Human T-cell leukemia virus type II Rex binding and activity require an intact splice donor site and a specific RNA secondary structure

Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma

1980 • 5,022 citations

A catalogue of splice junction sequences

1982 • 3,861 citations

Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information

1981 • 3,596 citations

ANTIBODIES TO HUMAN T-LYMPHOTROPIC VIRUS TYPE-I IN PATIENTS WITH TROPICAL SPASTIC PARAPARESIS

1985 • 2,840 citations

Adult T-cell leukemia: antigen in an ATL cell line and detection of antibodies to the antigen in human sera.

1981 • 2,281 citations

Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease.

1982 • 2,170 citations

A New Subtype of Human T-Cell Leukemia Virus (HTLV-II) Associated with a T-Cell Variant of Hairy Cell Leukemia

1982 • 1,195 citations

Monoclonal integration of human T-cell leukemia provirus in all primary tumors of adult T-cell leukemia suggests causative role of human T-cell leukemia virus in the disease.

1984 • 886 citations

Trans -Acting Transcriptional Activation of the Long Terminal Repeat of Human T Lymphotropic Viruses in Infected Cells

1984 • 781 citations

Inhibition of restriction endonuclease Nel I cleavage by phosphorothioate groups and its application to oligonucleotide-directed mutagenesis

1986 • 560 citations

The pX Protein of HTLV-I Is a Transcriptional Activator of Its Long Terminal Repeats

1985 • 514 citations

High Rate of HTLV-II Infection in Seropositive IV Drug Abusers in New Orleans

1989 • 426 citations

Prevalence of Antibodies to HTLV-I, -II, and -III in Intravenous Drug Abusers From an AIDS Endemic Region

1986 • 340 citations

Functional activation of the long terminal repeat of human T-cell leukemia virus type I by a trans-acting factor.

1985 • 283 citations

A Second Isolate of HTLV-II Associated with Atypical Hairy-Cell Leukemia

1986 • 282 citations

Detection of Human T-Cell Lymphoma/Leukemia Virus Type I DNA and Antigen in Spinal Fluid and Blood of Patients with Chronic Progressive Myelopathy

1988 • 279 citations

Post-transcriptional regulator (rex) of HTLV-1 initiates expression of viral structural proteins but suppresses expression of regulatory proteins.

1988 • 273 citations

Transcriptional (p40x) and post-transcriptional (p27x-III) regulators are required for the expression and replication of human T-cell leukemia virus type I genes.

1987 • 245 citations

Identification of the gene responsible for human T-cell leukaemia virus transcriptional regulation

1985 • 215 citations

A survey of human leukaemias for sequences of a human retrovirus

1983 • 195 citations

Comparative analysis of the HTLV-I Rex and HIV-1 Rev trans-regulatory proteins and their RNA response elements.

1989 • 188 citations

Structure of 3′ Terminal Region of Type II Human T Lymphotropic Virus: Evidence for New Coding Region

1984 • 166 citations

The x Gene Is Essential for HTLV Replication

1985 • 161 citations

LOW PREVALENCE IN THE UK OF HTLV-I AND HTLV-II INFECTION IN SUBJECTS WITH AIDS, WITH EXTENDED LYMPHADENOPATHY, AND AT RISK OF AIDS

1984 • 125 citations

Structure-function analyses of the HTLV-I Rex and HIV-1 Rev RNA response elements: insights into the mechanism of Rex and Rev action.

1990 • 119 citations

Identification of two distinct elements in the long terminal repeat of HTLV-I responsible for maximum gene expression.

1987 • 91 citations

Long terminal repeats of human T-cell leukaemia virus II genome determine target cell specificity

1984 • 84 citations

The type I human T-cell leukemia virus (HTLV-I) Rex trans-activator binds directly to the HTLV-I Rex and the type 1 human immunodeficiency virus Rev RNA response elements.

1991 • 83 citations

Secondary structure of the human T-cell leukemia virus type 1 rex-responsive element is essential for rex regulation of RNA processing and transport of unspliced RNAs

1990 • 79 citations

Functional analysis of human T-cell leukemia virus type I rex-response element: direct RNA binding of Rex protein correlates with in vivo activity

1991 • 76 citations

Expression of the 3′ Terminal Region of Human T-Cell Leukemia Viruses

1984 • 73 citations

Repetitive structure in the long-terminal-repeat element of a type II human T-cell leukemia virus.

1984 • 71 citations

HTLV-II Transactivation Is Regulated by the Overlapping tax / rex Nonstructural Genes

1988 • 68 citations

In vitro binding of human T-cell leukemia virus rex proteins to the rex-response element of viral transcripts

1991 • 64 citations

Identification of a cis-regulatory element involved in accumulation of human T-cell leukemia virus type II genomic mRNA

1988 • 49 citations

Regulation of HTLV-II gene expression by rex involves positive and negative cis-acting elements in the 5′ long terminal repeat

1991 • 38 citations

Rex transregulation of human T-cell leukemia virus type II gene expression

1991 • 35 citations

Human T-cell leukemia virus (HTLV) type II Rex protein binds specifically to RNA sequences of the HTLV long terminal repeat but poorly to the human immunodeficiency virus type 1 Rev-responsive element

1991 • 28 citations