Characterization and immunohistochemical localization of alpha 2-macroglobulin receptor (low-density lipoprotein receptor-related protein) in human brain.

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

1981 • 14,396 citations

Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology

1988 • 3,984 citations

A rapid, sensitive, and specific method for the determination of protein in dilute solution

1973 • 2,518 citations

The interaction of α2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism

1973 • 1,062 citations

Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system.

1985 • 786 citations

Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain.

1987 • 696 citations

Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor.

1990 • 666 citations

Lipoprotein lipase enhances the binding of chylomicrons to low density lipoprotein receptor-related protein.

1991 • 627 citations

39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor.

1991 • 586 citations

Interleukin‐6 and α‐2‐macroglobulin indicate an acute‐phase state in Alzheimer's disease cortices

1991 • 484 citations

[2] Subcellular fractionation of rat liver

1974 • 438 citations

Clearance and binding of two electrophoretic “fast” forms of human alpha 2-macroglobulin.

1981 • 398 citations

Evidence that the newly cloned low‐density‐lipoprotein receptor related protein (LRP) is the α₂‐macroglobulin receptor

1990 • 320 citations

Proteolytic processing of the 600 kd low density lipoprotein receptor-related protein (LRP) occurs in a trans-Golgi compartment.

1990 • 279 citations

The human alpha 2-macroglobulin receptor: identification of a 420-kD cell surface glycoprotein specific for the activated conformation of alpha 2-macroglobulin.

1990 • 268 citations

Primary structure of alpha 2-macroglobulin receptor-associated protein. Human homologue of a Heymann nephritis antigen

1991 • 230 citations

Lipoprotein Uptake by Neuronal Growth Cones in Vitro

1987 • 209 citations

Analysis of ligand recognition by the purified alpha 2-macroglobulin receptor (low density lipoprotein receptor-related protein). Evidence that high affinity of alpha 2-macroglobulin-proteinase complex is achieved by binding to adjacent receptors

1991 • 186 citations

Endothelial Cell‐Astrocyte Interactions

1988 • 140 citations

An alpha 2-macroglobulin receptor-dependent mechanism for the plasma clearance of transforming growth factor-beta 1 in mice.

1991 • 139 citations

Production of colony‐stimulating factor‐1 (CSF‐1) by mouse astroglia in vitro

1990 • 114 citations

Purification of the Rat Hepatic α2-Macroglobulin Receptor as an Approximately 440-kDa Single Chain Protein

1989 • 112 citations

Protease nexin-1. Localization in the human brain suggests a protective role against extravasated serine proteases.

1990 • 111 citations

The receptor-binding domain of human alpha 2-macroglobulin. Isolation after limited proteolysis with a bacterial proteinase.

1986 • 103 citations

Domain structure of human α₂‐macroglobulin

1986 • 102 citations

Binding of tumor necrosis factor alpha to activated forms of human plasma alpha 2 macroglobulin.

1991 • 94 citations

Alpha 2‐macroglobulin synthesis in interleukin‐6‐stimulated human neuronal (SH‐SY5Y neuroblastoma) cells Potential significance for the processing of Alzheimer β‐amyloid precursor protein

1991 • 93 citations

Purification of the human placental α₂‐macroglobulin receptor

1989 • 91 citations

Localization of mRNA for low density lipoprotein receptor and a cholesterol synthetic enzyme in rabbit nervous system by in situ hybridization.

1988 • 81 citations

Synthesis of plasma proteins in fetal, adult, and neoplastic human brain tissue

1986 • 80 citations

Alpha 2-macroglobulin: a protein at the interface of fibrinolysis and cellular growth regulation.

1992 • 51 citations

Binding of transforming growth factor-β1 to methylamine-modified α2-macroglobulin and to binary and ternary α2-macroglobulin-proteinase complexes

1992 • 37 citations

Modulatory effects of aluminum, calcium, lithium, magnesium, and zinc ions on [ 3H]MK-801 binding in human cerebral cortex

1989 • 27 citations

Alpha 2-macroglobulin is the primary inhibitor of miniplasmin in vitro and in vivo in the mouse. Comparison with alpha 2-antiplasmin in simultaneous reaction experiments.

1988 • 17 citations