Regulation of human lung fibroblast phenotype and function by vitronectin and vitronectin integrins

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

SUBEPITHELIAL FIBROSIS IN THE BRONCHI OF ASTHMATICS

1989 • 1,151 citations

Synergistic Roles for Receptor Occupancy and Aggregation in Integrin Transmembrane Function

1995 • 900 citations

Signal transduction and signal modulation by cell adhesion receptors: the role of integrins, cadherins, immunoglobulin-cell adhesion molecules, and selectins.

1998 • 834 citations

Bidirectional signaling between the cytoskeleton and integrins

1999 • 765 citations

The Adaptor Protein Shc Couples a Class of Integrins to the Control of Cell Cycle Progression

1996 • 739 citations

Myofibroblasts and Subepithelial Fibrosis in Bronchial Asthma

1990 • 670 citations

Integrin signaling and cell growth control

1998 • 655 citations

Mechanisms of Myofibroblast Activity and Phenotypic Modulation

1999 • 580 citations

The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins. Role of alpha v beta 3 in smooth muscle cell migration to osteopontin in vitro.

1995 • 508 citations

Myofibroblasts and their role in lung collagen gene expression during pulmonary fibrosis. A combined immunohistochemical and in situ hybridization study.

1994 • 470 citations

Wound repair in the context of extracellular matrix

1994 • 435 citations

Heterogeneity of myofibroblast phenotypic features: an example of fibroblastic cell plasticity

1994 • 431 citations

Temporal relationships of F-actin bundle formation, collagen and fibronectin matrix assembly, and fibronectin receptor expression to wound contraction.

1990 • 363 citations

Myofibroblast involvement in the allergen-induced late response in mild atopic asthma.

1997 • 277 citations

Actin cytoskeleton organization in response to integrin-mediated adhesion

1999 • 159 citations

Regulation of lung fibroblast alpha-smooth muscle actin expression, contractile phenotype, and apoptosis by IL-1beta.

1997 • 102 citations

The αvβ5 integrin functions as an endocytic receptor for vitronectin

1998 • 99 citations

The alpha v beta 5 integrin receptor regulates receptor-mediated endocytosis of vitronectin

1993 • 94 citations

Ligation of Integrin α5β1 Is Required for Internalization of Vitronectin by Integrin αvβ3

1997 • 66 citations

Vitronectin in Bronchoalveolar Lavage Fluid Is Increased in Patients with Interstitial Lung Disease

1991 • 43 citations

Role of the myofibroblast in pulmonary fibrosis.

1996 • 42 citations

Vitronectin regulates smooth muscle contractility via αv and β1 integrin(s)

1998 • 39 citations

Interaction of lipopolysaccharide with human small intestinal lamina propria fibroblasts favors neutrophil migration and peripheral blood mononuclear cell adhesion by the production of proinflammatory mediators and adhesion molecules

1999 • 33 citations

Elevated Levels of Bronchoalveolar Lavage Vitronectin in Hypersensitivity Pneumonitis

1993 • 23 citations

The expression of α2β1 integrin and α smooth muscle actin in fibroblasts grown on collagen

1998 • 22 citations

Integrin receptor involvement in actin cable formation in an in vitro model of events associated with wound contraction

1997 • 21 citations

Functional partitioning of β1 integrins revealed by activating and inhibitory mAbs

1997 • 15 citations

Deleted Work

1955 • 0 citations