Histamine Release by Basic Compounds

The Pharmacological Basis of Therapeutics

1941 • 2,217 citations

The Blood Vessels of the Human Skin and Their Responses.

1928 • 882 citations

Manual of Pharmacology

1957 • 548 citations

Vascular reactions to histamine, histamine‐liberator and leukotaxine in the skin of guinea‐pigs

1952 • 535 citations

The mast cells

1965 • 520 citations

The Blood Vessels of the Human Skin and Their Responses

1928 • 496 citations

The mast cells

1959 • 249 citations

The release of histamine and 5‐hydroxytryptamine (serotonin) from platelets by antigen‐antibody reactions (in vitro)

1955 • 241 citations

Reduction of tissue histamine by compound 48/80

1953 • 241 citations

Histamine release by compounds of simple chemical structure.

1957 • 241 citations

Release of histamine from skin and muscle in the cat by opium alkaloids and other histamine liberators

1951 • 240 citations

The liberation of histamine by certain organic bases

1949 • 213 citations

Evidence That Serotonin Has a Role in Brain Function

1955 • 210 citations

Further Observations on the Disruption of Rat Mesentery Mast Cells Caused by Compound 48/80, Antigen‐Antibody Reaction, Lecithinase A and Decylamine

1960 • 203 citations

Isolation of “biologically intact” mast cells

1959 • 185 citations

Inhibition of the anaphylactic reaction

1957 • 183 citations

Tissue mast cells. Studies with a histamine‐liberator of low toxicity (compound 48/80)

1955 • 166 citations

The effect of calcium and pH on the anaphylactic reaction

1958 • 162 citations

CYTOLOGICAL AND PHARMACOLOGICAL OBSERVATIONS ON THE RELEASE OF HISTAMINE BY MAST CELLS

1954 • 160 citations

Release of 5‐hydroxytryptamine and histamine from tissues of the rat

1957 • 158 citations

Ciba Foundation Symposium on Histamine

1957 • 154 citations

FORMATION OF BRADYKININ IN ANAPHYLACTIC AND PEPTONE SHOCK

1950 • 153 citations

Evidence for enzymatic histamine release from isolated rat mast cells

1961 • 149 citations

The effects of histamine‐liberators on the mast cells of the rat

1953 • 148 citations

A Family of Long-Acting Depressors

1949 • 140 citations

Effect of temperature on the anaphylactic reaction

1957 • 127 citations

Liberation of histamine from the skeletal muscle by curare

1939 • 116 citations

THE EFFECTS OF MUSCLE RELAXANTS OTHER THAN MUSCULAR RELAXATION

1959 • 106 citations

A comparison of the effects of anaphylactic shock and of chemical histamine releasers

1952 • 102 citations

The Mechanism of Histamine Release in Anaphylactic Reaction in Guinea Pig and Rat

1960 • 102 citations

STUDIES ON THE MECHANISM OF HYPERSENSITIVITY PHENOMENA

1959 • 101 citations

THE HISTAMINE-LIKE ACTION OF CURANE AND TUBOCURARINE INJECTED INTRACUTANEOUSLY AND INTRA-ARTERIALLY IN MAN

1946 • 96 citations

RELEASE OF HISTAMINE BY TRYPTAMINE AND 5–HYDROXYTRYPTAMINE

1953 • 94 citations

THE FALL OF BLOOD PRESSURE CAUSED BY INTRAVENOUS MORPHINE IN THE RAT AND THE CAT

1952 • 92 citations

Regional variations of increased permeability of skin capillaries induced by a histamine liberator and their relation to the histamine content of the skin

1953 • 86 citations

Protamine-like Property of Compounds 48/80 and Stilbamidine and Their Action on Mast Cells.

1953 • 84 citations

Evidence for Energy‐Requiring Processes in Histamine Release and Mast Cell Degranulation in Rat Tissues Induced by Compound 48/80

1961 • 82 citations

ELECTRON MICROSCOPY OF THE TISSUE MAST CELL

1957 • 78 citations

Effect of antigen and octylamine on mast cells and histamine content of sensitized guinea‐pig tissues

1959 • 77 citations

Intracellular Distribution of Histamine

1954 • 74 citations

Nature of the Secretory Activity of the Mast Cell

1958 • 73 citations

MAST CELLS AS SOURCES OF TISSUE HISTAMINE

1955 • 71 citations

Fate of Shed Mast Cell Granules.

1956 • 70 citations

THE RELEASE OF 5‐HYDROXYTRYPTAMINE BY HISTAMINE LIBERATORS

1956 • 69 citations

QUANTITATIVE DETERMINATION OF MAST CELL FRAGMENTATION BY COMPOUND 48/80

1954 • 68 citations

Inhibition of Histamine Release in Experimental Diabetes

1957 • 65 citations

MAST CELL DEGRANULATION AND HISTAMINE RELEASE OBSERVED IN A NEW IN VITRO SYSTEM

1960 • 64 citations

INHIBITION OF MAST CELL DISRUPTION AND HISTAMINE RELEASE IN RAT ANAPHYLAXIS IN VITRO. COMPARISON WITH COMPOUND 48/80

1960 • 63 citations

TISSUE REACTIONS TO ANAPHYLACTIC AND ANAPHYLACTOID STIMULI; PROTEOLYSIS AND RELEASE OF HISTAMINE AND HEPARIN

1955 • 63 citations

Mechanism of tho Release by Componnd 48/80 of Histamine and of a Lipid‐Soluble Smooth Muscle Stimulating Principle (“SRS”)

1959 • 63 citations

Biochemical and electron microscopic study of particles isolated from mastocytoma cells.

1959 • 62 citations

Antihistamine Substances

1948 • 60 citations

The role of histamine in cutaneous antigen‐antibody reactions in the rat

1955 • 60 citations

The effects of amines on oxidations of the brain

1933 • 57 citations

Effect of ACTH and cortisone upon an anaphylactoid reaction.

1949 • 54 citations

Histamine release by horse serum from skin of the sensitized dog and non‐sensitized cat

1952 • 53 citations

The effect of histamine and a histamine‐releasing agent (compound 48/80) on wound healing

1959 • 51 citations

COMPARISON OF HISTAMINE RELEASE BY COMPOUND 48/80 AND OCTYLAMINE IN PERFUSED TISSUES

1954 • 51 citations

The release of histamine by d‐tubocurarine from the isolated diaphragm of the rat

1949 • 50 citations

QUANTITATIVE MEASUREMENT OF THE HISTAMINE‐RELEASING ACTIVITY OF A SERIES OF MONO‐ALKYL‐AMINES USING MINCED GUINEA‐PIG LUNG

1953 • 50 citations

The ganglionic blocking action of thiophanium derivatives.

1949 • 49 citations

Histamine release by adrenaline and d‐tubocurarine in the human subject

1953 • 47 citations

Release of Histamine from Mast Cells by Tissue Extracts

1958 • 46 citations

Metabolic studies on the release of histamine by compound 4880 in the rat diaphragm

1961 • 45 citations

THE RELEASE OF HISTAMINE BY POLYMYXIN B AND POLYMYXIN E

1955 • 44 citations

Histamine release by antihistamines.

1953 • 43 citations

ANAPHYLAXIS AND HISTAMINE RELEASE IN THE RABBIT

1953 • 43 citations

Histamine Liberation in vitro and Mode of Binding of Histamine in Tissues

1954 • 43 citations

The Pharmacology and Therapeutics of Curare and its Constituents

1935 • 42 citations

Untersuchungen über den Histamingehalt des Blutes bei Infusion von Adrenalin und Histamin

1940 • 42 citations

STUDIES ON THE FUNCTIONAL INTERRELATIONSHIP OF FIBROBLASTS AND GROUND SUBSTACE MUCOPOLYSACCHARIDES

1958 • 41 citations

The chemical nature of Darmstoff

1957 • 41 citations

ACTION OF COMPOUND 48/80 ON THE MAST CELLS AND HISTAMINE CONTENT OF GUINEA‐PIG TISSUES

1956 • 40 citations

FURTHER STUDIES ON THE ROLE OF PROTEASES IN THE ALLERGIC REACTION

1961 • 39 citations

THE INFLUENCE OF AN ANTIHISTAMINE DRUG ON THE RELEASE OF HISTAMINE IN THE UNANAESTHETIZED DOG

1951 • 39 citations

Effect of antigen and organic bases on intracellular histamine in guinea‐pig lung

1956 • 38 citations

A Comparison of Mast‐Cell Reactions in the Rat, Hamster and Guinea Pig

1960 • 37 citations

THE RELEASE OF HISTAMINE BY PETHIDINE, ATROPINE, QUININE, AND OTHER DRUGS

1952 • 37 citations

The simultaneous release of histamine and a histamine‐destroying factor during anaphylaxis in rats

1961 • 37 citations

Influence of oxidative phosphorylation inhibitors on the histamine release in the anaphylactic reactionin vitro

1958 • 37 citations

The responses of the heart rate and the systolic blood pressure to a series of sympathomimetic amines in the unanaesthetized, atropinized bitch

1950 • 36 citations

THE INTRACELLULAR DISTRIBUTION OF HISTAMINE IN DOG'S LIVER

1954 • 35 citations

A STUDY OF THE BRONCHOCONSTRICTOR AND HYPOTENSIVE ACTIONS OF CURARIZING DRUGS

1947 • 34 citations

THE ESTIMATION AND COMPARISON OF HISTAMINE RELEASE BY MUSCLE RELAXANTS IN MAN

1952 • 34 citations

Nature of the hypotensive action of a thiophanium derivative (Ro 2-2222) in dogs.

1952 • 34 citations

Sources of Urinary Histamine in the Rat

1954 • 32 citations

�ber Komplexe von Heparin mit Histamin und anderen Di- und Polyaminen

1956 • 32 citations

THE EFFECTS OF RESERPINE AND COMPOUND 48/80 ON THE RELEASE OF AMINES FROM THE MAST CELLS OF RATS

1956 • 32 citations

Mechanism of Release from Mast Cells

1961 • 31 citations

Extraction of a Heparin-like Substance from Mast Cell Granules in Mouse Connective Tissue

1953 • 30 citations

EFFECT OF CHAIN LENGTH OF ALIPHATIC AMINES ON HISTAMINE POTENTIATION AND RELEASE

1957 • 30 citations

Histamine in Mast Cell Granules

1955 • 29 citations

The Distribution of Mast-Cells in the Digestive Tract of Laboratory Animals: Its Bearings on the Problem of the Location of Histamine in Tissues

1956 • 29 citations

Dynamics of Release of Histamine from Tissue Mast Cell

1958 • 29 citations

Release of histamine by the histamine liberator compound 48/80 in cats

1953 • 28 citations

Liberation of endogenous histamine in man

1957 • 28 citations

On certain vascular effects of curare in man: the histamine reaction.

1947 • 28 citations

Binding and Release of Radioactive Histamine in Intact Rats

1954 • 28 citations

Anaphylatoxin, Histamine Depletion and Skin Reactions in the Rat

1955 • 27 citations

TISSUE MAST CELLS

1960 • 27 citations

Histamine liberation in the rat and mouse.

1955 • 26 citations

The effect of reserpine on histamine and serotonin

1959 • 26 citations

The pharmacology of No. 48-80, a long-acting vasodepressor drug.

1953 • 26 citations

Histamine Liberation Produced in the Perfuse Paw of the Cat by 48/80 and Extracts from Jellyfish (Cyanea Capillata) and Eelworm (Ascaris Lumbricoides) from Swine.

1957 • 25 citations

Histamine Release in Rabbit Blood by Simple Molecules, Inhibition and Reaction Rate Studies

1951 • 24 citations

The Influence of Anoxia on 48/80‐Induced Histamine Release from Cat Skin

1960 • 22 citations

Observations on the Toxicity of Stilbamidine

1944 • 22 citations

Histamine – Heparin – Thrombin Chain Mechanism

1948 • 21 citations

Action of histamine liberator compound in the guinea pig

1955 • 21 citations

The Mechanism of the Local Inflammatory Reaction Induced by Compound 48/80 and Dextran in Rats

1961 • 21 citations

MORPHINE AND HISTAMINE RELEASE

1958 • 21 citations

Concerning the Mechanism of Anaphylactic and Tryptic Shock

1941 • 20 citations

Influence of Anaerobic Glycolysis on Release of Histamine in the Guinea Pig and Rat Anaphylactic Reaction in vitro

1961 • 20 citations

THE PHARMACOLOGICAL PROPERTIES OF “LAUDOLISSIN”—A LONG‐ACTING CURARIZING AGENT*

1952 • 20 citations

Studies on the in vitro action of compound 48-80, a formaldehyde condensation product, on rat mast-cells.

1955 • 19 citations

THE RELEASE OF HISTAMINE BY SINOMENINE

1953 • 19 citations

Factors influencing the urinary excretion of histamine in the rat

1954 • 18 citations

ENDERMIC REACTIONS. I

1917 • 18 citations

Effect of adrenocortical hormones on tissue histamine and 5-hydroxytryptamine in the rat.

1962 • 17 citations

Effect of metabolic inhibitors on the release of histamine by anaphylatoxin and by antigenin vitro

1961 • 17 citations

EVALUATION OF TWO SYNTHETIC CURARIZING AGENTS IN CONSCIOUS VOLUNTEERS

1952 • 17 citations

Comparison of the Release of Histamine and 5-Hydroxytryptamine from Tissues of the Rat, Mouse and Hamster

1958 • 16 citations

Effect of catecholamines and their chloro-analogs on the in vitro release of histamine front cells of rat peritoneal fluid

1962 • 16 citations

The release of histamine from rat peritoneal mast cells by compound 48/80: effects of metabolic inhibitors.

1961 • 15 citations

Release of Histamine by Ammonia

1949 • 15 citations

Histamin-Freisetzung in der Lunge durch Reizstoffbeatmung

1937 • 15 citations

HISTAMINE RELEASE AND PAIN PRODUCTION BY XANTHOSINE AND RELATED COMPOUNDS

1957 • 15 citations

THE EFFECT OF COMPOUND 48/80 ON GANGLIONIC TRANSMISSION

1955 • 14 citations

The action of curarine on the respiratory mechanism

1938 • 14 citations

Further studies on hexadimethrine bromide (polybrene)—an antiheparin agent

1959 • 14 citations

In Vitro Release of Histamine from Cat Skin by Compound 48/80

1960 • 14 citations

The effect of compound 48/80 on acid gastric secretion in the cat

1953 • 13 citations

Histamine Release into the Circulation by Meperidine (Demerol(R)).

1961 • 13 citations

EXPERIMENTAL DESIGN FOR BIOASSAY OF A MATERIAL INDUCING STRONG TACHYPHYLACTIC EFFECT (ANAPHYLATOXIN)

1956 • 13 citations

Case of Hypersensitivity to Pethidine in a Woman in Labour

1951 • 12 citations

The role of histamine release for the motor effects of histamine liberators on the guinea‐pig's ileum preparation

1954 • 12 citations

Influence of Antihistamines on Mast Cell Disruption Following X-Irradiation.

1958 • 12 citations

Effect of histamine releasers and of anti-inflammatory drugs on the egg-white edema of rat's hind paws in relation to skin histamine

1958 • 12 citations

Action of histamine on the jugular venous pressure and cerebral circulation of the dog; effects of antihistaminic drugs (pyrilamine and chlorpheniramine) and a histamine liberating agent (48/80 B.W.).

1956 • 12 citations

Liberation of histamine by adrenaline from isolated lung.

1950 • 12 citations

Histamine as a factor in tolerance to levarterenol

1962 • 11 citations

The Sites of Action of some Histamin-Releasing Substances in the Dog

1957 • 11 citations

Effect of reserpine, serotonin, and 5-hydroxytryptophan on rabbit platelet histamine in vivo and in vitro

1960 • 11 citations

Studies on the toxicology of a histamine liberator, compound 48-80.

1959 • 11 citations

HISTAMINE RELEASE DURING CONTROLLED HYPOTENSION WITH ARFONAD

1957 • 10 citations

THE LIBERATION OF HISTAMINE AND HEPARIN BY TUBOCURARINE AND ITS CIRCULATORY EFFECTS IN THE DOG

1950 • 9 citations

Liberation and depletion of histamine from human skin

1956 • 9 citations

MORPHINE “SENSIVITY”

1949 • 9 citations

Chemical Nature and Possible Role of Mediators in Allergic Reactions

1961 • 9 citations

Liberation and depletion of histamine from human skin; comparison of effects of specific antigens and a new histamine liberator, compound 48/80.

1954 • 9 citations

The experimental production of gastric ulcers by histamine-releasing substances

1958 • 9 citations

Effect of Chlorpromazine on Number of Mast Cells and of Certain Formed Elements of Blood

1958 • 9 citations

SOME PHARMACOLOGICAL ACTIONS OF PALUDRINE

1949 • 9 citations

Effect of some antibiotics on rat mast cells in vitro.

1955 • 8 citations

Concerning the mechanism of anaphylactic and tryptic shock

1942 • 8 citations

Bradykinin and Anaphylactic Shock in Dogs

1965 • 8 citations

Der Einfluss verschiedener Psychopharmaka auf den Bluthistamingehalt von Ratten

1959 • 8 citations

Effect of hypothermia on histamine release induced by epinephrine infusion

1960 • 8 citations

Histamine release and its inhibition by antihistamines

1957 • 7 citations

Histamine liberation in the hamster.

1957 • 7 citations

RELEASE OF HISTAMINE BY A SUBSTITUTED BUTYLAMINE (L 1935): COMPARISON WITH COMPOUND 48/80

1955 • 7 citations

CENTRAL EFFECTS PRODUCED BY INJECTION OF 48/80 INTO THE CEREBRAL VENTRICLES OF MICE

1959 • 6 citations

Interaction of Compound 48/80 and Stilbamidine with Strandin.

1961 • 6 citations

The effect of compound 48/80 on the autograft and homograft reaction.

1960 • 6 citations

Fragmentation of Mast Cells Caused by Some Phenothiazine Derivatives.

1957 • 6 citations

SOME EVIDENCE CONCERNING THE MODE OF BINDING OF HISTAMINE

1959 • 5 citations

Untersuchungen an Ionenaustauschmodellen zum Verständnis der Physiologie biogener Amine. Austauschversuche an einem schwefelsäuregruppentragenden Harz zum Verständnis von sogenannten Histaminliberationsvorgängen

1961 • 5 citations

THE EFFECT OF COMPOUND 48/80 ON MAMMALIAN SKELETAL MUSCLE

1955 • 5 citations

Effect of a histamine liberator and of serotonin on plasma pepsinogen in rats.

1960 • 5 citations

Evaluation of Histamine Release in Rats by Analysis of Urine

1955 • 5 citations

Déplétion en histamine et phénomène d’Arthus cutané chez le lapin

1956 • 4 citations

Influence of Compound 48/80, Protamine and Other Substances on Rabbit Blood Basophils in vitro

1959 • 4 citations

An analysis of the histamine-like actions of oxypanamine.

1959 • 4 citations

Cardiovascular and Respiratory Effects of Lethal Doses of Histamine and Compound 48/80 in Rabbits.

1959 • 4 citations

Uber die Wirkung von Diaminodecan auf Mastzellen und basophile Leukozyten

1957 • 3 citations

Effets de l'histamine et des processus d'histamino-libération sur la fonction pulmonaire

1960 • 3 citations

Allergy to Meprobamate with Some Observations Regarding the Tranquilizing Drugs*

1957 • 3 citations

LIBERATEURS ĎHISTAMINE ET INTRADERMO‐REACTION TUBERCULINIQUE CHEZ & Lcar;HOMME

1953 • 3 citations

A study of the hemodynamic actions of histamine and 1,10-diaminodecane in cats.

1954 • 2 citations

BEHAVIOUR OF PRESSURE AND PULSE OF CEREBROSPINAL FLUID IN MAN DURING RELEASE OF HISTAMINE BY COMPOUND 48/80

1960 • 2 citations

INFLUENCE DE LA LIBERATION PHARMACODYNAMIQUE DE L'HISTAMINE CUTANEE SUR LES REACTIONS ANAPHYLACTIOUES LOCALES DE TYPE IMMEDIAT

1958 • 2 citations

[On the histaminic nature of complications caused by disulfiram].

1960 • 2 citations

Toxic reactions to meprobamate.

1957 • 1 citations

Changements survenus dans le sang à la suite du choc consécutif aux injections de colorants

1951 • 1 citations

[Research on the so-called degranulation of mast cells caused by histamine liberators].

1961 • 1 citations

Untersuchungen an Ionenaustauschmodellen zum Verständnis der Physiologie biogener Amine

1962 • 1 citations

Sur la Libération de L'Histamine Tissulaire, Provoquée Par L'Adrenochrome Et Ses Dérives

1957 • 1 citations

Über den Einfluß von Antistin auf Entstehung und Verlauf des durch Farbstoffe hervorgerufenen Schocks

1950 • 1 citations

Bronchospasm and antihistamine drugs.

1949 • 1 citations

[Estimation of the so-called histaminogenic effects of natural curares and of some synthetic curares].

1951 • 1 citations

Deleted Work

1955 • 0 citations