The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma
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References (39)
Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses
2008 • 3,870 citations
Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer
2009 • 2,945 citations
DPC4 , A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1
1996 • 2,320 citations
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
2003 • 2,309 citations
Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes
1988 • 2,121 citations
Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
2003 • 1,967 citations
Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras
2001 • 1,824 citations
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
2011 • 1,218 citations
Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma
1994 • 1,142 citations
DPC4 Gene Status of the Primary Carcinoma Correlates With Patterns of Failure in Patients With Pancreatic Cancer
2009 • 1,011 citations
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization
2002 • 982 citations
Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival
2009 • 585 citations
The HECT Family of E3 Ubiquitin Ligases: Multiple Players in Cancer Development
2008 • 514 citations
Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system
2005 • 485 citations
FAM/USP9x, a Deubiquitinating Enzyme Essential for TGFβ Signaling, Controls Smad4 Monoubiquitination
2009 • 466 citations
p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions.
1994 • 452 citations
Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse
2005 • 404 citations
A Transposon-Based Genetic Screen in Mice Identifies Genes Altered in Colorectal Cancer
2009 • 340 citations
Global survey of escape from X inactivation by RNA-sequencing in mouse
2010 • 333 citations
Immortal Human Pancreatic Duct Epithelial Cell Lines with Near Normal Genotype and Phenotype
2000 • 314 citations
Long-term culture and immortalization of epithelial cells from normal adult human pancreatic ducts transfected by the E6E7 gene of human papilloma virus 16.
1996 • 291 citations
Gene Expression Profiling of Microdissected Pancreatic Ductal Carcinomas Using High-Density DNA Microarrays
2004 • 200 citations
A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma
2009 • 200 citations
Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis
2011 • 186 citations
A high-throughput splinkerette-PCR method for the isolation and sequencing of retroviral insertion sites
2009 • 160 citations
ACVR1B ( ALK4 , activin receptor type 1B) gene mutations in pancreatic carcinoma
2001 • 141 citations
Ubiquitin-like Sequence in ASK1 Plays Critical Roles in the Recognition and Stabilization by USP9X and Oxidative Stress-Induced Cell Death
2009 • 134 citations
LKB1 Somatic Mutations in Sporadic Tumors
1999 • 128 citations
Detecting Statistically Significant Common Insertion Sites in Retroviral Insertional Mutagenesis Screens
2006 • 119 citations
The Ubiquitin Ligase Itch Is Auto-ubiquitylated in Vivo and in Vitro but Is Protected from Degradation by Interacting with the Deubiquitylating Enzyme FAM/USP9X
2006 • 116 citations
Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis
2011 • 115 citations
Activation of Wnt signalling in stroma from pancreatic cancer identified by gene expression profiling
2008 • 98 citations
The Ubiquitin E3 Ligase MARCH7 is Differentially Regulated by the Deubiquitylating Enzymes USP7 and USP9X
2008 • 86 citations
The FAM Deubiquitylating Enzyme Localizes to Multiple Points of Protein Trafficking in Epithelia, where It Associates with E-cadherin and β-catenin
2004 • 81 citations
Efficiency of RNA Interference in the Mouse Hematopoietic System Varies between Cell Types and Developmental Stages
2005 • 77 citations
Whole-Body Sleeping Beauty Mutagenesis Can Cause Penetrant Leukemia/Lymphoma and Rare High-Grade Glioma without Associated Embryonic Lethality
2009 • 70 citations
Electroporation of Murine Embryonic Stem Cells: A Step‐by‐Step Guide
2004 • 59 citations
すい臓癌におけるACVR1B(ALK4、1B型アクチビン受容体)遺伝子の突然変異
2001 • 50 citations
Paternally biased X inactivation in mouse neonatal brain
2010 • 45 citations
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