Bacteroides fragilis toxin rapidly intoxicates human intestinal epithelial cells (HT29/C1) in vitro

Human Fecal Flora: The Normal Flora of 20 Japanese-Hawaiians

1974 • 1,066 citations

Regulated internalization of caveolae.

1994 • 760 citations

Potocytosis: Sequestration and Transport of Small Molecules by Caveolae

1992 • 751 citations

The Enterotoxin from Clostridium difficile (ToxA) Monoglucosylates the Rho Proteins

1995 • 478 citations

Non-coated membrane invaginations are involved in binding and internalization of cholera and tetanus toxins

1982 • 428 citations

Diarrhea in Developed and Developing Countries: Magnitude, Special Settings, and Etiologies

1990 • 426 citations

Clostridium difficile toxin A perturbs cytoskeletal structure and tight junction permeability of cultured human intestinal epithelial monolayers.

1988 • 398 citations

Shared Actions of Endotoxin and Taxol on TNF Receptors and TNF release

1990 • 288 citations

Accessory cholera enterotoxin (Ace), the third toxin of a Vibrio cholerae virulence cassette.

1993 • 275 citations

Enteropathogens Associated with Acute Diarrheal Disease in Urban Infants in Sao Paulo, Brazil

1991 • 263 citations

Ligands internalized through coated or noncoated invaginations follow a common intracellular pathway.

1987 • 254 citations

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1989 • 240 citations

Anaerobic Bacteria of the Gastrointestinal Flora and Their Occurrence in Clinical Infections

1969 • 230 citations

Inhibitors of receptor-mediated endocytosis block the entry of Bacillus anthracis adenylate cyclase toxin but not that of Bordetella pertussis adenylate cyclase toxin

1988 • 210 citations

Clostridium difficile toxin B disrupts the barrier function of T84 monolayers

1992 • 194 citations

Bacteroides fragilis Subspecies in Clinical Isolates

1977 • 188 citations

Nocodazole, a microtubule-active drug, interferes with apical protein delivery in cultured intestinal epithelial cells (Caco-2).

1989 • 176 citations

The enterotoxin of Bacteroides fragilis is a metalloprotease

1995 • 174 citations

Effects of Clostridium difficile toxins A and B in rabbit small and large intestine in vivo and on cultured cells in vitro

1988 • 159 citations

Bacteroides fragilis: a possible cause of acute diarrheal disease in newborn lambs

1984 • 155 citations

Mechanism of cholera toxin action on a polarized human intestinal epithelial cell line: role of vesicular traffic

1992 • 150 citations

Brefeldin A blocks the response of cultured cells to cholera toxin. Implications for intracellular trafficking in toxin action

1993 • 126 citations

Isolation of enterotoxigenic Bacteroides fragilis from Bangladeshi children with diarrhea: a controlled study

1994 • 119 citations

Human colonic epithelial cells, HT29/C1, treated with crude Bacteroides fragilis enterotoxin dramatically alter their morphology

1992 • 115 citations

Mechanism of action of Escherichia coli heat stable enterotoxin in a human colonic cell line.

1988 • 115 citations

Effects of brefeldin A on endocytosis, transcytosis and transport to the Golgi complex in polarized MDCK cells.

1992 • 105 citations

Properties of ion channels formed by Staphylococcus aureus δ-toxin

1988 • 105 citations

Enterotoxigenic Bacteroides fragilis: epidemiologic studies of its role as a human diarrhoeal pathogen.

1992 • 101 citations

Entry of cholera toxin into polarized human intestinal epithelial cells. Identification of an early brefeldin A sensitive event required for A1-peptide generation.

1993 • 98 citations

Purification and characterization of an enterotoxin from Bacteroides fragilis

1992 • 95 citations

Proteolytic activity of the Bacteroides fragilis enterotoxin causes fluid secretion and intestinal damage in vivo

1995 • 95 citations

Cloning and characterization of the Bacteroides fragilis metalloprotease toxin gene

1997 • 88 citations

Internalization of Clostridium difficile cytotoxin into cultured human lung fibroblasts

1983 • 88 citations

Calcium influx mediated by the Escherichia coli heat-stable enterotoxin B (STB).

1993 • 84 citations

Cellular internalisation of Clostridium difficile toxin A

1987 • 83 citations

Association of Bacteroides fragilis with Childhood Diarrhea

1995 • 79 citations

Enterotoxigenic Bacteroides fragilis

1995 • 79 citations

Human intestinal epithelial cells swell and demonstrate actin rearrangement in response to the metalloprotease toxin of Bacteroides fragilis

1996 • 69 citations

Clostridium perfringens enterotoxin acts by producing small molecule permeability alterations in plasma membranes

1994 • 68 citations

Studies of Clostridium perfringens enterotoxin action at different temperatures demonstrate a correlation between complex formation and cytotoxicity

1990 • 65 citations

Detection of Toxin Production by Bacteroides fragilis: Assay Development and Screening of Extraintestinal Clinical Isolates

1996 • 55 citations

Bacteroides fragilis enterotoxin induces cytoskeletal changes and surface blebbing in HT-29 cells

1996 • 50 citations

The structure ofEscherichia coliheat-stable enterotoxin b by nuclear magnetic resonance and circular dichroism

1995 • 46 citations

Inhibition of heat-labile cholera and Escherichia coli enterotoxins by brefeldin A

1993 • 41 citations

A recombinant C‐terminal toxin fragment provides evidence that membrane insertion is important for Clostridium perfringens enterotoxin cytotoxicity

1991 • 34 citations

Signal transduction by cholera toxin: processing in vesicular compartments does not require acidification

1995 • 33 citations

Biological mode of action of Clostridium difficile toxin A: a novel enterotoxin

1987 • 27 citations

Characterization of enterotoxigenic Bacteroides fragilis by a toxin-specific enzyme-linked immunosorbent assay

1994 • 23 citations

Primary amines and chloroquine inhibit cytotoxic responses to Shigella toxin and permit late antibody rescue of toxin treated cells

1984 • 17 citations

Isolation of Enterotoxigenic Bacteroides fragilis from Extraintestinal Sites by Cell Culture Assay

1995 • 17 citations

A bioassay for cholera-like toxins using HT29 cells

1991 • 7 citations