Pharmacokinetics of vitamin D toxicity

Vitamin D Deficiency

2007 • 12,815 citations

Principles of Bone Biology

2019 • 1,699 citations

The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed

1998 • 1,391 citations

Current Understanding of the Molecular Actions of Vitamin D

1998 • 1,259 citations

Enzymes involved in the activation and inactivation of vitamin D

2004 • 633 citations

Assessment of the Free Fraction of 25-Hydroxyvitamin D in Serum and Its Regulation by Albumin and the Vitamin D-Binding Protein *

1986 • 593 citations

Principles of Bone Biology

2008 • 327 citations

Hypervitaminosis D Associated with Drinking Milk

1992 • 285 citations

Isolation and Structural Identification of 1,25- Dihydroxyvitamin D₃Produced by Cultured Alveolar Macrophages in Sarcoidosis*

1985 • 272 citations

Human plasma transport of vitamin D after its endogenous synthesis.

1993 • 263 citations

25-Hydroxyvitamin D transport in human plasma. Isolation and partial characterization of calcifidiol-binding protein.

1976 • 218 citations

Altered Pharmacokinetics of 1α,25-Dihydroxyvitamin D₃and 25-Hydroxyvitamin D₃in the Blood and Tissues of the 25-Hydroxyvitamin D-24-Hydroxylase (Cyp24a1) Null Mouse

2004 • 175 citations

The mechanisms of vitamin D toxicity

1990 • 171 citations

PHOSPHORUS METABOLISM AND MANAGEMENT IN CHRONIC KIDNEY DISEASE: Expanding Role for Vitamin D in Chronic Kidney Disease: Importance of Blood 25‐OH‐D Levels and Extra‐Renal 1α‐Hydroxylase in the Classical and Nonclassical Actions of 1α,25‐Dihydroxyvitamin D₃

2007 • 158 citations

Serum Levels of Free 1,25-Dihydroxyvitamin D in Vitamin D Toxicity

1995 • 153 citations

The Metabolism of Isotopically Labelled Vitamin D3 in Man: The Influence of the State of Vitamin D Nutrition

1971 • 153 citations

The Effects of Chloroquine on Serum 1,25-Dihydroxyvitamin D and Calcium Metabolism in Sarcoidosis

1986 • 149 citations

Plasma concentrations of vitamin D3 and its metabolites in the rat as influenced by vitamin D3 or 25-hydroxyvitamin D3 intakes

1980 • 148 citations

Free, and Not Total, 1,25-Dihydroxyvitamin D Regulates 25-Hydroxyvitamin D Metabolism by Keratinocytes

1989 • 138 citations

Isolation and characterization of 1.alpha.-hydroxy-23-carboxytetranorvitamin D: a major metabolite of 1,25-dihydroxyvitamin D3

1979 • 129 citations

Vitamin D intoxication causes hypercalcaemia by increased bone resorption which responds to pamidronate

1995 • 117 citations

An outbreak of hypervitaminosis D associated with the overfortification of milk from a home-delivery dairy.

1995 • 114 citations

Vitamin D analogues for secondary hyperparathyroidism

2002 • 103 citations

Acute Vitamin D Intoxication in a Child

2005 • 100 citations

A Phase I Pharmacokinetic and Pharmacodynamic Study of Intravenous Calcitriol in Combination with Oral Gefitinib in Patients with Advanced Solid Tumors

2007 • 90 citations

Vitamin D3Toxicity in Dairy Cows,

1982 • 87 citations

Hypercalcemia and hyperosteolysis in vitamin D intoxication: Effects of clodronate therapy

1994 • 84 citations

Correlation between 25-hydroxyvitamin D3 1α-hydroxylase gene expression in alveolar macrophages and the activity of sarcoidosis

2001 • 77 citations

Quantitative studies of the interaction of cholecalciferol (vitamin D3) and its metabolites with different genetic variants of the serum binding protein for these sterols

1979 • 73 citations

Side-chain hydroxylation of vitamin D3 and its physiological implications

1987 • 70 citations

Vitamin D Intoxication in an Anephric Child

1975 • 64 citations

Single A326G mutation converts human CYP24A1 from 25-OH-D ₃ -24-hydroxylase into -23-hydroxylase, generating 1α,25-(OH) ₂ D ₃ -26,23-lactone

2007 • 60 citations

Contemporary Diagnosis and Treatment of Vitamin D–Related Disorders

2007 • 45 citations

Research-articleVitamin D3Toxicity in Dairy Cows1,2

1982 • 45 citations

Pharmacokinetics and biologic effects of calcitriol in normal humans.

1985 • 41 citations

Metabolism of Vitamin D₃in Nephrectomized Pigs Given Pharmacological Amounts of Vitamin D₃

1982 • 39 citations

Activation of the human osteocalcin gene by 24r,25-dihydroxyvitamin d3 occurs through the vitamin d receptor and the vitamin d-responsive element

1994 • 38 citations

Effects of pharmacological doses of Vitamin D3 on mineral balance and profiles of plasma Vitamin D3 metabolites in horses

2004 • 37 citations

24-Hydroxylase: potential key regulator in hypervitaminosis D₃in growing dogs

2003 • 32 citations

Hepatic activation and inactivation of clinically-relevant vitamin D analogs and prodrugs.

2006 • 31 citations

A family with massive acute vitamin D intoxication

1979 • 24 citations

Unusual cases of chronic intoxication by vitamin D.

2004 • 23 citations

Nephrocalcinosis due to vitamin D intoxication.

1989 • 13 citations

Vitamin D and Analogues

2008 • 11 citations

25-Hydroxy-vitamin D levels in a patient with hypervitaminosis D

1978 • 10 citations

[Circulating metabolites of vitamin D in 14 children with hypercalcemia].

1985 • 8 citations