Effect of polyethylene glycol-superoxide dismutase and catalase on endotoxemia in pigs

Biology of disease: free radicals and tissue injury.

1982 • 3,078 citations

Biological Defense Mechanisms. THE PRODUCTION BY LEUKOCYTES OF SUPEROXIDE, A POTENTIAL BACTERICIDAL AGENT

1973 • 2,955 citations

The Reduction of Cytochrome c by Milk Xanthine Oxidase

1968 • 1,201 citations

Role of hydrogen peroxide in neutrophil-mediated destruction of cultured endothelial cells.

1981 • 587 citations

Free Radicals as Mediators of Tissue Injury

1991 • 386 citations

Effect of N-acetylcysteine on the pulmonary response to endotoxin in the awake sheep and upon in vitro granulocyte function.

1984 • 310 citations

Pulmonary capillary pressure and filtration coefficient in the isolated perfused lung

1967 • 305 citations

Granulocytes mediate acute edematous lung injury in rabbits and in isolated rabbit lungs perfused with phorbol myristate acetate: role of oxygen radicals.

1982 • 257 citations

The Risk Factors, Incidence, and Prognosis of ARDS following Septicemia

1983 • 254 citations

Acute effects of Escherichia coli endotoxin on the pulmonary microcirculation of anesthetized sheep structure:function relationships.

1983 • 245 citations

Systemic complement activation, lung injury, and products of lipid peroxidation.

1985 • 237 citations

Oxygen-radical-mediated permeability edema and vasoconstriction in isolated perfused rabbit lungs.

1982 • 222 citations

Neutrophils Kill Pulmonary Endothelial Cells by a Hydrogen-Peroxide-Dependent Pathway

1984 • 213 citations

Intact human erythrocytes prevent hydrogen peroxide-mediated damage to isolated perfused rat lungs and cultured bovine pulmonary artery endothelial cells.

1984 • 132 citations

Superoxide dismutase with heparin prevents increased lung vascular permeability during air emboli in sheep

1983 • 82 citations

A suggested role for hydrogen peroxide in the biosynthesis of prostaglandins

1974 • 72 citations

Barbiturates as protective agents in brain ischemia and as free radical scavengers in vitro.

1980 • 69 citations

Endotoxemia causes increased lung tissue lipid peroxidation in unanesthetized sheep

1986 • 68 citations

Dexamethasone and indomethacin modify endotoxin-induced respiratory failure in pigs

1985 • 67 citations

Effects of vascular pressure on the pulmonary microvasculature in isolated dog lungs

1984 • 58 citations

Safety evaluation of free radical scavengers peg-catalase and peg-superoxide dismutase

1986 • 48 citations

Endotoxemia-induced leukopenia in sheep. Correlation with lung vascular permeability and hypoxemia but not with pulmonary hypertension.

1983 • 42 citations

Potentiation of lung vascular response to endotoxin by superoxide dismutase

1985 • 39 citations

Complement and neutrophil-mediated injury of perfused rat lungs.

1986 • 37 citations

Prostaglandin and thromboxane levels during endotoxin-induced respiratory failure in pigs

1987 • 21 citations

Prevention of Free Radical Mediated Vascular Permeability Increases in Lung Using Superoxide Dismutase

1983 • 20 citations