Gene structure and transcription in mouse cells with extensively demethylated DNA.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A procedure for the isolation of deoxyribonucleic acid from micro-organisms

1961 • 11,554 citations

Genomic sequencing.

1984 • 8,343 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination

1977 • 3,548 citations

Expression of a single transfected cDNA converts fibroblasts to myoblasts

1987 • 3,373 citations

Cellular differentiation, cytidine analogs and DNA methylation

1980 • 1,803 citations

Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division.

1973 • 1,126 citations

DNA METHYLATION AND GENE ACTIVITY

1983 • 1,115 citations

Amount and distribution of 5-methylcytosine in human DNA from different types of tissues or cells

1982 • 1,002 citations

DNA methylation affects the formation of active chromatin

1986 • 588 citations

Chromatin structure of endogenous retroviral genes and activation by an inhibitor of DNA methylation

1981 • 475 citations

Altering gene expression with 5-azacytidine

1985 • 408 citations

Methylation of the Hprt gene on the inactive X occurs after chromosome inactivation

1987 • 363 citations

Transcriptionally active chromatin

1984 • 361 citations

Genomic footprinting reveals cell type-specific DNA binding of ubiquitous factors

1987 • 356 citations

Sequence of a cDNA clone encoding mouse glial fibrillary acidic protein: structural conservation of intermediate filaments.

1984 • 352 citations

DNA methylation, biochemistry, and biological significance

1984 • 343 citations

The complete sequence of a chromosomal mouse α-globin gene reveals elements conserved throughout vertebrate evolution

1979 • 317 citations

DNA methylation patterns Formation and function

1984 • 312 citations

Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene.

1987 • 241 citations

Effect of regional DNA methylation on gene expression.

1985 • 232 citations

Hemimethylation prevents DNA replication in E. coli

1987 • 227 citations

Tissue-specific differences in DNA methylation in various mammals

1983 • 204 citations

Cytosine methylation does not affect binding of transcription factor Sp1.

1988 • 201 citations

Structure of amplified normal and variant dihydrofolate reductase genes in mouse sarcoma S180 cells.

1982 • 184 citations

Gene expression: DNA methylation — how important in gene control?

1984 • 178 citations

Dispersion of α-like globin genes of the mouse to three different chromosomes

1981 • 171 citations

The effect of sequence specific DNA methylation on restriction endonuclease cleavage

1981 • 120 citations

A Portable Signal Causing Faithful DNA Methylation de Novo in Neurospora crassa

1987 • 93 citations

Regulation of mouse satellite DNA replication time.

1988 • 84 citations

DNA methylation in 5-aza-2'-deoxycytidine-resistant variants of C3H 10T1/2 C18 cells.

1984 • 76 citations

DiFferential Nuclear Protein Binding to 5-Azacytosine-Containing DNA as a Potential Mechanism for 5-Aza-2′-Deoxycytidine Resistance

1987 • 75 citations

Gene Activation by 5-Azacytidine

1984 • 74 citations

Gene Methylation Patterns and Expression

1984 • 71 citations

Primary DNA Sequence Determines Sites of Maintenance and De Novo Methylation by Mammalian DNA Methyltransferases

1986 • 65 citations

Differential nuclear protein binding to 5-azacytosine-containing DNA as a potential mechanism for 5-aza-2'-deoxycytidine resistance.

1987 • 49 citations

Primary DNA sequence determines sites of maintenance and de novo methylation by mammalian DNA methyltransferases.

1986 • 43 citations

Transcriptionally active chromatin

1983 • 40 citations

DNA methylation: sequences flanking C-G pairs modulate the specificity of the human DNA methylase

1985 • 40 citations

Effects of 5-azacytidine on methylation and expression of specific DNA sequences in C3H 10T1/2 cells.

1984 • 39 citations

Effects of 5-azacytidine on expression of endogenous retrovirus-related sequences in C3H 10T1/2 cells

1986 • 39 citations

Specific Factors Binding to the Late E2A Promoter Region of Adenovirus Type 2 DNA: No Apparent Effects of 5′-CCGG-3′ Methylation

1987 • 26 citations

Deleted Work

1955 • 0 citations