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Identification of point mutations in the envelope gene of Moloney murine leukemia virus TB temperature-sensitive paralytogenic mutant ts1: molecular determinants for neurovirulence

Data up to Jan 2025

Published1988
Citations88
References26

Total Citations Per Year

Abstract

References (26)

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The neurovirulent determinants of ts1, a paralytogenic mutant of Moloney murine leukemia virus TB, are localized in at least two functionally distinct regions of the genome

1986 • 45 citations

A 1.6-kilobase-pair fragment in the genome of the ts1 mutant of Moloney murine leukemia virus TB that is associated with temperature sensitivity, nonprocessing of Pr80env, and paralytogenesis

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ts1, a Paralytogenic mutant of Moloney murine leukemia virus TB, has an enhanced ability to replicate in the central nervous system and primary nerve cell culture

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Identification of point mutations in the envelope gene of Moloney murine leukemia virus… (1988) – Journal of Virology | Metascience Observatory Explorer