrylamide gels

1969 • 393 citations

Cyclic Re-use of the RNA Polymerase Sigma Factor

1969 • 392 citations

An Adenylic Acid-Rich Sequence in Messenger RNA of HeLa Cells and Its Possible Relationship to Reiterated Sites in DNA

1971 • 389 citations

Differential synthesis of the genes for ribosomal RNA during amphibian oögenesis.

1968 • 386 citations

Visualization of Bacterial Genes in Action

1970 • 385 citations

Sur une nouvelle technique d'analyse du caryotype humain.

1971 • 382 citations

Ribonucleic acids from animal cells

1968 • 379 citations

The Control of Ribonucleic Acid Synthesis in Escherichia coli

1970 • 366 citations

SISTER CHROMATID EXCHANGES IN TRITIUM-LABELED CHROMOSOMES

1958 • 364 citations

Cell Specificity of Histones

1950 • 363 citations

DNA Replication Patterns of Human Chromosomes

1963 • 362 citations

The rationale for an ordered arrangement of chromatin in the interphase nucleus.

1968 • 358 citations

Base Sequence and Evolution of Guinea-pig α-Satellite DNA

1970 • 357 citations

Adenine-rich Polymer associated with Rabbit Reticulocyte Messenger RNA

1970 • 355 citations

Mutants that make more lac repressor.

1968 • 354 citations

Deoxyribonucleic acid replication in meiosis of Chlamydomonas reinhardi

1967 • 352 citations

Lampbrush chromosomes of crested newtsTriturus cristatus(Laurenti)

1960 • 343 citations

Formation of the sex chromatin by a single X-chromosome in liver cells of Rattus norvegicus

1959 • 340 citations

Sequence-specific interaction of DNA and chromosomal protein

1969 • 337 citations

Giant-size rapidly labeled nuclear ribonucleic acid and cytoplasmic messenger ribonucleic acid in immature duck erythrocytes

1966 • 331 citations

DNA Polymerase II

1970 • 330 citations

SYNAPTINEMAL COMPLEX

1968 • 323 citations

Studies with DNA-cellulose Chromatography. I. DNA-binding Proteins from Escherichia coli

1968 • 320 citations

Chemical differentiation with fluorescent alkylating agents in Vicia faba metaphase chromosomes

1969 • 319 citations

Histones: Structure and Function

1971 • 313 citations

A new histone found only in mammalian tissues with little cell division

1969 • 302 citations

Nuclear Polyanions as De-Repressors of Synthesis of Ribonucleic Acid

1965 • 300 citations

[Specific gene amplification in oocytes].

1969 • 300 citations

The organization of genetic units in chromosomes

1967 • 299 citations

Behavior of polytene chromosomes of rhynchosciara angelae at different stages of larval development

1955 • 297 citations

The Bar "Gene" a Duplication

1936 • 296 citations

Deoxyribonucleic acid in amphibian eggs

1965 • 291 citations

Nucleotide Sequence Repetition: A Rapidly Reassociating Fraction of Mouse DNA

1966 • 288 citations

Specific Banding Patterns of Human Chromosomes

1971 • 288 citations

Chemical Studies of Histone Acetylation

1968 • 286 citations

ISOLATION OF THE λ PHAGE REPRESSOR

1967 • 285 citations

A cell-membrane bound fraction of bacterial DNA

1965 • 280 citations

ENZYMATIC INCORPORATION OF RIBONUCLEOSIDE TRIPHOSPHATES INTO THE INTERPOLYNUCLEOTIDE LINKAGES OF RIBONUCLEIC ACID

1960 • 279 citations

DNA binding of the lac repressor

1968 • 279 citations

lac repressor—Operator interaction

1970 • 279 citations

Die Ursache der gesetzmässigen Zahl, Lage, Form und Grösse pflanzlicher Nukleolen

1931 • 278 citations

Differential Uptake of Tritiated Thymidine into Hetero- and Euchromatin in Melanoplus and Secale

1959 • 274 citations

Cytological localization of DNA complementary to ribosomal RNA in polytene chromosomes of Diptera

1970 • 272 citations

Chromosomal Variation and Evolution

1966 • 271 citations

Limited heterogeneity of the major nonhistone chromosomal proteins

1970 • 271 citations

Properties and Composition of the Isolated Ribosomal DNA Satellite of Xenopus laevis

1968 • 269 citations

Effect of protein-bound RNA associated with chick embryo chromatin on template specificity of the chromatin

1969 • 267 citations

Phosphorylation of Nuclear Protein Early in the Course of Gene Activation in Lymphocytes

1966 • 266 citations

Induction of Zona Reaction in Golden Hamster Eggs by Cortical Granule Material

1971 • 266 citations

Late DNA Synthesis in Heterochromatin

1968 • 263 citations

Molecular Structure of Deoxyribose Nucleic Acid and Nucleoprotein

1955 • 261 citations

Reiteration and Clustering of DNA Sequences Complementary to Histone Messenger RNA

1971 • 259 citations

Isolation of a cell membrane-DNA-nascent RNA complex from bacteria

1969 • 258 citations

The properties of repressor and the kinetics of its action

1965 • 257 citations

Specific Binding of the λ Phage Repressor to λ DNA

1967 • 254 citations

Messenger and Heterogeneous Nuclear RNA in HeLa Cells: Differential Inhibition by Cordycepin

1970 • 253 citations

The Isolation and Characterization of Adenosine Monophosphate-rich Polynucleotides Synthesized by Ehrlich Ascites Cells

1969 • 248 citations

Mammalian X-Chromosome Action: Inactivation Limited in Spread and in Region of Origin

1963 • 247 citations

Physical and biological properties of soluble nucleohistones

1964 • 244 citations

Chromatid structure: relationship between DNA content and nucleotide sequence diversity

1971 • 241 citations

Lac DNA, RNA Polymerase and Cyclic AMP Receptor Protein, Cyclic AMP, Lac Repressor and Inducer are the Essential Elements for Controlled Lac Transcription

1971 • 238 citations

A new method for the rapid isolation of chromosomes, mitotic apparatus, or nuclei from mammalian fibroblasts at near neutral pH

1970 • 237 citations

Proteins of chromatin in template restriction

1971 • 237 citations

Rifampicin Sensitivity of the Components of DNA-dependent RNA Polymerase

1969 • 235 citations

Nucleic acid starvation of chromosomes inTrillium

1940 • 234 citations

Isolation and characterization of mouse and guinea pig satellite deoxyribonucleic acids

1968 • 234 citations

Initiation of DNA‐Dependent RNA Synthesis and the Effect of Heparin on RNA Polymerase

1967 • 233 citations

RNA transcribed from reconstituted nucleoprotein is similar to natural RNA

1969 • 232 citations

The Resolution of Four Lysine-rich Histones Derived from Calf Thymus

1966 • 232 citations

Evidence for Ribonucleic Acid Molecules Restricted to the Cell Nucleus^*

1967 • 229 citations

Proteins of chromatin in template restriction

1971 • 228 citations

Species and Organ Specificity in Very Lysine-rich Histones

1968 • 227 citations

Chapter 1 On “Masked” Forms of Messenger Rna in Early Embryogenesis and in Other Differentiating Systems

1966 • 221 citations

Autoradiography of HeLa cell DNA

1966 • 221 citations

THE TURNOVER OF NUCLEAR DNA-LIKE RNA IN HELA CELLS

1968 • 219 citations

On the structural organization of operon and the regulation of RNA synthesis in animal cells

1969 • 216 citations

Regulation of chromosome replication and segregation in bacteria

1966 • 215 citations

THE COMPOSITION AND STRUCTURE OF ISOLATED CHROMOSOMES

1951 • 214 citations

Some properties of the single strands isolated from the DNA of the nuclear satellite of the mouse (Mus musculus)

1969 • 213 citations

THE ANNUAL INVITATION LECTURE ULTRASTRUCTURE AND MOLECULAR ORGANIZATION OF GENETIC SYSTEMS

1961 • 212 citations

On the Rule of Different Subunits of DNA-Dependent RNA Polymerase from E. coli in the Transcription Process

1970 • 212 citations

Evolution of Cellular DNA Content in Teleost Fishes

1968 • 211 citations

Phosphoprotein metabolism in isolated lymphocyte nuclei.

1966 • 208 citations

PHOSPHORYLATION OF LIVER HISTONE FOLLOWING THE ADMINISTRATION OF GLUCAGON AND INSULIN

1969 • 208 citations

Location of Satellite and Homogeneous DNA Sequences on Human Chromosomes

1971 • 208 citations

The ultrastructure and spatial organization of the metaphase kinetochore in mitotic rat cells

1967 • 207 citations

Localization of 5 S RNA Genes on Drosophila Chromosomes by RNA-DNA Hybridization

1970 • 206 citations

Distribution of constitutive heterochromatin in mammalian chromosomes

1971 • 206 citations

Histones and Other Nuclear Proteins

1965 • 205 citations

Macromolecular Organization of Nuclei and Chromosomes: A Folded Fibre Model Based on Whole-Mount Electron Microscopy

1965 • 205 citations

Action of Adenosine 3',5'-Monophosphate-dependent Histone Kinase in Vivo

1969 • 203 citations

Non-Disjunction as Proof of the Chromosome Theory of Heredity (Concluded)

1916 • 201 citations

Heterochromatic Chromosomes in the Coccids

1964 • 200 citations

Structure of chromosomes

1968 • 198 citations

Purification and DNA Synthesis in Cell-Free Extracts: Properties of DNA Polymerase II

1971 • 198 citations

Further fractionations of histones from calf thymus

1962 • 197 citations

Essential Chemical Requirements for Induction of Allergic Encephalomyelitis

1971 • 195 citations

Handbuch der Blütenbiologie

1904 • 192 citations

Initiation of deoxyribonucleic acid replication at the nuclear membrane in human cells

1968 • 192 citations

Chromosomal Proteins

1969 • 192 citations

Super-helical Model for Nucleohistone

1967 • 189 citations

Die somatische Heteropyknose bei Drosophila melanogaster und ihre genetische Bedeutung

1933 • 188 citations

Selective Synthesis of a Nuclear Acidic Protein in Liver Cells stimulated by Cortisol

1970 • 187 citations

Change in the Template Specificity of RNA Polymerase during Sporulation of Bacillus subtilis

1969 • 184 citations

CHROMOSOME STRUCTURE

1970 • 183 citations

Identification of Each Human Chromosome with a Modified Giemsa Stain

1971 • 183 citations

Chemical Studies of Histone Acetylation

1968 • 182 citations

Role of non‐histone components in determining organ specificity of rabbit chromatins

1970 • 181 citations

Conformational changes associated with f-1 histone-deoxyribonucleic acid complexes. Circular dichroism studies

1970 • 181 citations

Non-inducible mutants of the regulator gene in the “lactose” system of Escherichia coli

1964 • 181 citations

Repeated sequences in human DNA

1970 • 180 citations

Description of two procedures which avoid the use of extreme pH conditions for the resolution of components isolated from chromatins prepared from pig cerebellar and pituitary nuclei

1970 • 179 citations

Properties of the growing point region in the bacterial chromosome

1967 • 179 citations

Localization and Function of Heterochromatin in Drosophila Melanogaster

1951 • 178 citations

Localization of mouse satellite DNA in constitutive heterochromatin

1970 • 177 citations

Amino-acid Sequence of Slightly Lysine-rich Histone

1970 • 170 citations

RNA and protein metabolism in the maturation of the nucleated chicken erythrocyte

1963 • 168 citations

On the Similarity of Plant and Animal Histones^*

1966 • 167 citations

HUMAN SEX CHROMOSOME ABNORMALITIES IN RELATION TO DNA REPLICATION AND HETEROCHROMATINIZATION

1963 • 167 citations

The Relationship between Glucocorticoid Binding and Tyrosine Aminotransferase Induction in Hepatoma Tissue Culture Cells

1970 • 166 citations

Autoradiographic Detection of Molecular Hybrids between rRNA and DNA in Tissue Sections

1970 • 165 citations

Specific Binding of Rat Liver Nuclear Proteins to DNA

1970 • 165 citations

Comparative DNA values and chromosome complements of eight species of fishes

1966 • 164 citations

Variegation in Drosophila and the Inert Chromosome Regions

1936 • 164 citations

DNA strand reassociation and polyribonucleotide binding in the African green monkey, Cercopithecus aethiops

1971 • 161 citations

CHROMOSOMAL AND SUBCHROMOSOMAL INACTIVATION

1968 • 160 citations

Structural Alteration of RNA Polymerase during Sporulation

1970 • 159 citations

Staining of Satellite DNA in Metaphase Chromosomes

1971 • 159 citations

End-to-end chromosome attachments in mitotic interphase and their possible significance to meiotic chromosome pairing

1969 • 159 citations

Localization of repetitive DNA in the chromosomes of Microtus agrestis by means of in situ hybridization

1971 • 158 citations

The Isolation, Properties, and Possible Functions of Chromatin Acidic Proteins

1967 • 157 citations

Structural Analysis of the Glycine-rich, Arginine-rich Histone

1969 • 157 citations

THE FINE STRUCTURE OF MITOSIS IN RAT THYMIC LYMPHOCYTES

1965 • 157 citations

Histone-bound RNA, a component of native nucleohistone.

1965 • 156 citations

Functional Organization of Genetic Material as a Product of Molecular Evolution

1971 • 155 citations

Messenger RNA in avian erythroblasts at the transcriptional and translational levels and the problem of regulation in animal cells

1968 • 155 citations

THE ORGANIZATION OF NUCLEI AND CHROMOSOMES IN HONEYBEE EMBRYONIC CELLS

1965 • 154 citations

The genes for ribosomal RNA during oögenesis.

1969 • 154 citations

Effect of the Androgen-insensitivity Mutation on a Cytoplasmic Receptor for Dihydrotestosterone

1971 • 153 citations

Restoration of operon activity by suppressors

1963 • 152 citations

Factor Necessary for Ribosomal RNA Synthesis

1970 • 152 citations

Mammalian Oocytes: X Chromosome Activity

1969 • 151 citations

STUDIES ON ACIDIC NUCLEAR PROTEINS OF THE WALKER TUMOR AND LIVER.

1963 • 151 citations

Evidence for a ‘Folded-Fibre’ Organization in Human Chromosomes

1966 • 151 citations

Role of the Receptor in the Mechanism of Action of Adenosine 3′:5′-Cyclic Monophosphate

1971 • 149 citations

Towards an understanding of the mechanism of heredity

1969 • 147 citations

X-ray diffraction studies of the molecular structure of nucleohistone and chromosomes

1959 • 147 citations

Changing patterns of histone acetylation and RNA synthesis in regeneration of the liver.

1968 • 147 citations

On the Complexity of Calf Thymus Histone^*

1962 • 147 citations

THE RELATIONSHIP BETWEEN RNA SYNTHESIS AND LOOP STRUCTURE IN LAMPBRUSH CHROMOSOMES

1963 • 145 citations

Some properties of a nuclear binding site of estradiol

1967 • 145 citations

The syndrome of congenital telangiectaticerythema and stunted growth

1966 • 144 citations

Repeated sequences in the DNA of Drosophila and their localization in giant chromosomes

1970 • 144 citations

Histones and Gene Function

1963 • 143 citations

Genetic information in oocyte RNA

1971 • 143 citations

Molecular Mechanisms of Chromosome Pairing, Folding and Function

1971 • 142 citations

The molecular structure of nucleohistone (DNH)

1970 • 142 citations

CONTROLLING ELEMENTS IN THE MOUSE X CHROMOSOME

1967 • 141 citations

HÆMOGLOBIN-H DISEASE DUE TO A UNIQUE HÆMOGLOBIN VARIANT WITH AN ELONGATED α-CHAIN

1971 • 141 citations

Association of chromatin fibers with the annuli of the nuclear membrane

1970 • 141 citations

The relationship between patterns of DNA replication and of Quinacrine fluorescence in the human chromosome complement

1971 • 141 citations

E. coli σ Factor: A Positive Control Element in Phage T4 Development

1969 • 141 citations

Transcription of Nonrepeated DNA in Mouse Brain

1971 • 139 citations

Gene Amplification in the Oocyte Nucleus of Mutant and Wild-type Xenopus laevis

1968 • 139 citations

THE SINGLE-X NATURE OF SEX CHROMATIN IN MAN

1961 • 139 citations

Initiation of RNA Synthesis: the Function of σ in the Binding of RNA Polymerase to Promoter Sites

1970 • 138 citations

Reiteration Frequency of Haemoglobin Genes in the Duck

1972 • 137 citations

Architecture of the Chinese hamster metaphase chromosome

1971 • 136 citations

Deoxyribonucleic acid replication in synchronized cultured mammalian cells

1970 • 136 citations

Nuclear phosphoproteins. I. Isolation and characterization of a phosphoprotein fraction from calf thymus nuclei.

1969 • 136 citations

Populations of repeated DNA sequences in the human genome

1972 • 136 citations

The Synthesis of Acidic Nuclear Proteins in the Prereplicative Phase of the Isoproterenol-stimulated Salivary Gland

1970 • 135 citations

Bacteriophage Sigma Factor for RNA Polymerase

1969 • 135 citations

New Controlling Element in the Lac Operon of E. coli

1968 • 135 citations

Chromosome Fibers from an Interphase Nucleus

1963 • 135 citations

Radiosensitivity of cells of Chinese hamster in vitro in relation to the cell cycle

1962 • 134 citations

Kinetics of Deoxyribonuclease Action on Chromosomes

1963 • 133 citations

Possible Mechanisms of X Chromosome Inactivation

1971 • 133 citations

Physical Studies of the Molecular Structure of Deoxyribose Nucleic Acid and Nucleoprotein

1956 • 133 citations

Analysis of the human karyotype using a reassociation technique

1971 • 133 citations

Sedimentation properties of the newly synthesized RNA from isolated nuclear components of Chironomus tentans salivary gland cells

1967 • 132 citations

Heterochromatin recognition with fluorochromes

1970 • 132 citations

Localisation of reiterated nucleotide sequences in Drosophila and mouse by in situ hybridisation of complementary RNA

1970 • 132 citations

On the cross-section Structure of deoxyribonucleic acid in solution

1971 • 131 citations

Origin of Satellite DNA

1971 • 130 citations

A Structural Comparison of Different Lysine-rich Histones of Calf Thymus

1966 • 130 citations

Template activity of DNA is restricted in chromatin

1966 • 129 citations

DNA-RNA hybridization in vast DNA excess.

1971 • 129 citations

Genetic Control and Regulation of Developmental Pathways

1964 • 128 citations

Interaction of lysine-rich histones and DNA

1969 • 127 citations

Karyotype analysis utilizing differentially stained constitutive heterochromatin of human and murine chromosomes

1971 • 126 citations

Sequence diversity of polytene chromosome DNA from Drosophila hydei

1971 • 126 citations

Satellite DNA in Constitutive Heterochromatin of the Guinea Pig

1970 • 126 citations

Turnover of nuclear and cytoplasmic ribonucleic acid in two types of animal cell, with some further observations on the nucleolus

1959 • 125 citations

Isolated mammalian metaphase chromosomes

1967 • 125 citations

Evidence for two DNA-dependent RNA polymerase activities in isolated rat-liver nuclei

1964 • 124 citations

On the structure of nucleohistone

1971 • 124 citations

The isolation of complementary strands from a mouse DNA fraction.

1967 • 122 citations

ATP-Dependent and Cyclic AMP-Dependent Activation of Rat Adipose Tissue Lipase by Protein Kinase from Rabbit Skeletal Muscle

1970 • 121 citations

Stepwise removal of protein from a deoxyribonucleoprotein complex and de-repression of the genome

1966 • 121 citations

The mutagenic action of caffeine in higher organisms.

1968 • 121 citations

The structure of nucleohistones and nucleoprotamines

1963 • 120 citations

A chemically-induced variegated-type position effect in the mouse

1961 • 120 citations

The Nature and Biosynthesis of Nuclear Ribonucleic Acids

1967 • 120 citations

Optical absorbance and optical rotatory dispersion studies on calf thymus nucleohistone

1969 • 120 citations

THE CHEMICAL COMPOSITION OF ISOLATED CHROMOSOMES

1947 • 120 citations

Conformation of deoxyribonucleic acid in chromatin: A circular dichroism study

1970 • 119 citations

Human Oögenesis

1962 • 118 citations

Proteins binding to DNA and their Relation to Growth in Cultured Mammalian Cells

1971 • 117 citations

Sequence Homology and Role of Cysteine in Plant and Animal Arginine-rich Histones

1968 • 117 citations

Nuclear phosphoproteins

1969 • 117 citations

How Different are the DNAs from Related Animals?

1968 • 117 citations

ROLE OF CHROMATIN IN ESTROGEN ACTION IN THE UTERUS, II. HORMONE-INDUCED SYNTHESIS OF NONHISTONE ACIDIC PROTEINS WHICH RESTORE HISTONE-INHIBITED DNA-DEPENDENT RNA SYNTHESIS

1969 • 117 citations

Breaks in DNA stimulate Transcription by Core RNA Polymerase

1969 • 116 citations

Whole mount electron microscopy of meiotic chromosomes and the synaptonemal complex

1970 • 115 citations

THE RELATIVE MUTABILITIES OF DNA IN REGIONS OF THE X CHROMOSOME OF DROSOPHILA MELANOGASTER

1965 • 115 citations

The Ultrastructure of Genetic Systems in Prokaryotes and Eukaryotes

1963 • 115 citations

Studies on the intranuclear distribution and properties of mouse satellite DNA

1968 • 115 citations

Simplicity of Mammalian Regulatory Systems inferred by Single Gene Determination of Sex Phenotypes

1971 • 114 citations

A demonstrable local and geometric increase in the chromosomal DNA ofChironomus

1965 • 113 citations

Unstable nuclear RNA synthesis following estrogen stimulation

1970 • 113 citations

Mitochondrial RNA Polymerase from Neurospora crassa

1971 • 113 citations

Distribution of DNA replicator sites in mammalian nuclei after different methods of cell synchronization

1970 • 113 citations

Effects of low salt concentration on structural organization and template activity of chromatin in chicken erythrocyte nuclei*

1971 • 112 citations

The Eukaryotic Chromosome

1970 • 112 citations

On the association between DNA and membrane in bacteria

1966 • 112 citations

Control of Template Specificity of E. coli RNA Polymerase by a Phage-coded Protein

1969 • 110 citations

SPATIAL RELATIONSHIPS IN THE REPLICATION OF CHROMOSOMAL DNA

1965 • 110 citations

Restoration of histone-inhibited DNA-dependent RNA synthesis by acidic chromatin proteins

1968 • 110 citations

SV40-Specific RNA in the Nucleus and Polyribosomes of Transformed Cells

1970 • 109 citations

Purification and DNA-Binding Properties of the Catabolite Gene Activator Protein

1971 • 109 citations

Electron-microscope observations on the organization of hetero-chromatin in certain cells

1968 • 109 citations

THE RELATION BETWEEN DNA SYNTHESIS AND CHROMOSOME STRUCTURE AS RESOLVED BY X-RAY DAMAGE

1963 • 108 citations

Chromosome fibers studied by a spreading technique

1966 • 108 citations

Variations in the DNA from Two Rodent Families (Cricetidae and Muridae)

1970 • 106 citations

PROTEIN SYNTHESIS AND RNA SYNTHESIS DURING MITOSIS IN ANIMAL CELLS

1963 • 106 citations

Recognition of Nucleotide Sequences

1969 • 106 citations

Soluble Complexes between Steroid Hormones and Target-Tissue Receptors Bind Specifically to Target-Tissue Chromatin

1971 • 103 citations

HÆMOGLOBIN TAK: A VARIANT WITH ADDITIONAL RESIDUES AT THE END OF THE β-CHAINS

1971 • 103 citations

The differentiation of the sex chromosomes ofDrosophila into genetically active and inert regions

1932 • 103 citations

Positive Control of Transcription by a Bacteriophage Sigma Factor

1970 • 103 citations

DNA Chain Growth: In Vivo and in Vitro Synthesis in a DNA Polymerase-negative Mutant of E. coli

1970 • 103 citations

MOLECULAR CHARACTERIZATION OF THE DROSOPHILA GENOME

1969 • 102 citations

Characterization of rapidly labeled ribonucleic acid of animal cells in culture

1965 • 101 citations

Chromosomal Distribution of Rapidly Reannealing DNA in Drosophila melanogaster

1970 • 101 citations

Proteins of interphase and metaphase chromosomes compared

1970 • 101 citations

Control of RNA synthesis in Escherichia coli

1968 • 99 citations

CHROMOSOME DUPLICATION AND STRUCTURE AS DETERMINED BY AUTORADIOGRAPHY

1963 • 99 citations

Portrait of a gene

1969 • 99 citations

Phosphorylation of Ribosome-Associated Protein by an Adenosine 3′:5′-Cyclic Monophosphate-Dependent Protein Kinase: Location of the Microsomal Receptor and Protein Kinase

1971 • 98 citations

Some properties of mammalian DNA-like RNA isolated by chromatography on methylated bovine serum albumin-kieselguhr columns

1966 • 96 citations

CHROMOSOMIN, A PROTEIN CONSTITUENT OF CHROMOSOMES

1943 • 96 citations

Isolation of the complementary strands of a human satellite DNA

1968 • 95 citations

Chronic Illness in Young People

1964 • 95 citations

Isolation and Biochemical Characteristics of the Nuclear Envelope

1969 • 95 citations

The Basic Proteins of Cell Nuclei

1965 • 94 citations

Tumour Immunity induced in Mice with Cell-free Homogenates of Influenza Virus-infected Tumour Cells

1971 • 94 citations

Polyribosome Disaggregation during Metaphase

1966 • 94 citations

STRANDEDNESS OF VICIA FABA CHROMOSOMES AS REVEALED BY ENZYME DIGESTION STUDIES

1965 • 94 citations

THE BASE COMPOSITION OF RIBONUCLEIC ACID IN LAMPBRUSH CHROMOSOMES, NUCLEOLI, NUCLEAR SAP, AND CYTOPLASM OF TRITURUS OOCYTES

1963 • 94 citations

Cyclization of eucaryotic deoxyribonucleic acid fragments

1970 • 94 citations

Fine structure of kinetochore in Indian muntjac

1971 • 94 citations

Heterochromatin of the Indian muntjac

1971 • 93 citations

Control of Transcription in Bacteria

1971 • 93 citations

Nucleotide Sequence Homologies in Nuclear and Cytoplasmic Ribonucleic Acid from Rat Liver and Hepatomas

1968 • 92 citations

Heterochromatin in mammals.

1967 • 91 citations

The chromosomal localization of a heavy satellite DNA in the testis of Plethodon c. cinereus

1971 • 90 citations

Evidence for stable attachment of DNA to membrane at the replication origin of Escherichia coli

1970 • 90 citations

Nuclear factors affecting radiosensitivity. I. The influence of nuclear size and structure, chromosome complement, and DNA content.

1961 • 90 citations

Satellite DNA associated with heterochromatin in Rhynchosciara

1971 • 89 citations

The heterogeneity of thymine methyl group origin in DNA pyrimidine isostichs of developing sea urchin embryos.

1967 • 89 citations

The heterogeneity of the non‐histone chromatin proteins from mouse tissues

1971 • 89 citations

RNA Polymerase Mutants blocked in Sporulation

1970 • 88 citations

Buoyant density of DNA synthesized at different stages of the S phase of mouse L cells

1971 • 87 citations

Isolated mammalian metaphase chromosomes

1969 • 87 citations

Involvement of a Phage T4 σ Factor and an Anti-terminator Protein in the Transcription of Early T4 Genes in vivo

1970 • 87 citations

Satellite DNA in calf heterochromatin

1971 • 87 citations

Spectroscopic studies of the conformations of histones and protamine

1967 • 87 citations

Comparative DNA Renaturation Kinetics in Amphibians

1971 • 87 citations

High molecular weight nonribosomal-type nuclear RNA and cytoplasmic messenger RNA in HeLa cells.

1966 • 86 citations

RNA Polymerase σ-Factor and the Selection of Initiation Site

1970 • 86 citations

Altered conformational effects of phosphorylated lysine-rich histone (f-1) in f-1-deoxyribonucleic acid complexes. Circular dichroism and immunological studies

1971 • 85 citations

Nuclear and Cytoplasmic Messenger-like RNA and Their Relation to the Active Messenger RNA in Polyribosomes of HeLa Cells

1970 • 85 citations

Tissue specificity of non‐histone chromatin phosphoproteins

1970 • 84 citations

REVERSAL OF HETEROCHROMATIZATION AND THE ACTIVITY OF THE PATERNAL CHROMOSOME SET IN THE MALE MEALY BUG

1967 • 84 citations

Unexpectedly Large Size of Globin Messenger Ribonucleic Acid

1971 • 84 citations

DNA replication in chinese hamster cells: Evidence for a single replication fork per replicon

1971 • 84 citations

A cycloid model for the chromosome

1967 • 84 citations

Transcription of Nonrepeated DNA in Neonatal and Fetal Mice

1971 • 83 citations

Evolution of sex-chromosomes and formation of W-chromatin in snakes

1971 • 83 citations

Localization of the replication point of mammalian cell DNA at the membrane

1971 • 83 citations

Heterogeneity and Polymorphism in Chicken Erythrocyte Histone Fraction V

1971 • 83 citations

The relative abllity of reconstituted nucleohistones to allow DNA-dependent RNA synthesis

1963 • 82 citations

The Role of Sigma Subunit in Template Site Selection by E. coli RNA Polymerase

1970 • 82 citations

SALIVARY CHROMOSOME BANDS AND THE FREQUENCY OF CROSSING OVER IN DROSOPHILA MELANOGASTER

1971 • 82 citations

Phosphorylation of mouse ascites tumor cell lysine-rich histone

1970 • 82 citations

Nicotine Hydrogen Tartrate: Effect on Essential Fatty Acid Deficiency in Mature Pigs

1969 • 82 citations

Protein catabolism in thymus nuclei

1967 • 82 citations

THE NATURE OF HETEROCHROMATIN

1947 • 81 citations

SOME OBSERVATIONS ON PROTEIN METABOLISM IN CHROMOSOMES OF NON-DIVIDING CELLS

1955 • 80 citations

Characterization of RNA in fractions of calf thymus chromatin

1971 • 80 citations

The Structure and Replication of Eukaryotic Chromosomes

1970 • 80 citations

A satellite DNA isolated from human tissues

1967 • 80 citations

Studies on the nature of replicating DNA of HeLa cells

1969 • 79 citations

Density gradient analysis of newly replicated DNA from synchronized mouse lymphoma cells

1971 • 79 citations

Structure of nucleohistone. I. Hydrodynamic behaviour.

1966 • 79 citations

THE FINE STRUCTURE AND CHEMICAL COMPOSITION OF NUCLEI DURING SPERMIOGENESIS IN THE HOUSE CRICKET

1966 • 78 citations

Chromosome splitting as revealed by combined X-ray and labeling experiments

1964 • 78 citations

The arrangement of DNA in human chromosomes, as investigated by quantitative electron microscopy.

1969 • 78 citations

On the process of cellular division in Escherichia coli

1971 • 77 citations

Chromosomal ribonucleic acid of rat ascites cells

1969 • 77 citations

A Study of the Multiplicity of Lysine-rich Histones

1969 • 77 citations

The fine structure of isolated chromosomes

1965 • 77 citations

Active Form of Two Coliphage Repressors

1970 • 76 citations

DNA of mammalian and avian heterochromatin

1972 • 76 citations

Inhibition of RNA Polymerase by ppGpp, a Nucleotide Accumulated during the Stringent Response to Amino Acid Starvation in E. coli

1970 • 76 citations

Cytological characteristics of protein and nucleoprotein fractions of cell nuclei

1959 • 76 citations

RNA transcription from nonrepetitive DNA in the mouse

1971 • 75 citations

Nuclear Ribonucleic Acid

1963 • 75 citations

Spatial Distribution of Old and New Chromatid Sub-units and Frequency of Chromatid Exchanges in Induced Human Lymphocyte Endoreduplications

1967 • 75 citations

Specific Inhibitors of the Three RNA Polymerases from the Aquatic Fungus Blastocladiella emersonii

1971 • 74 citations

CHROMOSOME CONSTITUTION AND BEHAVIOR IN EVERSPORTING AND MOTTLING IN DROSOPHILA MELANOGASTER

1934 • 74 citations

DNS-Reduplikationsmuster bei den Riesen-Geschlechtschromosomen von Microtus agrestis

1965 • 74 citations

Association of nuclear membrane fragments with metaphase and anaphase chromosomes as observed by whole mount electron microscopy

1970 • 72 citations

ISOLATION OF METAPHASE CHROMOSOMES FROM HELA CELLS

1966 • 71 citations

Testosterone-“Regulon” in the Mouse Kidney

1971 • 71 citations

A Partial Sequence of Nuclear Events in Regenerating Rat Liver

1972 • 71 citations

The Structure of Chromatin

1971 • 71 citations

The genetical activity of heterochromatin

1944 • 71 citations

Solubilization and Characterization of the Residual Proteins of the Cell Nucleus

1966 • 70 citations

THE DETECTION OF INERT GENES

1941 • 70 citations

Membrane Association by Bacteriophage λ DNA: Possible Direct Role of Regulator Gene N

1969 • 70 citations

Association of DNA replication with the nuclear membrane of HeLa cells

1972 • 69 citations

Regulation of chromosome replication and segregation in bacteria.

1966 • 69 citations

Buoyant densities of DNA of mammals

1970 • 69 citations

DNA Synthesis associated with the Inner Membrane of the Nuclear Envelope

1971 • 69 citations

The intranuclear localization of two DNA-dependent RNA polymerase activities.

1967 • 69 citations

Selective dissociation of histones from chromatin by sodium deoxycholate

1971 • 69 citations

The release of high molecular weight DNA from a mammalian cell (L-5178Y). Attachment of the DNA to the nuclear membrane.

1971 • 68 citations

Organization and control in prokaryotic and eukaryotic cells.

1970 • 68 citations

Lac Repressor Binding to DNA not containing the Lac Operator and to Synthetic Poly dAT

1970 • 68 citations

Studies of fractionated HeLa cell metaphase chromosomes

1967 • 68 citations

The amino acid sequence of the third component of clupeine

1967 • 68 citations

COMPARATIVE STUDIES ON X-AUTOSOME TRANSLOCATIONS IN THE MOUSE. II. INACTIVATION OF AUTOSOMAL LOCI, SEGREGATION, AND MAPPING OF AUTOSOMAL BREAKPOINTS IN FIVE T(X;1)'S

1970 • 68 citations

Fractions of HeLa DNA differing in their content of guanine + cytosine

1969 • 68 citations

HIGH SEQUENCE DIVERSITY IN THE RNA SYNTHESIZED AT THE LAMPBRUSH STAGE OF OÖGENESIS

1969 • 67 citations

Limited molecular heterogeneity of plant histones

1969 • 67 citations

A study of DNA nucleoprotein gels and the residual protein of isolated cell nuclei

1964 • 67 citations

Mismatching and the Reassociation Rate of Mouse Satellite DNA

1971 • 67 citations

Effects of Sequence Divergence on the Reassociation Properties of Repetitive DNAs

1971 • 66 citations

Model for Quantitative and Qualitative Control of mRNA Translation in Eukaryotes

1970 • 66 citations

Proteins of chromatin in template restriction

1971 • 66 citations

Different satellite deoxyribonucleic acids of guinea pig and ox

1970 • 65 citations

OBSERVATIONS ON THE UPTAKE OF TRITIATED THYMIDINE IN THE PRONUCLEI OF FERTILIZED SAND DOLLAR EMBRYOS

1961 • 65 citations

The heteropycnosis of sex chromosomes and its interpretation in terms of spiral structure

1940 • 65 citations

Acidic proteins of mammalian nuclei: isolation and characterization.

1968 • 64 citations

Changes in nuclear and cytoplasmic RNA in regenerating mouse liver.

1967 • 64 citations

Human chromosome fibers

1970 • 64 citations

A T4-Induced RNA Polymerase Subunit Modification

1970 • 64 citations

A COMPARISON BETWEEN HETEROGENEOUS NUCLEAR RNA AND POLYSOMAL MESSENGER RNA IN HELA CELLS BY RNA-DNA HYBRIDIZATION

1970 • 64 citations

Turnover of nucleic acids in a non-multiplying animal cell

1959 • 64 citations

Affinity: A New Genetic Phenomenon in the House Mouse: Evidence from Distant Crosses

1953 • 64 citations

Structural Patterns and the Functional Organization of Chromosomes

1964 • 63 citations

Differential Staining Patterns of Heterochromatin in Man

1971 • 63 citations

Structure of nucleohistone

1966 • 63 citations

Medicine and the Law

1959 • 63 citations

The relationship between nuclear and cytoplasmic ribonucleic acid

1962 • 62 citations

Study of the chromatin acidic proteins of rat liver: Heterogeneity and complex formation with histones

1968 • 62 citations

Timing of DNA synthesis in ovarian oocyte nuclei and pronuclei of the mouse

1959 • 62 citations

HISTONES OF GENETICALLY ACTIVE AND INACTIVE CHROMATIN

1967 • 62 citations

THE HUMAN CHROMOSOME

1969 • 62 citations

Chemistry and biology of the histones.

1970 • 62 citations

Continued synthesis of non-histone chromosomal proteins during mitosis

1970 • 62 citations

N-terminal acetyl-peptides from two calf thymus histones

1968 • 61 citations

Changes in chromosomal DNA replication patterns in developing frog embryos

1970 • 61 citations

Molecular complementarity between nuclear DNA and organ-specific chromosomal RNA.

1967 • 61 citations

Related base sequences in the DNA of simple and complex organisms. VI. The extent of base sequence divergence among the DNAs of various rodents

1970 • 60 citations

Observations on the modification in size and shape of chromosomes due to technical procedure

1960 • 60 citations

HETEROCHROMATY IN CHROMOSOMES DURING THEIR CONTRACTION PHASE

2010 • 60 citations

Mechanism of Chromosome Pairing during Meiosis

1970 • 60 citations

Renaturation and isolation of single strands from the nuclear DNA of the guinea pig

1969 • 60 citations

Genetic control over the inactivation of autosomal genes attached to the X-chromosome

1965 • 60 citations

The effects of acidic proteins and RNA on the histone inhibition of the DNA-dependent RNA synthesis in vitro

1969 • 60 citations

Whole-mount electron microscopy of the centromere region of metacentric and telocentric mammalian chromosomes

1970 • 60 citations

Thymus deoxyribonucleoprotein III. Sedimentation behaviour

1963 • 60 citations

DNA polymerase from rat liver chromosomal proteins I. Partial purification and general characteristics

1969 • 59 citations

Purification and properties of a neutral protease from calf thymus nuclei

1968 • 59 citations

Position of Labelled Chromatids in Diplochromosomes of Endo-reduplicated Cells after Uptake of Tritiated Thymidine

1966 • 59 citations

Chromosomal RNA of calf thymus chromatin

1969 • 59 citations

The Duration of Replication of the Inactive X Chromosome in Humans Based on the Persistence of the Heterochromatic Sex Chromatin Body During DNA Synthesis

1967 • 59 citations

VARIATIONS IN CYTOCHEMICAL PROPERTIES OF CELL NUCLEI

1958 • 58 citations

RNA Polymerase and T4 Development

1970 • 58 citations

Conformational analysis of DNA-poly-l-lysine complexes by optical rotatory dispersion

1968 • 58 citations

A lipoprotein of rat liver nuclei

1953 • 57 citations

Activation of transcription in vitro from chromatin by non-histone proteins

1970 • 57 citations

Inhibition of DNA polymerase by histones

1964 • 57 citations

Transcription 1970: A Summary

1970 • 57 citations

Studies on nuclea proteins I. Observations on the tissue and species specificity of the moderately lysine-rich histone fraction 2b☆

1966 • 56 citations

Isolation of the 434 Phage Repressor

1969 • 56 citations

On the structure of tumor cell nuclei

1962 • 56 citations

Nature and Self-Regulated Synthesis of the Repressor of the hut Operons in Salmonella typhimurium

1971 • 55 citations

Control of DNA Replication by Membrane

1968 • 55 citations

Strandedness of Chromosomes

1969 • 55 citations

The distribution of rapidly hybridizing RNA sequences in heterogeneous nuclear RNA and mRNA from hela cells

1970 • 55 citations

Buoyant Density and Satellite Composition of DNA of Mouse Heterochromatin

1971 • 54 citations

Temperaturbedingte Ausbildung von Spezialsegmenten an Chromosomenenden

1939 • 54 citations

The organization and ultrastructure of male meiotic chromosomes in oncopeltus fasciatus

1965 • 54 citations

Shift in buoyant density of DNA during the synthetic period and its relation to euchromatin and heterochromatin in mammalian cells

1971 • 53 citations

Fine structure of lampbrush chromosomes.

1965 • 53 citations

Amplication of ribosomal cistrons in the heterochromatin of acheta.

1969 • 53 citations

Advances in cell and molecular biology

1971 • 53 citations

Distribution of DNA replicator sites in mammalian nuclei

1972 • 53 citations

Repeated Segments of DNA

1970 • 53 citations

Chromosome structure in tradescantiae I. Methods and morphology

1932 • 53 citations

Computerized chromosome identification by aid of the quinacrine mustard fluorescence technique

2009 • 52 citations

The Factor: Termination and Anti-termination in Lambda

1970 • 52 citations

Association between the chromosome and the cytoplasmic membrane in Bacillussubtilis

1969 • 52 citations

Species Differences in Animal Deoxyribonucleic Acids as revealed by Equilibrium Sedimentation in Density Gradients

1962 • 51 citations

X-chromosome behavior in germ and somatic cells of Rattus norvegicus

1961 • 51 citations

Nuclear morphology and the ultra-structural localization of deoxyribonucleic acid synthesis during interphase

1969 • 51 citations

THE NATURE OF THE PROTEINS OF CELLULAR NUCLEI

1942 • 50 citations

Studies on the role of histones in the structure of chromatin

1971 • 50 citations

Subchromatid structure of chromosomes in the living state

1965 • 50 citations

Light satellite-band DNA in mouse cells infected with polyoma virus

1970 • 49 citations

Distinct RNA Synthesis Systems of the HeLa Cell

1970 • 49 citations

Replicative heterogeneity of mammalian DNA

1972 • 49 citations

Condensation of chromosomes onto the nuclear membrane during prophase

1970 • 49 citations

Studies on the role of histones in relation to the template activity and precipitability of chromatin at physiological ionic strengths

1971 • 49 citations

THE MEIOTIC CHROMOSOMES OF THE MALE LLAVEIELLA TAENECHINA MORRISON (COCCIDAE) AND THE QUESTION OF THE TERTIARY SPLIT

1940 • 49 citations

DNA SYNTHESIS AND CHROMOSOMAL MORPHOLOGY OF CHINESE HAMSTER CELLS CULTURED IN MEDIA CONTAINING N-DEACETYL-N-METHYLCOLCHICINE (COLCEMID)11Supported in part by Grant DRG-269 from Damon Runyon Memorial Fund for Cancer Research, and Grant E-286 from American Cancer Society, Inc.

1964 • 49 citations

Structure of deoxyribonucleoprotein as revealed by its binding to polylysine

1970 • 49 citations

Proton Magnetic Resonance Studies of the Interactions of Histones F1 and F2B with DNA

1971 • 48 citations

The amino acid sequence of the second component of clupeine

1966 • 47 citations

Regulation of Gal Messenger Ribonucleic Acid Synthesis in Escherichia coli by 3',5'-Cyclic Adenosine Monophosphate

1971 • 47 citations

DNA Content and Size of Sex Chromatin Positive Female Nuclei During the Cell Cycle

1967 • 47 citations

Replication of chromosomal and cytoplasmic DNA during mitosis and meiosis in the eucaryoteChlamydomonas reinhardi

1967 • 47 citations

Calf thymus histone III: Sequences of the amino- and carboxyl-terminal regions and of the regions containing lysyl residues modified by acetylation and methylation

1970 • 47 citations

XV.—“Ectopic” Pairing and the Distribution of Heterochromatin in the X-Chromosome of Salivary Gland Nuclei of Drosophila melanogaster

1946 • 47 citations

The release of high molecular weight DNA from a mammalian cell (L5178Y)

1971 • 47 citations

Isolation and characterization of human metaphase chromosomes.

1966 • 47 citations

Comparison of Histones Obtained from Mammary Gland at Different Stages of Development and Lactation

1968 • 47 citations

Biochemistry of histones and the cell cycle

1963 • 46 citations

Buoyant density of DNA synthesized at different stages of S phase in Chinese hamster cells

1971 • 46 citations

RNA replication by nuclear satellite DNA in different mouse cells

1968 • 46 citations

Protein catabolism in thymus nuclei

1967 • 44 citations

Nuclear Proteins of Neoplastic Cells

1964 • 44 citations

Nuclear phosphoproteins. II. Metabolism of exogenous phosphoprotein by intact nuclei.

1969 • 44 citations

The dissociation of chicken erythrocyte deoxyribonucleoprotein and some properties of its partial nucleoproteins

1970 • 44 citations

B. Chromosomes and genes - Fine structure of chromosomes

1966 • 43 citations

The relationship of isolated chromosome fibers to the fibers of the embedded nucleus

1967 • 43 citations

Genetic inactivity of heterochromatin and heteropycnosis in Microtus agrestis

1970 • 43 citations

Sex Chromatin, Nuclear Size and the Cell Cycle

1967 • 42 citations

The ultrastructure and strandedness of chromosomes from two species of Vicia

1968 • 42 citations

Chromatin and histones in mealy bug cell explants: activation and decondensation of facultative heterochromatin by a synthetic polyanion

1971 • 42 citations

Rho Factor Function in T4 RNA Transcription

1970 • 42 citations

Fine Structure of Heterochromatin in Certain Cell Nuclei

1967 • 42 citations

THE INACTIVE X CHROMOSOME

1966 • 42 citations

Nonreplication of heterochromatic chromosomes in a mealy bug, Planococcus citri (Coccoidea: Homoptera)

1966 • 42 citations

Rates of DNA synthesis in heterochromatic and euchromatic segments of the chromosome Complements of two rodents

1969 • 41 citations

Controlling elements in the mouseX-chromosome III. Influence upon both parts of anXdivided by rearrangement

1970 • 41 citations

Nuclear phosphoproteins

1969 • 41 citations

The separation of nascent deoxyribonucleic acid from the remainder of the cellular deoxyribonucleic acid

1962 • 41 citations

The Methylation of the Histones of Rat Liver Nucleiin vitro

1967 • 41 citations

Eversporting as a Function of the Y-Chromosome in Drosophila Melanogaster

1933 • 40 citations

STRUCTURE OF THE CHROMATIN IN SEA URCHIN SPERM

1965 • 40 citations

Studies of microchromosomes and a G-C rich DNA satellite in the quail

1970 • 40 citations

Nucleohistone Composition in Stationary and Division Synchronized Tetrahymena Cultures^*

1966 • 40 citations

Association of Chromosomal RNA with Repetitive DNA

1971 • 40 citations

Mechanisms of Synthesis and Control of Protein and Ribonucleic Acid Synthesis in the Cell Nucleus

1963 • 40 citations

Mechanism of Inhibitory Action of Histones on DNA Template Activity in vitro

1970 • 40 citations

Planning Complex Building Systems

1971 • 40 citations

Phosphoproteins from calf-thymus nuclei: Studies on the method of isolation

1969 • 40 citations

ELECTRON MICROSCOPY OF THE MACRONUCLEUS OF EUPLOTES EURYSTOMUS

1962 • 40 citations

An alkaline deoxyribonuclease from rat liver non-histone chromatin proteins

1969 • 39 citations

The effect of DNA-histone interactions on the biosynthesis of DNA in vitro

1964 • 39 citations

Identical Linear Order of Chromosomes in Both Gametes of the Acoel Turbellarian Polychoerus carmelensis: A Preliminary Note

1970 • 39 citations

Histones and Gene Control

1970 • 39 citations

Ribosomal RNA Synthesis and RNA Polymerase

1970 • 39 citations

The time of DNA replication in the cell cycle in relation to RNA synthesis in frog embryos

1971 • 39 citations

Differential fluorescent staining of Drosophila chromosomes with quinacrine mustard

1971 • 39 citations

RNA synthesis in Taper hepatoma and mouse-liver cells

1969 • 39 citations

The desoxyribonucleoprotein of sea urchin sperm II. Properties

1953 • 39 citations

Electron Microscope observations on Mitotic Chromosomes

1965 • 38 citations

THE STRUCTURE OF INTRALOCUS DUPLICATION AND DEFICIENCY CHROMOSOMES PRODUCED BY RECOMBINATION IN DROSOPHILA MELANOGASTER, WITH EVIDENCE FOR POLARIZED PAIRING

1964 • 38 citations

EVIDENCE FOR CONTROL OF THE RATE OF NUCLEAR DNA SYNTHESIS BY THE NUCLEAR MEMBRANE IN EUKARYOTIC CELLS

1969 • 38 citations

Polytene Chromosome Structure in Relation to the “Folded Fibre” Concept

1966 • 38 citations

PSEUDO-ALLELISM AT THE VERMILION LOCUS IN DROSOPHILA MELANOGASTER

1954 • 38 citations

A DNA-lipid protein containing material isolated from calf thymus nuclear chromatin

1968 • 38 citations

Some evidence concerning the “Mutational load” in inbred strains of mice

1959 • 38 citations

RESTRICTED REJOINING OF CHROMOSOMAL SUBUNITS IN ABERRATION FORMATION: A TEST FOR SUBUNIT DISSIMILARITY

1969 • 38 citations

H3-thymidine Autoradiographic Studies on the Heteropycnosis, Heterochromatin and Euchromatin in Spiranthes sinensis

1965 • 38 citations

Fine structure of the synaptonemal complex*Regular and stereo electron microscopy of deoxyribonuclease-treated whole mount preparations

1971 • 37 citations

Can Geomagnetic Polarity Intervals be Classified ?

1971 • 37 citations

Frequency of sex-chromatin-positive cells in the logarithmic and postlogarithmic growth phases of human cells in tissue culture

1962 • 36 citations

Asynchrony of DNA replication and mitotic spiralization along heterochromatic portions of Chinese hamster chromosomes

1968 • 35 citations

Binding of termination factor RHO to RNA polymerase and DNA

1971 • 35 citations

Related base sequences in the DNA of simple and complex organisms. III. Variability in the base sequence of the reduplicated genes for ribosomal RNA in the rabbit

1968 • 35 citations

The protein composition of nuclei during spermiogenesis in the leopard frog, Rana pipiens

1970 • 35 citations

THE ANALYSIS OF CELL REPRODUCTION*

1960 • 35 citations

TEMPERATURE-INDUCED DIFFERENTIAL CONTRACTION IN THE SOMATIC CHROMOSOMES OF TRILLIUM ERECTUM L.

1944 • 35 citations

A DNA-Acrylamide Gel Column for Analyzing Proteins That Bind to DNA, I. DNA Polymerase

1970 • 34 citations

The DNA content of cold-treated chromosomes

1964 • 34 citations

Segregation of chromosomal DNA in chinese hamster fibroblasts in vitro

1969 • 34 citations

Puffing and Histone Acetylation in Polytene Chromosomes

1970 • 33 citations

DNA-associated acidic proteins

1968 • 33 citations

Transcription of Ribosomal, Heterogeneous Nuclear, and Messenger RNA in Eucaryotes

1970 • 33 citations

HYBRIDIZATION OF CHROMOSOMAL RNA TO NATIVE DNA

1969 • 33 citations

The splitting of human chromosomes into chromatids in the absence of either DNA or protein synthesis

1969 • 32 citations

Molecular biology of sex differentiation1

2009 • 32 citations

Whole-mount electron microscopy of chromatin and membranes in bull and human sperm heads

1968 • 32 citations

Heterochromatin, colchicine, and karyotype

1965 • 32 citations

Experimental changes in the width of the chromatin fibers from chicken erythrocytes

1971 • 32 citations

Puff RNA in Polytene Chromosomes

1970 • 32 citations

An RNA-histone complex in mammalian cells: the isolation and characterization of a new RNA species.

1966 • 31 citations

Studies on the Relationship of mRNA to Heterogeneous Nuclear RNA in Mammalian Cells

1970 • 31 citations

Studies on the composition of nuclear residual proteins from rat liver and walker 256 carcinosarcoma

1964 • 31 citations

AN ANALYSIS OF HETEROCHROMATIN IN MAIZE ROOT TIPS

1967 • 31 citations

THE STRANDEDNESS OF MEIOTIC CHROMOSOMES FROM ONCOPELTUS

1966 • 31 citations

Protein synthesis in nuclear residual protein

1965 • 31 citations

The structure of metaphase chromosomes

1970 • 30 citations

Localization and Regulation of Two NAD Nucleosidases in Ehrlich Ascites Cells

1968 • 30 citations

Effects of ?-amanitin on lampbrush chromosomes

1971 • 30 citations

Isolation of the Arginine Repressor in Escherichia coli

1970 • 30 citations

Alternative Model for Gene Amplification

1971 • 30 citations

NEW EVIDENCE ON THE TELOPHASE SPLIT IN TODEA BARBARA

1945 • 30 citations

Further studies of DNA-nucleoprotein gels and residual protein of isolated cell nuclei

1968 • 29 citations

Adenosine 3′,5′-Monophosphate Increases Capacity for RNA Synthesis in Rat Liver Nuclei

1971 • 29 citations

Stimulation of nuclear protein synthesis in rat liver after phenobarbital administration

1970 • 29 citations

Partial Purification of a DNA-polymerase from the Non-histone Chromatin Proteins of Rat Liver

1967 • 29 citations

Origin and evolution of Parthenogenetic reproduction in the grasshopper Maraba virgo (Eumastacidae: Morabinae)

1968 • 29 citations

Circular Dichroism Study of the f2al Histone in the Presence of Polyvinyl-phosphate and DNA

1970 • 29 citations

DNA RNA Hybridisation of 9S messenger RNA for mouse globin

1970 • 29 citations

Optical rotatory dispersion of calf thymus deoxyribonucleoprotein

1966 • 28 citations

“Sub-chromatid” exchanges and the “folded fibre” model of chromosome structure

2009 • 28 citations

Studies of the nuclear residual proteins

1968 • 27 citations

A developmental study of constitutive heterochromatin in Microtus agrestis

1971 • 27 citations

Die Verteilung der Chromosomen auf die Tochterzellkerne multipolarer Mitosen in euploiden Gewebekulturen von Microtus agrestis

1969 • 27 citations

Changes in the fluorescence patterns of translocated Y chromosome segments in Drosophila melanogaster

1971 • 26 citations

The ultrastructure of chromatin fibers

1968 • 26 citations

Novel origin of some deoxyribonucleic acid thymine and its nonrandom distribution

1970 • 26 citations

Membrane pores and herpesvirus-type particles in negatively stained whole cells

1967 • 26 citations

Macronuclear chromatin structure in Euplotes

1967 • 25 citations

Developmental control of heterochromatization in coccids.

1969 • 25 citations

Characterization of nuclear RNA synthesis in

1971 • 25 citations

Whole mount electron microscopy of metaphase

1972 • 25 citations

Two Types of Heterochromatin in Drosophila Nebulosa

1946 • 25 citations

Somatic association of chromosomes in diploid and hexaploid Avena

1969 • 25 citations

Quantitative autoradiography of heterochromatin replication in Microtus agrestis

1970 • 25 citations

DNA synthesis by an insoluble chromatin fraction associated with the nuclear membrane of animal cells

1971 • 25 citations

Reaction of antinucleoside antibodies with human cells in vitro*1, *2

1971 • 25 citations

Structural Analysis of the Glycine-rich, Arginine-rich Histone

1969 • 24 citations

Histones of genetically active and inactive chromatin in mealy bugs

1970 • 24 citations

Species- and Tissue-specific Patterns of Phosphorylation of Very Lysine-rich Histones

1970 • 24 citations

Stimulation of chromation-bound RNA polymerase activity by a soluble factor

1970 • 24 citations

A Fraction of Newly Synthesized DNA of HeLa Cells

1967 • 24 citations

Nonhistone chromatin proteins from calf thymus and their role in DNA biosynthesis

1967 • 24 citations

Isolation of a terminal DNA-nucleotidyl transferase from calf thymus non histone chromatin proteins

1968 • 23 citations

DNA Replication in Antigen Stimulated Guinea-pig Lymph Node Cells

1970 • 23 citations

STUDIES ON NUCLEAR STRUCTURE AND FUNCTION IN TETRAHYMENA PYRIFORMIS

1970 • 23 citations

Chromosome replication and synthesis of non-histone proteins in giant polytene chromosomes

1968 • 23 citations

Molecular hybridization of Chinese hamster 5S, 4S and ?pulse-labelled? RNA in cytological preparations

1971 • 23 citations

THE EFFECT OF PREFIXATION ON THE DIAMETER OF CHROMOSOME FIBERS ISOLATED BY THE LANGMUIR TROUGH-CRITICAL POINT METHOD

1968 • 23 citations

Somatic Chromosome Structure (Observations with the light microscope)

1963 • 23 citations

Purification of the araC Protein

1971 • 22 citations

Control of Gene Transcription in T-even Bacteriophages: Alterations in RNA Polymerase accompanying Phage Infection

1969 • 22 citations

Gene products of Amphiuma: An amphibian with an excessive amount of DNA

1969 • 22 citations

Replication of Repetitious DNA and the S Period

1970 • 22 citations

DNA content of mitotically-active condensed chromosomes of Drosophila melanogaster

1971 • 22 citations

Polyphosphate groups at the 5′‐ends of nuclear dRNA fractions

1970 • 22 citations

Intranuclear distribution of satellite DNA from kangaroo rat

1970 • 21 citations

Reduplication of nuclear membranes in tissue-culture cells infected with guinea-pig cytomegalovirus.

1967 • 21 citations

FLUORESCENCE OF THE Y AND BARR BODY IN HUMAN INTERPHASE CELLS

1971 • 21 citations

Translocations between Eu- and heterochromatic chromosomes, and spermatocytes lacking a heterochromatic set in male mealy bugs

1970 • 21 citations

The ultrastructure of chromatin fibers

1968 • 21 citations

H<sup>3</sup>-Uridine Autoradiography of Human Chromosomes

1966 • 20 citations

'Affinity’

1955 • 20 citations

Properties of Escherichia coli deoxyribonucieoprotein as compared with the deoxyribonucleoprotein of higher organisms

1968 • 20 citations

Ultrastructure of the human chromosome fiber

1970 • 19 citations

Characterization of rapidly labelled rat liver ribonucleic acid showing high affinity for columns of methylated albumin on kieselguhr

1970 • 19 citations

END-TO-END, CHAIN-LIKE ASSOCIATIONS OF PAIRED PACHYTENE CHROMOSOMES OF CREPIS CAPILLARIS

1969 • 19 citations

Nucleoproteins in regulation of gene function.

1970 • 19 citations

Role of the residual nucleoprotein complex and acidic proteins of the cell nucleus in protein synthesis.

1965 • 19 citations

Protein synthesis in the cell nucleus. I. Amino acid incorporation into protein by the aggregate enzyme of Weiss

1966 • 19 citations

Structural Basis of Quantitative Variation in Nuclear DNA

1967 • 19 citations

A late replicating DNA protein complex from cells in meiotic prophase

1971 • 19 citations

X-ray diffraction study of the structure of nucleohistone and nucleoprotamines

1963 • 19 citations

Cytological Observations on the Strandedness of Mammalian Metaphase Chromosomes

1966 • 19 citations

ELECTRON MICROGRAPHIC STUDIES OF THE EXPANDED AND UNCOILED CHROMOSOMES FROM HUMAN LEUKOCYTES*

1964 • 19 citations

FLUORESCENCE AND Y TRANSLOCATION IN XX MALES

1971 • 19 citations

Formation and division of binucleated cells in kidney cell cultures of microtus agrestis

1968 • 18 citations

Hybridization studies with nucleic acids from murine plasma cell tumors

1970 • 18 citations

DNA Content of a Chromosome of Trillium erectum: Effect of Cold Treatment

1966 • 18 citations

Deoxyribonucleic acid-dependent protein synthesis in nuclear ribosome system in vitro

1966 • 18 citations

Early DNA Synthesis in the X-chromosome of <i>Pellia neesiana</i>

1970 • 17 citations

Asymmetry of heteropycnosis in tetraploid cells of a grasshopper

1970 • 17 citations

Isolabelling and Chromosome Strandedness

1971 • 17 citations

Studies on nuclear protein metabolism after infection of Ehrlich ascites cells with maus-elberfeld (ME) virus

1964 • 17 citations

Do half-chromatids exist?

1970 • 16 citations

RNA Synthesis in a Balbiani Ring in Chironomus tentans

1970 • 16 citations

THE REACTION OF TRILLIUM POLLENTUBE CHROMOSOMES

1953 • 16 citations

Pattern of DNA Replication in Chromosomes of the Dog

1966 • 16 citations

The C-terminal amino acids and sequences of calf and rat thymus histones

1969 • 16 citations

Struktur und Position der heterochromatischen Chromosomen in Interphasekernen von Microtus agrestis

1969 • 16 citations

New Evidence on the Telophase Split in Todea Barbara

1945 • 15 citations

Variation in glucose-6-phosphate dehydrogenase in relation to the growth phase and frequency of sex chromatin positive cells in cultures of fibroblasts from normal human females and a 48-XXXY male

1967 • 15 citations

Purification and properties of nuclear and cytoplasmic deoxyribonucleic acidlike ribonucleic acid from Ehrlich ascites cells

1969 • 15 citations

Isolation of an active complex of DNA-RNA-protein from nuclear residual fraction

1965 • 15 citations

The Acidic Nuclear Proteins

1965 • 15 citations

Occurrence of Plasmalogens in Lipides of Green Peas

1957 • 15 citations

Deoxyribonucleic acid sequences complementary to ribosomal ribonucleic acid in a crustacean

1969 • 15 citations

Heterochromatic Segments in Vicia revealed by Treatment with HCI–Acetic Acid

1968 • 13 citations

Research Article 9: Superrepressors of the lac Operon

1970 • 13 citations

THE STRANDEDNESS OF CHROMOSOMES: EVIDENCE FROM CHROMOSOMAL ABERRATIONS

1969 • 13 citations

Intranuclear accumulation of rna resembling the smaller ribosomal rna component

1970 • 13 citations

Molecular hybridization used to characterize the RNA synthesized by isolated bovine thymus nuclei.

1968 • 13 citations

Difference in the frequency of sex chromatin positive cells in DNA-synthetizing and non-synthetizing human cells in tissue cultures

1966 • 13 citations

Metabolic studies of histones and residual protein of rat liver nuclei

1968 • 12 citations

Nuclear ultrastructure of the transforming lymphocyte during inhibition of deoxyribonucleic acid synthesis with hydroxyurea

1969 • 12 citations

Simple purification of HeLa chromatin associated RNA

1970 • 12 citations

Chromosome and chromatid-type aberrations induced by cobalt60 irradiation and tritiated uridine in human leukocyte cultures

1970 • 12 citations

Antigenic Properties of a Homogeneous Tobacco Mosaic Virus–Hapten Conjugate

1970 • 12 citations

Simultaneous increase in labeling of nuclear RNA and of DNA associated acidic nuclear protein

1966 • 12 citations

EXAMINATION OF THE NUCLEOHISTONE FROM MOUSE LIVER AND INTESTINE FOR RNA COVALENTLY LINKED TO HISTONE

1966 • 12 citations

The surface and internal structure of metaphase chromatin

1970 • 11 citations

Adenosine 3′,5′-Monophosphate-Dependent Protein Kinase of Cultured Mammalian Cells

1971 • 11 citations

HALF-CHROMATID ABERRATIONS AND CHROMOSOME STRANDEDNESS

1970 • 11 citations

Related base sequences in the DNA of simple and complex organisms. IV. Evolutionary divergence of base sequence in mouse L-cell cytoplasmic and nucleus-restricted RNA

1970 • 11 citations

THE DIFFERENTIAL REACTIVITY OF HUMAN PERIPHERAL LEUCOCYTE CHROMOSOMES INDUCED BY LOW TEMPERATURE

1970 • 10 citations

Performance of a Bacterial RNA Polymerase Factor in an Amphibian Oocyte

1970 • 10 citations

Asynchronous DNA Synthesis in a Duplicated Chromosomal Region of Drosophila melanogaster

1971 • 10 citations

The results of electron microscopy on somatic chromosomes of man

1970 • 10 citations

Differential DNA synthesis in heterochromatic and euchromatic chromosome sets of Planococcus citri

1970 • 10 citations

Conformations of nucleohistones and histones

1969 • 9 citations

The distribution of deoxyribonucleic acid-like ribonucleic acid in rat liver cells

1969 • 9 citations

Amino acid incorporation system of the nuclear residual acidic proteins

1967 • 9 citations

Evidence that heavy shoulder DNA may be localized to the microchromosomes of birds

1972 • 9 citations

Effects of RNA and acidic protein on the interaction between DNA and histones

1967 • 8 citations

Zur Ultrastruktur der Chromosomen des Menschen

1969 • 8 citations

Metabolism of high molecular weight, polydisperse, rapidly labeled nuclear RNA in rat liver

1968 • 8 citations

Preparations for Electron Microscopy of Residual Chromosomes

1951 • 7 citations

Effect of puromycin and cortisol pretreatment on the uptake of [14C]leucine into the globulins, whole histones and residual protein of the rat-liver nucleus

1969 • 7 citations

Nuclear Proteins of Hepatocyte and Erythrocyte Nuclei of Frog Liver

1969 • 7 citations

DNA of rat hepatomas: Search for gene amplification

1971 • 6 citations

In situ analysis of cultured Potorous cells

2009 • 6 citations

COLCHICINE-INDUCED SUPERCONTRACTION OF CHROMOSOMES AND HETEROCHROMATIC SEGMENTS IN <i>VICIA FABA</i>

1968 • 6 citations

Electron Microscopy of Isolated Chromosomes

1952 • 6 citations

Effects of cycloheximide on X-ray induction of chromatid exchanges in synchronous Chinese hamster cells

1971 • 6 citations

Electron Microscopy of Chromosomes in Smears

1952 • 4 citations

Model building studies on the structure of deoxyribonucleohistone

1970 • 4 citations

Replication of chromosomal fibres from isolated metaphase chromosomes

1971 • 4 citations

The use of polyethylenesulphonate in the fractionation of proteins and some aspects of its application to the separation of chromatin proteins

1969 • 2 citations

Heavy shoulder DNA

1972 • 2 citations

Electron Autoradiography of Adenovlrus Infected Cells

1970 • 1 citations

Harden Conference Scans Cell Nucleus

1971 • 1 citations

Studies on the role of histones in the structure and function of chromatin

1970 • 1 citations

a Study of the Structure of Nucleohistone and DNA.

1968 • 1 citations

Some observations on chromatin fibers of isolated pea nuclei

1968 • 1 citations

How Free is DNA ?

1971 • 1 citations

Deleted Work

1955 • 0 citations