Ox-LDL induces apoptosis in human coronary artery endothelial cells: role of PKC, PTK, bcl-2, and Fas

Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction

1979 • 27,693 citations

Involvement of the Superoxide Anion Radical in the Autoxidation of Pyrogallol and a Convenient Assay for Superoxide Dismutase

1974 • 9,660 citations

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

1993 • 3,465 citations

Mechanisms and Genes of Cellular Suicide

1995 • 2,514 citations

The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation

1995 • 1,979 citations

Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

1993 • 1,692 citations

Reperfusion injury induces apoptosis in rabbit cardiomyocytes.

1994 • 1,431 citations

Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA

1993 • 758 citations

Prevention of Programmed Cell Death of Sympathetic Neurons by the bcl-2 Proto-Oncogene

1992 • 724 citations

Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques.

1994 • 697 citations

Hypoxia induces apoptosis with enhanced expression of Fas antigen messenger RNA in cultured neonatal rat cardiomyocytes.

1994 • 560 citations

Oxygen-derived radicals: a link between reperfusion injury and inflammation.

1987 • 389 citations

Activation of cyclin A-dependent protein kinases during apoptosis.

1994 • 352 citations

Neutrophil depletion limited to reperfusion reduces myocardial infarct size after 90 minutes of ischemia. Evidence for neutrophil-mediated reperfusion injury.

1989 • 308 citations

Determination of the mechanism of free radical generation in human aortic endothelial cells exposed to anoxia and reoxygenation.

1994 • 251 citations

Induction of Apoptosis by Pyrrolidinedithiocarbamate and N-Acetylcysteine in Vascular Smooth Muscle Cells

1996 • 248 citations

Endothelial Cell Death Induced by Tumor Necrosis Factor-α Is Inhibited by the Bcl-2 Family Member, A1

1996 • 247 citations

Neutrophils as potential participants in acute myocardial ischemia: Relevance to reperfusion

1988 • 240 citations

Specific Cleavage of α-Fodrin during Fas- and Tumor Necrosis Factor-induced Apoptosis Is Mediated by an Interleukin-1β-converting Enzyme/Ced-3 Protease Distinct from the Poly(ADP-ribose) Polymerase Protease

1996 • 211 citations

Vitamin C and E prevent lipopolysaccharide-induced apoptosis in human endothelial cells by modulation of Bcl-2 and Bax

1996 • 185 citations

Oxidized LDL Decreases <scp>l</scp> -Arginine Uptake and Nitric Oxide Synthase Protein Expression in Human Platelets

1996 • 178 citations

Tumor necrosis factor-alpha is released from the isolated heart undergoing ischemia and reperfusion

1996 • 169 citations

A simple and repid method for detection of apoptosis in human cells

1992 • 163 citations

Human transplant coronary artery disease: pathological evidence for Fas-mediated apoptotic cytotoxicity in allograft arteriopathy.

1996 • 149 citations

Oxysterols Induced Apoptosis in Cultured Smooth Muscle Cells through CPP32 Protease Activation and bcl-2 Protein Downregulation

1996 • 145 citations

Calcium-mediated damage during post-ischaemic reperfusion

1988 • 144 citations

The Role of Oxidized Low Density Lipoprotein in Atherogenesis

1996 • 138 citations

APOPTOSIS IN HUMAN MONOCYTE-MACROPHAGES EXPOSED TO OXIDIZED LOW DENSITY LIPOPROTEIN

1996 • 137 citations

Necrosis and apoptosis induced by oxidized low density lipoproteins occur through two calcium‐dependent pathways in lymphoblastoid cells

1994 • 120 citations

Oxidized LDL Induces Apoptosis in Cultured Smooth Muscle Cells: A Possible Role for 7-Ketocholesterol

1996 • 115 citations

Myocardial infarct extension during reperfusion after coronary artery occlusion: Pathologic evidence

1993 • 111 citations

Apoptosis in decidual tissue regression and reorganization.

1994 • 107 citations

Transforming Growth Factor β1 Induces Apoptotic Cell Death in Cultured Human Umbilical Vein Endothelial Cells with Down-Regulated Expression of BCL-2

1995 • 106 citations

Apoptosis and Free Radicals

1994 • 87 citations

Superoxide radical-mediated endothelial injury and vasoconstriction of rat thoracic aortic rings.

1990 • 84 citations

bcl-2 Gene Prevents Apoptosis of Basic Fibroblast Growth Factor-Deprived Murine Aortic Endothelial Cells

1994 • 63 citations

Neutrophil Adherence to Rat Cardiac Myocyte by Proinflammatory Cytokines

1994 • 60 citations

Transient reduction of autoantibodies against oxidized ldl in patients with acute myocardial infarction

1995 • 54 citations

Role of protein tyrosine phosphorylation in H2O2-induced activation of endothelial cell phospholipase D

1996 • 49 citations

Oxidized Low Density Lipoproteins Alter Macrophage Lipid Uptake, Apoptosis, Viability and Nitric Oxide Synthesis

1996 • 40 citations

Induction of apoptosis and secondary necrosis in rat dorsal root ganglion cell cultures by oxidized low density lipoprotein

1996 • 29 citations

Endothelial dysfunction and dyslipidemia: possible effects of lipid lowering and lipid modifying therapy

1994 • 24 citations

Oxidized low-density lipoproteins and microvascular responses to ischemia-reperfusion

1996 • 21 citations

Low-density lipoproteins inhibit histamine and NaNO2 relaxations of the coronary vasculature and reduce contractile function in isolated rat hearts

1995 • 20 citations

Protein Kinase C in Angiotensin II Signalling in Neonatal Rat Cardiac Fibroblasts

1995 • 16 citations

[Oxidative stress and apoptosis].

1996 • 8 citations