Sepiapterin Reductase and ALR2 (“Aldose Reductase”) from Bovine Brain

A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples

1978 • 6,494 citations

Chemistry and biology of pteridines

1956 • 1,263 citations

BIOSYNTHESIS AND METABOLISM OF TETRAHYDROBIOPTERIN AND MOLYBDOPTERIN

1985 • 542 citations

An Unlikely Sugar Substrate Site in the 1.65 Å Structure of the Human Aldose Reductase Holoenzyme Implicated in Diabetic Complications

1992 • 431 citations

Brain nitric oxide synthase is a biopterin‐ and flavin‐containing multi‐functional oxido‐reductase

1991 • 422 citations

THE STRUCTURE OF THE PHENYLALANINE-HYDROXYLATION COFACTOR

1963 • 378 citations

Purification and properties of an NADPH-dependent carbonyl reductase from human brain. Relationship to prostaglandin 9-ketoreductase and xenobiotic ketone reductase.

1981 • 314 citations

Novel NADPH-binding domain revealed by the crystal structure of aldose reductase

1992 • 193 citations

Purification and properties of a 3α-hydroxysteroid dehydrogenase of rat liver cytosol and its inhibition by anti-inflammatory drugs

1984 • 187 citations

Mammalian Carbonyl Reductases

1980 • 173 citations

Structural similarity of bovine lung prostaglandin F synthase to lens epsilon-crystallin of the European common frog.

1988 • 156 citations

Enzymatic formation of prostaglandin F2 alpha from prostaglandin H2 and D2. Purification and properties of prostaglandin F synthetase from bovine lung.

1985 • 150 citations

Cloning and sequencing of the cDNA for rat liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase

1991 • 148 citations

Human carbonyl reductase. Nucleotide sequence analysis of a cDNA and amino acid sequence of the encoded protein.

1988 • 131 citations

Aldehyde reductases: Monomeric NAPDH-dependent oxidoreductases with multifunctional potential

1982 • 122 citations

Human Brain Aldehyde Reductases: Relationship to Succinic Semialdehyde Reductase and Aldose Reductase

1980 • 93 citations

Isolation and characterization of cloned cDNAs encoding human liver chlordecone reductase

1990 • 92 citations

PURIFICATION FROM HUMAN BRAIN AND SOME PROPERTIES OF TWO NADPH‐LINKED ALDEHYDE REDUCTASES WHICH REDUCE SUCCINIC SEMIALDEHYDE TO 4‐HYDROXYBUTYRATE

1979 • 88 citations

Androgen-dependent protein from mouse vas deferens. cDNA cloning and protein homology with the aldo-keto reductase superfamily.

1990 • 84 citations

Purification and Properties of an NADPH-dependent Carbonyl Reductase from Human Brain

1980 • 83 citations

A superfamily of NADPH-dependent reductases in eukaryotes and prokaryotes

1989 • 78 citations

Human carbonyl and aldose reductases: New catalytic functions in tetrahydrobiopterin biosynthesis

1991 • 74 citations

The kinetic mechanism catalysed by homogeneous rat liver 3α-hydroxysteroid dehydrogenase. Evidence for binary and ternary dead-end complexes containing non-steroidal anti-inflammatory drugs

1991 • 73 citations

Direct inhibition of brain sepiapterin reductase by a catecholamine and an indoleamine

1982 • 68 citations

Purification and characterization of sepiapterin reductase from rat erythrocytes

1982 • 67 citations

Sepiapterin reductase from horse liver: Purification and properties of the Enzyme

1971 • 66 citations

Purification and properties of prostaglandin 9‐ketoreductase from pig and human kidney

1992 • 64 citations

Stereospecificity of Hydrogen Transfer by Pyridine Nucleotide-linked Hydroxysteroid Dehydrogenases

1960 • 60 citations

Enzymatic Conversion of a Δ⁴‐3‐Ketosteroid into a 3α‐Hydroxy‐5β‐Steroid: Mechanism and Stereochemistry of Hydrogen Transfer from NADPH

1967 • 59 citations

Cloning and sequencing of cDNA encoding human sepiapterin reductase

1991 • 57 citations

Sepiapterin reductase

1966 • 57 citations

Specific and non‐specific succinic semialdehyde reductases from rat brain: Isolation and properties

1980 • 57 citations

Purification and Some Properties of Aldehyde Rcductases from Pig Liver

1980 • 55 citations

The biosynthesis of tetrahydrobiopterin in rat brain

1989 • 55 citations

Tetrahydrobiopterin biosynthesis. Studies with specifically labeled (2H)NAD(P)H and 2H2O and of the enzymes involved

1985 • 50 citations

Synthesis, utilization, and structure of the tetrahydropterin intermediates in the bovine adrenal medullary de novo biosynthesis of tetrahydrobiopterin.

1986 • 48 citations

Immunological Evidence for the Requirement of Sepiapterin Reductase for Tetrahydrobiopterin Biosynthesis in Brain

1990 • 47 citations

Substrate specificity of three prostaglandin dehydrogenases

1983 • 46 citations

Studies on sepiapterin reductase: Further characterization of the reaction product

1968 • 46 citations

Purification and characterization of rho-crystallin from Japanese common bullfrog lens.

1990 • 45 citations

Sepiapterin reductase exhibits a NADPH-dependent dicarbonyl reductase activity

1984 • 45 citations

Carbonyl reductase activity of sepiapterin reductase from rat erythrocytes

1985 • 42 citations

Purification and characterization of chlordecone reductase from human liver.

1986 • 42 citations

On the role of sepiapterin reductase in the biosynthesis of tetrahydrobiopterin

1987 • 41 citations

New inhibitors of sepiapterin reductase. Lack of an effect of intracellular tetrahydrobiopterin depletion upon in vitro proliferation of two human cell lines.

1992 • 40 citations

Inhibition of hexonate dehydrogenase and aldose reductase from bovine retina by Sorbinil, Statil, M79175 and valproate

1986 • 39 citations

Immunological studies on the participation of 6-pyruvoyl tetrahydropterin (2′-oxo) reductase, an aldose reductase, in tetrahydrobiopterin biosynthesis

1989 • 38 citations

Characterization of pulmonary carbonyl reductase of mouse and guinea pig

1986 • 37 citations

Purification and characterization of a novel pyrazole-sensitive carbonyl reductase in guinea pig lung

1982 • 36 citations

Occurrence of Two Different Enzymes in the Silkworm, Bombyx mori, to reduce Folate and Sepiapterin

1963 • 33 citations

Stereospecificity of the hydrogen transfer catalyzed by human placental aldose reductase

1977 • 32 citations

Unconjugated pterins and related biogenic amines

1989 • 30 citations

Human liver 6-pyruvoyl tetrahydropterin reductase is biochemically and immunologically indistinguishable from aldose reductase

1989 • 26 citations

Stereochemistry of reduction of D-glyceraldehyde catalyzed by a nicotinamide adenine dinucleotide phosphate dependent dehydrogenase from skeletal muscle

1973 • 25 citations

Kinetic mechanism of sheep liver NADPH-dependent aldehyde reductase

1987 • 24 citations

A mitochondrial NADP+-dependent reductase related to the 4-aminobutyrate shunt. Purification, characterization, and mechanism.

1985 • 22 citations

The complete amino acid sequence of the mature form of rat sepiapterin reductase

1990 • 19 citations

Stereospecificity of hydrogen transfer of aldehyde reductase

1979 • 19 citations

Purification and Characterization of Four NADPH‐Dependent Aldehyde Reductases from Pig Brain

1985 • 17 citations

On the presence of sepiapterin reductase different from folate and dihydrofolate reductase in chicken liver

1964 • 17 citations

Kinetic studies with the low-Km aldehyde reductase from ox brain

1985 • 13 citations

Purification and properties of low-Km aldehyde reductase from ox brain

1984 • 5 citations

Properties of carbonyl reductase activity of sepiapterin reductase, an enzyme involved in the biosynthesis of tetrahydrobiopterin.

1989 • 4 citations