Amylin gene promoter mutations predispose to Type 2 diabetes in New Zealand Maori

Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients.

1987 • 1,264 citations

TRANSFAC: an integrated system for gene expression regulation

2000 • 1,236 citations

Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation.

1990 • 782 citations

Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus

1999 • 285 citations

Polynesian origins: Insights from the Y chromosome

2000 • 161 citations

Missense Mutation of Amylin Gene (S20G) in Japanese NIDDM Patients

1996 • 147 citations

S20G Mutant Amylin Exhibits Increased in Vitro Amyloidogenicity and Increased Intracellular Cytotoxicity Compared to Wild-Type Amylin

2000 • 135 citations

mtDNA lineage analyses: Origins and migrations of Micronesians and Polynesians

2000 • 113 citations

Identification of cis- and trans-Active Factors Regulating Human Islet Amyloid Polypeptide Gene Expression in Pancreatic β-Cells

1997 • 87 citations

Novel susceptibility gene for late-onset NIDDM is localized to human chromosome 12q.

1998 • 73 citations

Prevalence of diabetes mellitus and impaired glucose tolerance in a New Zealand multiracial workforce.

1991 • 71 citations

Intracellular Amyloidogenesis by Human Islet Amyloid Polypeptide Induces Apoptosis in COS-1 Cells

1999 • 69 citations

Functional consequences of mutations in the MODY4 gene (IPF1) and coexistence with MODY3 mutations

2001 • 59 citations

The islet amyloid polypeptide (amylin) gene S20G mutation in Chinese subjects: Evidence for associations with type 2 diabetes and cholesterol levels

2001 • 57 citations

Pancreatic pathology in non-insulin dependent diabetes (NIDDM)

1995 • 53 citations

Prevalence of Variants in Candidate Genes for Type 2 Diabetes Mellitus in The Netherlands: The Rotterdam Study and the Hoorn Study

1999 • 50 citations

Pathogenesis of non-insulin-dependent (type II) diabetes mellitus (NIDDM) – genetic predisposition and metabolic abnormalities

1999 • 30 citations

Prevalence of known diabetes in a multiethnic community.

1994 • 29 citations

Diabetic Nephropathy and Microalbuminuria in the Community: The South Auckland Diabetes Survey

1994 • 29 citations

Islet amyloid polypeptide gene: no evidence of abnormal promoter region in thirty-five type 2 diabetic patients

1994 • 9 citations

Islet amyloid polypeptide (IAPP) gene analysis in a Japanese diabetic with marked islet amyloid deposition

1992 • 5 citations