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TLR7/8-Mediated Activation of Human NK Cells Results in Accessory Cell-Dependent IFN-γ Production

Data up to Jan 2025

Published2005
Citations296
References50

Total Citations Per Year

Abstract

References (50)

A Toll-like receptor recognizes bacterial DNA

2000 • 6,348 citations

Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

2001 • 5,893 citations

NITRIC OXIDE AND MACROPHAGE FUNCTION

1997 • 4,106 citations

Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8

2004 • 3,766 citations

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

2004 • 3,745 citations

Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA

2004 • 3,325 citations

Toll-like receptors in innate immunity

2004 • 3,233 citations

Small anti-viral compounds activate immune cells via the TLR7 MyD88–dependent signaling pathway

2002 • 2,438 citations

NATURAL KILLER CELLS IN ANTIVIRAL DEFENSE: Function and Regulation by Innate Cytokines

1999 • 2,128 citations

Subsets of Human Dendritic Cell Precursors Express Different Toll-like Receptors and Respond to Different Microbial Antigens

2001 • 1,989 citations

Recognition of single-stranded RNA viruses by Toll-like receptor 7

2004 • 1,777 citations

Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition

2001 • 1,498 citations

Severe Herpesvirus Infections in an Adolescent without Natural Killer Cells

1989 • 1,251 citations

KIR: Diverse, Rapidly Evolving Receptors of Innate and Adaptive Immunity

2002 • 983 citations

Recognition of haemagglutinins on virus-infected cells by NKp46 activates lysis by human NK cells

2001 • 961 citations

Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection

2004 • 946 citations

Toll-like receptor 3 promotes cross-priming to virus-infected cells

2005 • 902 citations

Natural killer cells, viruses and cancer

2001 • 859 citations

Enhanced NK cell activity in mice injected with interferon and interferon inducers

1978 • 735 citations

TLR9-Dependent Recognition of MCMV by IPC and DC Generates Coordinated Cytokine Responses that Activate Antiviral NK Cell Function

2004 • 719 citations

Vital Involvement of a Natural Killer Cell Activation Receptor in Resistance to Viral Infection

2001 • 622 citations

Regulation of Toll-Like Receptors in Human Monocytes and Dendritic Cells

2001 • 604 citations

Unravelling natural killer cell function: triggering and inhibitory human NK receptors

2003 • 602 citations

Viral infection switches non-plasmacytoid dendritic cells into high interferon producers

2003 • 582 citations

Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: Activation of Toll-like receptor 7

2003 • 578 citations

Requirement for natural killer cell-produced interferon gamma in defense against murine cytomegalovirus infection and enhancement of this defense pathway by interleukin 12 administration.

1995 • 458 citations

Establishment of a monoclonal antibody against human Toll-like receptor 3 that blocks double-stranded RNA-mediated signaling

2002 • 449 citations

CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: Induction of cytokine release and cytotoxicity against tumors and dendritic cells

2004 • 443 citations

Activation and function of natural killer cell responses during viral infections

1997 • 430 citations

Recognition of viral hemagglutinins by NKp44 but not by NKp30

2001 • 413 citations

Signal Integration via PKR

2001 • 395 citations

An absolute and restricted requirement for IL-12 in natural killer cell IFN-gamma production and antiviral defense. Studies of natural killer and T cell responses in contrasting viral infections.

1996 • 384 citations

Virus-specific Activation of a Novel Interferon Regulatory Factor, IRF-5, Results in the Induction of Distinct Interferon α Genes

2001 • 374 citations

Leishmania lipophosphoglycan (LPG) activates NK cells through toll-like receptor-2

2003 • 345 citations

Comparative analysis of IRF and IFN-alpha expression in human plasmacytoid and monocyte-derived dendritic cells

2003 • 334 citations

The role of natural killer cells in innate resistance to infection

1993 • 330 citations

Human natural killer cell deficiencies and susceptibility to infection

2002 • 324 citations

Distinct organ-dependent mechanisms for the control of murine cytomegalovirus infection by natural killer cells

1997 • 320 citations

Toll-like Receptors and Their Signaling Mechanisms

2003 • 266 citations

APC-Independent Activation of NK Cells by the Toll-Like Receptor 3 Agonist Double-Stranded RNA

2004 • 236 citations

Ligand-regulated Chimeric Receptor Approach Reveals Distinctive Subcellular Localization and Signaling Properties of the Toll-like Receptors

2004 • 235 citations

Immunobiology of Natural Killer Cells

2019 • 174 citations

The T-cell-independent role of gamma interferon and tumor necrosis factor alpha in macrophage activation during murine cytomegalovirus and herpes simplex virus infections

1995 • 172 citations

Cooperation of Natural Killer Cell Stimulatory Factor/Interleukin-12 with Other Stimuli in the Induction of Cytokines and Cytotoxic Cell-Associated Molecules in Human T and NK Cells

1994 • 162 citations

Late phase inhibition of murine cytomegalovirus replication by synergistic action of interferon-gamma and tumour necrosis factor

1994 • 153 citations

Depletion of NK cells results in disseminating lethal infection with Bordetella pertussis associated with a reduction of antigen‐specific Th1 and enhancement of Th2, but not Tr1 cells

2004 • 134 citations

p38 MAPK activation controls the TLR3-mediated up-regulation of cytotoxicity and cytokine production in human NK cells

2004 • 116 citations

Innate Immune Responses to LCMV Infections: Natural Killer Cells and Cytokines

2002 • 74 citations

Function and Regulation of Natural Killer (NK) Cells during Viral Infections: Characterization of Responsesin Vivo

1996 • 45 citations

Natural Killer Cells Active Against Viral, Bacterial, Protozoan, and Fungal Infections

2019 • 4 citations

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TLR7/8-Mediated Activation of Human NK Cells Results in Accessory Cell-Dependent IFN-γ… (2005) – The Journal of Immunology | Metascience Observatory Explorer