Large-scale preparation of ribulosebisphosphate carboxylase from a recombinant system in Escherichia coli characterized by extreme plasmid instability

Experiments in molecular genetics

1972 • 28,260 citations

Novel Method for Detection of β-Lactamases by Using a Chromogenic Cephalosporin Substrate

1972 • 1,857 citations

Partitioning of bacterial plasmids during cell division: a cis-acting locus that accomplishes stable plasmid inheritance

1980 • 335 citations

Cytoplasmic Inclusion Bodies in Escherichia coli Producing Biosynthetic Human Insulin Proteins

1982 • 308 citations

A PERSPECTIVE ON THE APPLICATION OF GENETIC ENGINEERING: STABILITY OF RECOMBINANT PLASMID

1981 • 267 citations

Copy number and the stability of 2-micron circle-based artificial plasmids of Saccharomyces cerevisiae

1984 • 190 citations

The Influence of the Growth Environment on the Stability of a Drug Resistance Plasmid in Escherichia coli K12

1979 • 189 citations

Nucleotide sequence of the ribulosebisphosphate carboxylase gene from Rhodospirillum rubrum

1984 • 148 citations

Maintenance and genetic stability of vector plasmids pBR322 and pBR325 in Escherichia coli K12 strains grown in a chemostat

1981 • 141 citations

Cloning and expression of the Rhodospirillum rubrum ribulosebisphosphate carboxylase gene in E. coli

1984 • 137 citations

Maintenance of some ColE1-type plasmids in chemostat culture

1980 • 126 citations

Studies of mouse mitochondrial DNA in escherichia coli: Structure and function of the eucaryotic-procaryotic chimeric plasmids

1975 • 111 citations

Replication of R-factor R1 in Scherichia coli K-12 at different growth rates

1975 • 108 citations

The use of a partition locus to increase stability of tryptophan-operon-bearing plasmids in Escherichia coli

1983 • 91 citations

Thiol-beta-lactamase: replacement of the active-site serine of RTEM beta-lactamase by a cysteine residue.

1982 • 84 citations

Phenotypic Stability of trp Operon Recombinant Plasmids in Escherichia coli

1980 • 64 citations

Instability kinetics of trp operon plasmid ColEl‐trp in recombinant Escherichia coli MV 12[pVH5] and MV 12trp R [pVH5]

1984 • 53 citations

Inheritability of plasmids and population dynamics of cultured cells.

1975 • 45 citations

Instability in tyrR Strains of Plasmids Carrying the Tyrosine Operon: Isolation and Characterization of Plasmid Derivatives with Insertions or Deletions

1980 • 43 citations

TOL plasmid in Pseudomonas aeruginosa PAO: thermosensitivity of self-maintenance and inhibition of host cell growth

1978 • 36 citations

Immunocytochemical demonstration of human proinsulin chimeric polypeptide within cytoplasmic inclusion bodies of Escherichia coli.

1983 • 32 citations

Maintenance of the bacteriocinogenic plasmid clo DF13 in Escherichia coli cells

1982 • 22 citations