Mutations that affect phosphorylation of the adenovirus DNA-binding protein alter its ability to enhance its own synthesis

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

Rapid Isolation of Antigens from Cells with A Staphylococcal Protein A-Antibody Adsorbent: Parameters of the Interaction of Antibody-Antigen Complexes with Protein A

1975 • 3,054 citations

PROTEIN-TYROSINE KINASES

1985 • 2,198 citations

How eukaryotic transcriptional activators work

1988 • 1,924 citations

GAL4-VP16 is an unusually potent transcriptional activator

1988 • 1,379 citations

The role of protein phosphorylation in neural and hormonal control of cellular activity

1982 • 1,116 citations

Oligonucleotide-Directed Mutagenesis: A Simple Method Using Two Oligonucleotide Primers and a Single-Stranded DNA Template

1984 • 947 citations

Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation

1988 • 886 citations

Transcription activation by the adenovirus E1a protein

1989 • 667 citations

Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src

1987 • 567 citations

Promoters, activator proteins, and the mechanism of transcriptional initiation in yeast

1987 • 476 citations

The phosphorylase b to a converting enzyme of rabbit skeletal muscle

1956 • 463 citations

Adenovirus DNA replication in vitro: identification of a host factor that stimulates synthesis of the preterminal protein-dCMP complex.

1982 • 350 citations

DNA replication and the early to late transition in adenovirus infection

1980 • 248 citations

Simian Virus 40 Large T Antigen Is Phosphorylated at Multiple Sites Clustered in Two Separate Regions

1982 • 193 citations

E1A 13S and 12S mRNA Products Made in Escherichia coli Both Function as Nucleus-Localized Transcription Activators but Do Not Directly Bind DNA

1985 • 190 citations

2B or not 2B: Regulation of the catalytic utilization of elF-2

1983 • 172 citations

Mutations that allow human Ad2 and Ad5 to express late genes in monkey cells map in the viral gene encoding the 72K DNA binding protein

1979 • 170 citations

An adenovirus type 5 gene function required for initiation of viral DNA replication

1975 • 147 citations

Autoregulated changes in stability of polyribosome-bound beta-tubulin mRNAs are specified by the first 13 translated nucleotides.

1988 • 141 citations

The stability of early adenovirus mRNA is controlled by the viral 72 kd DNA-binding protein

1981 • 134 citations

Biological activities of EGF-receptor mutants with individually altered autophosphorylation sites.

1988 • 132 citations

Physical mapping of a large-plaque mutation of adenovirus type 2

1979 • 125 citations

Mutations in the phosphorylation sites of simian virus 40 (SV40) T antigen alter its origin DNA-binding specificity for sites I or II and affect SV40 DNA replication activity

1988 • 125 citations

Possible role of the 72,000 dalton DNA-binding protein in regulation of adenovirus type 5 early gene expression

1978 • 124 citations

Structure-function relationships of the adenovirus DNA-binding protein.

1979 • 118 citations

Block to multiplication of adenovirus serotype 2 in monkey cells

1975 • 111 citations

Isolation of type 5 adenovirus mutants with a cold-sensitive host range phenotype: Genetic evidence of an adenovirus transformation maintenance function

1982 • 103 citations

Phosphoproteins of adenovirus 2

1978 • 93 citations

Characterization of Adenovirus Protein IX

1979 • 87 citations

The isolation and identification of the adenovirus group C tumor antigens

1977 • 84 citations

Identification of two nuclear subclasses of the adenovirus type 5-encoded DNA-binding protein

1986 • 79 citations

Inhibition of adenovirus early region IV transcription in vitro by a purified viral DNA binding protein

1983 • 69 citations

Conditional lethal mutants of adenovirus type 2-simian virus 40 hybrids. II. Ad2+ND1 host-range mutants that synthesize fragments of the Ad2+ND1 30K protein

1976 • 69 citations

Further Characterization of the Phosphate Moiety of the Adenovirus Type 2 DNA‐Binding Protein

1980 • 68 citations

Effects of the adenovirus H5ts125 and H5ts107 DNA binding proteins on DNA replication in Vitro

1983 • 67 citations

Removal of serine phosphates from simian virus 40 large T antigen increases its ability to stimulate DNA replication in vitro but has no effect on ATPase and DNA binding

1987 • 66 citations

A cleavage product of the adenovirus DNA binding protein is active in DNA replication in vitro

1980 • 66 citations

Purification and Characterization of the Phosphorylated DNA-Binding Protein from Adenovirus-Type-2-Infected Cells

1977 • 64 citations

Introduction, stable integration, and controlled expression of a chimeric adenovirus gene whose product is toxic to the recipient human cell.

1984 • 59 citations

Host range temperature-conditional mutants in the adenovirus DNA binding protein are defective in the assembly of infectious virus

1983 • 59 citations

Phosphorylation downregulates the DNA-binding activity of simian virus 40 T antigen

1986 • 58 citations

Altered mRNA splicing in monkey cells abortively infected with human adenovirus may be responsible for inefficient synthesis of the virion fiber polypeptide.

1984 • 57 citations

Effects of in vitro dephosphorylation on DNA-binding and DNA helicase activities of simian virus 40 large tumor antigen

1988 • 56 citations

Isolation of a variant of human adenovirus serotype 2 that multiplies efficiently on monkey cells

1977 • 55 citations

Isolation and analysis of adenovirus type 5 mutants containing deletions in the gene encoding the DNA-binding protein

1985 • 49 citations

Nucleotide sequence of the gene encoding adenovirus type 2 DNA binding protein

1982 • 49 citations

Independent, spontaneous mutants of adenovirus type 2-simian virus 40 hybrid Ad2+ND3 that grow efficiently in monkey cells possess indentical mutations in the adenovirus type 2 DNA-binding protein gene

1983 • 46 citations

Sequence of the dna-binding protein of a human subgroup E adenovirus (type 4): Comparisons with subgroup A (type 12), subgroup B (type 7), and subgroup C (type 5)

1985 • 45 citations

Binding of dephosphorylated a protein to SV40 DNA

1981 • 45 citations

Immunofluorescence Study of the Adenovirus Type 2 Single-Stranded DNA Binding Protein in Infected and Transformed Cells

1977 • 44 citations

Partial block to transcription of human adenovirus type 2 late genes in abortively infected monkey cells

1985 • 41 citations

The genes encoding the DNA binding protein and the 23K protease of adenovirus types 40 and 41

1988 • 40 citations

Enhanced infectivity of adenovirus type 2 DNA and a DNA-protein complex

1978 • 40 citations

Posttranscriptional block to synthesis of a human adenovirus capsid protein in abortively infected monkey cells.

1983 • 40 citations

Autoregulated Changes in Stability of Polyribosome-Bound β-Tubulin mRNAs Are Specified by the First 13 Translated Nucleotides

1988 • 40 citations

Heterogeneity of adenovirus type 5 E1A proteins: multiple serine phosphorylations induce slow-migrating electrophoretic variants but do not affect E1A-induced transcriptional activation or transformation

1988 • 40 citations

Genetic mapping of a major site of phosphorylation in adenovirus type 2 E1A proteins

1986 • 40 citations

Association of the adenovirus DNA-binding protein with RNA both in vitro and in vivo.

1986 • 39 citations

Interaction between adenovirus DNA-binding protein and single-stranded polynucleotides studied by circular dichroism and ultraviolet absorption

1987 • 37 citations

Restricted changes in the adenovirus DNA-binding protein that lead to extended host range or temperature-sensitive phenotypes

1985 • 33 citations

Introduction, Stable Integration, and Controlled Expression of a Chimeric Adenovirus Gene Whose Product Is Toxic to the Recipient Human Cell

1984 • 29 citations

Isolation and characterization of a viable adenovirus mutant defective in nuclear transport of the DNA-binding protein

1989 • 27 citations

Synthesis of human adenovirus early RNA species is similar in productive and abortive infections of monkey and human cells

1982 • 25 citations

Phosphorylation at serine 89 induces a shift in gel mobility but has little effect on the function of adenovirus type 5 E1A proteins

1989 • 22 citations

DNA-binding properties of phosphorylated and dephosphorylated D2-T antigen, a simian-virus-40 T-antigen-related protein

2008 • 20 citations

Characterization of adenovirus type 5 insertion and deletion mutants encoding altered DNA binding proteins

1989 • 11 citations

Mapping of a phosphorylation site in the 176R (19 kDa) early region 1B protein of human adenovirus type 5

1989 • 10 citations