[6] Synthetic approaches to continuous assays of retroviral proteases

Novel Fluorogenic Substrates for Assaying Retroviral Proteases by Resonance Energy Transfer

1990 • 589 citations

Sensitive substrates for human leukocyte and porcine pancreatic elastase: A study of the merits of various chromophoric and fluorogenic leaving groups in assays for serine proteases

1979 • 270 citations

HIV-1 protease specificity of peptide cleavage is sufficient for processing of gag and pol polyproteins

1988 • 269 citations

Sensitive, soluble chromogenic substrates for HIV-1 proteinase.

1990 • 200 citations

A simple, continuous fluorometric assay for HIV protease

1990 • 198 citations

Inhibition of retroviral protease activity by an aspartyl proteinase inhibitor

1987 • 184 citations

Human immunodeficiency virus protease

1989 • 175 citations

Studies on the Specificity of Pepsin^*

1967 • 125 citations

Synthetic peptides as substrates and inhibitors of human immune deficiency virus-1 protease.

1988 • 122 citations

A Continuous Fluorescence Assay of Renin Activity

1993 • 84 citations

Design and synthesis of new fluorogenic HIV protease substrates based on resonance energy transfer

1990 • 64 citations

Fluorescence determination of carboxypeptidase A activity based on electronic energy transfer

1972 • 61 citations

Two-step binding mechanism for HIV protease inhibitors

1992 • 59 citations

Retrovirus protease characterized as a dimeric aspartic proteinase

1989 • 50 citations

Continuous spectrophotometric assay for retroviral proteases of HIV-1 and AMV

1989 • 49 citations

New hydroxyethylamine HIV protease inhibitors that suppress viral replication

1992 • 43 citations

Designing of Peptide Substrates

1978 • 43 citations

Standards in Fluorescence Spectrometry

1982 • 42 citations

Chromophoric peptide substrates for the spectrophotometric assay of HIV-1 protease

1990 • 38 citations

Fluorescence‐based continuous assay for the aspartyl protease of human immunodeficiency virus‐1

1990 • 22 citations

Automated synthesis of fluorogenic protease substrates: design of probes for alzheimer's disease-associated proteases

1992 • 17 citations

Assay Systems for HIV-1 Proteinase and Their Use for Evaluation of Inhibitors

1991 • 6 citations