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Suppression of the formation of polyamines and macromolecules by <scp>dl</scp>-α-difluoromethylornithine and methylglyoxal bis(guanylhydrazone) in phytohaemagglutinin-activated human lymphocytes

Data up to Jan 2025

Published1979
Citations88
References25

Total Citations Per Year

Abstract

References (25)

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Polyamines in rapid growth and cancer

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1976 • 1,203 citations

Anti-proliferative properties of DL-α-difluoromethyl ornithine in cultured cells. A consequence of the irreversible inhibition of ornithine decarboxylase

1978 • 398 citations

Use of the Dansyl Reaction in Biochemical Analysis

1970 • 373 citations

Methyl glyoxal bis(guanylhydrazone) as a potent inhibitor of mammalian and yeast S-adenosylmethionine decarboxylases

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Possible Synthesis of Polyribonucleotides of Known Base-triplet Sequences

1965 • 180 citations

Increased cellular levels of spermidine or spermine are required for optimal DNA synthesis in lymphocytes activated by concanavalin A.

1975 • 168 citations

Polyamine accumulation during lymphocyte transformation and its relation to the synthesis, processing, and accumulation of ribonucleic acid

1973 • 119 citations

Polyamine synthesis during lymphocyte activation

1973 • 118 citations

Inhibition of polyamine accumulation and deoxyribonucleic acid synthesis in regenerating rat liver

1976 • 76 citations

Effect of inhibition of spermidine formation on protein and nucleic acid synthesis during lymphocyte activation

1973 • 75 citations

Induction of thymidine kinases in phytohaemagglutinin-stimulated human lymphocytes

1977 • 75 citations

Determination of polyamines in urine

1973 • 71 citations

Proliferation of human peripheral blood lymphocytes induced by A23187, a streptomyces antibiotic

1976 • 69 citations

Early Effects of Phytohaemagglutinin on Lymphocyte RNA Synthesis

1968 • 62 citations

DNA Synthesis in HeLa Cells and Isolated Nuclei after Treatment with an Inhibitor of Spermidine Synthesis, Methyl Glyoxal Bis(guanylhydrazone)

1977 • 54 citations

Inhibition of the synthesis of polyamines and DNA in activated lymphocytes by a combination of alpha-methylornithine and methylglyoxal bis(guanylhydrazone).

1977 • 54 citations

On the Synthesis of RNA in Lymphocytes Stimulated by Phytohemagglutinin

1969 • 48 citations

Regulation of Macromolecular Synthesis by Putrescine in a Conditional Escherichia coli Putrescine Auxotroph

1972 • 45 citations

METABOLISM OF RHESUS MONKEY SPERMATOZOA

1968 • 41 citations

The antimitochondrial action of 2-choloro-4', 4"-bis(2-imidazolin-2-yl)terephthalanilide and methylglyoxal bis(guanylhydrazone).

1966 • 40 citations

Thymidine transport in phytohaemagglutinin-stimulated pig lymphocytes

1975 • 29 citations

Increased rate of RNA-polyadenylation

1978 • 27 citations

Suppression of phytohemagglutinin-induction of thymidine uptake in guinea pig lymphocytes by methylglyoxal bis(guanylhydrazone) treatment

1977 • 11 citations

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