Allopurinol Attenuates Oxidative Stress and Cardiac Fibrosis in Angiotensin II‐Induced Cardiac Diastolic Dysfunction

Smad-dependent and Smad-independent pathways in TGF-β family signalling

2003 • 5,052 citations

Molecular identification of a danger signal that alerts the immune system to dying cells

2003 • 1,649 citations

New Concepts in Diastolic Dysfunction and Diastolic Heart Failure: Part I

2002 • 1,170 citations

Glutathione deficiency produced by inhibition of its synthesis, and its reversal; Applications in research and therapy

1991 • 906 citations

New Concepts in Diastolic Dysfunction and Diastolic Heart Failure: Part II

2002 • 895 citations

TGF-?1 and angiotensin networking in cardiac remodeling

2004 • 647 citations

Transforming Growth Factor-β Function Blocking Prevents Myocardial Fibrosis and Diastolic Dysfunction in Pressure-Overloaded Rats

2002 • 588 citations

Role of Oxidative Stress in Myocardial Hypertrophy and Failure

2002 • 581 citations

Pivotal Role of a gp91 ^phox -Containing NADPH Oxidase in Angiotensin II-Induced Cardiac Hypertrophy in Mice

2002 • 524 citations

Fibrosis in heart disease: understanding the role of transforming growth factor‐β₁ in cardiomyopathy, valvular disease and arrhythmia

2006 • 479 citations

Role of oxidative stress in transition of hypertrophy to heart failure

1996 • 422 citations

Treatment With Dimethylthiourea Prevents Left Ventricular Remodeling and Failure After Experimental Myocardial Infarction in Mice

2000 • 326 citations

Angiotensin II Has Multiple Profibrotic Effects in Human Cardiac Fibroblasts

2000 • 306 citations

Taurine Supplementation Reduces Oxidative Stress and Improves Cardiovascular Function in an Iron-Overload Murine Model

2004 • 212 citations

Chronic Inhibition of Nitric Oxide Synthesis Causes Coronary Microvascular Remodeling in Rats

1995 • 208 citations

Allopurinol Attenuates Left Ventricular Remodeling and Dysfunction After Experimental Myocardial Infarction

2004 • 205 citations

Role of Osteopontin in Cardiac Fibrosis and Remodeling in Angiotensin II-Induced Cardiac Hypertrophy

2004 • 181 citations

Tumor Necrosis Factor-α Inhibits Transforming Growth Factor-β /Smad Signaling in Human Dermal Fibroblasts via AP-1 Activation

2000 • 172 citations

Decreased Smad 7 expression contributes to cardiac fibrosis in the infarcted rat heart

2002 • 144 citations

Angiotensin II-Dependent Chronic Hypertension and Cardiac Hypertrophy Are Unaffected by gp91phox-Containing NADPH Oxidase

2005 • 134 citations

Evaluation of phospholipid peroxidation as malondialdehyde during myocardial ischemia and reperfusion injury

1991 • 101 citations

Transient reduction in myocardial free oxygen radical levels is involved in the improved cardiac function and structure after long-term allopurinol treatment initiated in established chronic heart failure

2005 • 89 citations

Mice lacking osteopontin exhibit increased left ventricular dilation and reduced fibrosis after aldosterone infusion

2004 • 79 citations

Xanthine oxidase inhibition ameliorates cardiovascular dysfunction in dogs with pacing-induced heart failure

2005 • 71 citations

Xanthine oxidase inhibitors improve energetics and function after infarction in failing mouse hearts

2005 • 67 citations

New insights on myocardial pyridine nucleotides and thiol redox state in ischemia and reperfusion damage

2000 • 59 citations

Xanthine Oxidase Inhibition Improves Left Ventricular Dysfunction in Dilated Cardiomyopathic Hamsters

2008 • 32 citations