Double-stranded ribonucleic acid killer systems in yeasts

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

1977 • 5,640 citations

Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway

1980 • 1,808 citations

Codon selection in yeast.

1982 • 1,580 citations

Rapid Evolution of RNA Genomes

1982 • 1,475 citations

Possible role of flanking nucleotides in recognition of the AUG initiator codon by eukaryotic ribosomes

1981 • 1,265 citations

A putative signal peptidase recognition site and sequence in eukaryotic and prokaryotic signal peptides

1983 • 1,143 citations

Purification and Properties of an Endo-β-N-acetylglucosaminidase from Streptomyces griseus

1974 • 870 citations

Order of events in the yeast secretory pathway

1981 • 804 citations

Structure of a yeast pheromone gene (MFα): A putative α-factor precursor contains four tandem copies of mature α-factor

1982 • 587 citations

Secretion and cell-surface growth are blocked in a temperature-sensitive mutant of Saccharomyces cerevisiae

1979 • 518 citations

Glycosylation and processing of prepro-α-factor through the yeast secretory pathway

1984 • 410 citations

Yeast α factor is processed from a larger precursor polypeptide: The essential role of a membrane-bound dipeptidyl aminopeptidase

1983 • 403 citations

Expression of a human gene for interferon in yeast

1981 • 332 citations

Fatty acid binding to vesicular stomatitis virus glycoprotein: a new type of post-translational modification of the viral glycoprotein

1979 • 330 citations

Double-stranded RNA viruses

1983 • 322 citations

Compartmentalized assembly of oligosaccharides on exported glycoproteins in yeast

1981 • 302 citations

Studies on the Nature of the Killer Factor Produced by Saccharomyces cerevisiae

1968 • 281 citations

Isolation and characterization of linear deoxyribonucleic acid plasmids from Kluyveromyces lactis and the plasmid-associated killer character

1981 • 267 citations

Colicin K acts by forming voltage-dependent channels in phospholipid bilayer membranes

1978 • 263 citations

A comparison of the killer character in different yeasts and its classification

1978 • 262 citations

Sequence of the preprotoxin dsRNA gene of type I killer yeast: Multiple processing events produce a two-component toxin

1984 • 214 citations

Efficient cleavage and segregation of nascent presecretory proteins in a reticulocyte lysate supplemented with microsomal membranes.

1978 • 213 citations

Killer system: a simple method for differentiating Candida albicans strains

1983 • 209 citations

Preliminary Characterization of Two Species of dsRNA in Yeast and their Relationship to the “Killer” Character

1973 • 204 citations

Curing of a Killer Factor in Saccharomyces cerevisiae

1972 • 197 citations

The inheritance of the killer character in yeast

1969 • 196 citations

Electron microscopic heteroduplex analysis of "killer" double-stranded RNA species from yeast.

1978 • 186 citations

Isolation and Properties of Abrin: a Toxic Protein Inhibiting Protein Synthesis

1973 • 184 citations

Cell Wall Receptor for Yeast Killer Toxin: Involvement of (1 → 6)-β- <scp>d</scp> -Glucan

1983 • 180 citations

Viruses and Plasmids of Fungi

1980 • 166 citations

The occurrence of killer character in yeasts of various genera

1975 • 165 citations

Translation of the L-species dsRNA genome of the killer-associated virus-like particles of Saccharomyces cerevisiae.

1977 • 151 citations

Translational analysis of the killer-associated virus-like particle dsRNA genome of S. cerevisiae: M dsRNA encodes toxin

1980 • 148 citations

Superkiller mutations in Saccharomyces cerevisiae suppress exclusion of M2 double-stranded RNA by L-A-HN and confer cold sensitivity in the presence of M and L-A-HN.

1984 • 145 citations

Identification of Saccharomyces cerevisiae mutants deficient in DNA topoisomerase I activity.

1984 • 137 citations

Yeast Killer Mutants with Altered Double-Stranded Ribonucleic Acid

1974 • 136 citations

Physiology of Killer Factor in Yeast

1981 • 132 citations

Effect of yeast killer toxin on sensitive cells of Saccharomyces cerevisiae.

1981 • 132 citations

Virus-like Particles Associated with the Double-stranded RNA Species Found in Killer and Sensitive Strains of the Yeast Saccharomyces cerevisiae

1974 • 130 citations

TWO CHROMOSOMAL GENES REQUIRED FOR KILLING EXPRESSION IN KILLER STRAINS OF SACCHAROMYCES CEREVISIAE

1976 • 127 citations

Mode of action of yeast killer toxins: channel formation in lipid bilayer membranes

1983 • 123 citations

Yeast Killer Toxin: Purification and Characterisation of the Protein Toxin from Saccharomyces cerevisiae

1979 • 119 citations

“Killer Character” of Saccharomyces cerevisiae : Curing by Growth at Elevated Temperature

1974 • 117 citations

Yeast L dsRNA consists of at least three distinct RNAs; evidence that the non-mendelian genes [HOK], [NEX] and [EXL] are on one of these dsRNAs

1982 • 112 citations

Inheritance of killer phenotypes and double-stranded RNA in Ustilago maydis.

1976 • 104 citations

Chromosomal genes essential for replication of a double-stranded RNA plasmid of Saccharomyces cerevisiae: The killer character of yeast

1976 • 101 citations

A chromosomal gene required for killer plasmid expression, mating, and spore maturation in Saccharomyces cerevisiae.

1976 • 99 citations

The killer double-stranded RNA plasmids of yeast

1979 • 98 citations

The Reovirus Replicative Cycle

1976 • 98 citations

Identification and characterization of double-stranded RNA associated with cytoplasmic male sterility in Vicia faba

1981 • 97 citations

Killer-sensitive relationships in yeasts from natural habitats

1977 • 97 citations

CHROMOSOMAL AND NONCHROMOSOMAL MUTATIONS AFFECTING THE "KILLER CHARACTER" OF SACCHAROMYCES CEREVISIAE

1974 • 94 citations

VIRUSES OF EUCARYOTIC MICROORGANISMS

1976 • 93 citations

Binding of yeast killer toxin to a cell wall receptor on sensitive Saccharomyces cerevisiae

1979 • 92 citations

Killer DNA Plasmids of the Yeast Kluyveromyces lactis

1982 • 91 citations

Chromosomal mutants of Saccharomyces cerevisiae affecting the cell wall binding site for killer factor

1978 • 90 citations

Plasmids controlling exclusion of the K2 killer double-stranded RNA plasmid of yeast

1980 • 90 citations

Virus-Like Particles of Yeast

1980 • 89 citations

Viral pathogenesis and molecular biology

1977 • 87 citations

STRAINS OF YEAST LETHAL TO BREWERY YEASTS

1973 • 87 citations

Secretion ofSaccharomyces cerevisiaeKiller Toxin: Processing of the Glycosylated Precursor

1983 • 85 citations

Yeast viral RNA polymerase is a transcriptase

1980 • 81 citations

A glycosylated protoxin in killer yeast: Models for its structure and maturation

1983 • 80 citations

Mode of action of yeast toxins: energy requirement for Saccharomyces cerevisiae killer toxin

1977 • 80 citations

Transformation of Saccharomyces cerevisiae with linear DNA killer plasmids from Kluyveromyces lactis

1982 • 80 citations

Biochemical and physiological studies of the yeast virus-like particle

1977 • 80 citations

Cloning and sequencing of the preprotoxin-coding region of the yeast M1 double-stranded RNA.

1984 • 80 citations

Somatic segregation of the killer (k) and neutral (n) cytoplasmic genetic determinants in yeast

1969 • 79 citations

Replication of semliki forest virus: polyadenylate in plus-strand RNA and polyuridylate in minus-strand RNA

1976 • 79 citations

Nucleotide sequence of the putative recognition site for coat protein in the RN As of alfalfa mosaic virus and tobacco streak virus

1980 • 78 citations

Yeast killer factor: ATP leakage and coordinate inhibition of macromolecular synthesis in sensitive cells

1973 • 78 citations

Encapsidation of yeast killer double-stranded ribonucleic acids: dependence of M on L

1980 • 77 citations

Two New Double-Stranded RNA Molecules Showing Non-Mendelian Inheritance and Heat Inducibility in Saccharomyces cerevisiae

1984 • 75 citations

TWENTY-SIX CHROMOSOMAL GENES NEEDED TO MAINTAIN THE KILLER DOUBLE-STRANDED RNA PLASMID OF SACCHAROMYCES CEREVISIAE

1978 • 75 citations

YEAST DNA PLASMIDS

1983 • 75 citations

Preferential inclusion of extrachromosomal genetic elements in yeast meiotic spores.

1980 • 73 citations

Yeast killer plasmid mutations affecting toxin secretion and activity and toxin immunity function.

1982 • 73 citations

Specificity of Ustilago maydis Killer Proteins

1975 • 73 citations

Group Classification of Killer Yeasts Based on Cross-reactions between Strains of Different Species and Origin

1978 • 72 citations

Virion DNA-independent RNA polymerase from Saccharomyces cerevisiae

1980 • 71 citations

Yeast viral double-stranded RNAs have heterogeneous 3′ termini

1980 • 68 citations

"Superkiller" mutations suppress chromosomal mutations affecting double-stranded RNA killer plasmid replication in saccharomyces cerevisiae.

1980 • 66 citations

The 5' ends of yeast killer factor RNAs are pppGp

1976 • 66 citations

Ribosomal protein L3 is involved in replication or maintenance of the killer double-stranded RNA genome of Saccharomyces cerevisiae.

1982 • 65 citations

Killer of Saccharomyces cerevisiae: a double-stranded ribonucleic acid plasmid

1976 • 65 citations

Production, purification and properties of a Pichia kluyveri killer toxin

1979 • 63 citations

Curing of the killer deoxyribonucleic acid plasmids of Kluyveromyces lactis

1981 • 63 citations

Yeast virus-like particles possess a capsid-associated single-stranded RNA polymerase

1977 • 63 citations

Co-curing of plasmids affecting killer double-stranded RNAs of Saccharomyces cerevisiae: [HOK], [NEX], and the abundance of L are related and further evidence that M1 requires L

1982 • 62 citations

Transcription of killer virion double-stranded RNA in vitro

1980 • 60 citations

Transformation of Kluyveromyces lactis by killer plasmid DNA

1983 • 59 citations

A New Species of Double-stranded RNA from Yeast

1972 • 59 citations

A Nucleic Acid Associated with a Killer Strain of Yeast

1973 • 58 citations

Mak mutants of yeast: mapping and characterization

1979 • 57 citations

Purification and Characterization of Extracellular and Intracellular Killer Toxin of Saccharomyces cerevisiae Strain 28

1982 • 57 citations

Membrane-mediated killing of Saccharomyces cerevisiae by glycoproteins from Torulopsis glabrata

1975 • 57 citations

KILLER PHENOMENON IN USTILAGO MAYDIS: THE ORGANIZATION OF THE VIRAL GENOME

1978 • 56 citations

Saccharomyces cerevisiae killer virus transcripts contain template-coded polyadenylate tracts.

1984 • 56 citations

[HOK], A NEW YEAST NON-MENDELIAN TRAIT, ENABLES A REPLICATION-DEFECTIVE KILLER PLASMID TO BE MAINTAINED

1982 • 52 citations

Killer Phenomenon in Pathogenic Yeast

1979 • 49 citations

Killer Systems in Saccharomyces cerevisiae: Three Distinct Modes of Exclusion of M₂ Double-Stranded RNA by Three Species of Double-Stranded RNA, M₁, L-A-E, and L-A-HN

1983 • 49 citations

Killer phenomenon in Ustilago maydis: Mapping viral functions

1978 • 48 citations

Structural and functional analysis of separated strands of killer double-stranded RNA of yeast

1982 • 47 citations

Spermidine or spermine requirement for killer double-stranded RNA plasmid replication in yeast

1978 • 47 citations

Action of Yeast Killer Factor: a Resistant Mutant with Sensitive Spheroplasts

1973 • 47 citations

ISOLATION OF SUPPRESSIVE SENSITIVE MUTANTS FROM KILLER AND NEUTRAL STRAINS OF SACCHAROMYCES CEREVISIAE

1973 • 46 citations

Structure and function of the PHO82-pho4 locus controlling the synthesis of repressible acid phosphatase of Saccharomyces cerevisiae

1981 • 46 citations

A STUDY OF THE TRANSMISSION AND STRUCTURE OF DOUBLE STRANDED RNAs ASSOCIATED WITH THE KILLER PHENOMENON IN SACCHAROMYCES CEREVISIAE

1976 • 45 citations

pet 18: A chromosomal gene required for cell growth and for the maintenance of mitochondrial DNA and the killer plasmid of yeast

1978 • 44 citations

Multiple L Double-Stranded RNA Species of Saccharomyces cerevisiae: Evidence for Separate Encapsidation

1984 • 43 citations

Primary effects of yeast killer toxin

1980 • 43 citations

Killer Systems in Saccharomyces cerevisiae

1981 • 41 citations

VIRUS-LIKE PARTICLES IN USTILAGO MAYDIS: MUTANTS WITH PARTIAL GENOMES

1977 • 40 citations

There are at least two yeast viral double-stranded RNAs of the same size: An explanation for viral exclusion

1982 • 39 citations

Replication of double-stranded RNA of the virus-like particles in Saccharomyces cerevisiae

1981 • 39 citations

Separation and sequence of the 3′ termini of M double-stranded RNA from killer yeast

1982 • 38 citations

Genetic control of replication of the double-stranded RNA segments of the killer systems in Saccharomyces cerevisiae

1983 • 36 citations

Virus Particles in Yeast

1973 • 36 citations

Yeast killer dsRNA plasmids are transcribedin vivoto produce full and partial-length plus-stranded RNAs

1983 • 35 citations

TwoUstilago maydisviral dsRNAs of differentsizecode for the same product

1983 • 35 citations

DOMINANT CHROMOSOMAL MUTATION BYPASSING CHROMOSOMAL GENES NEEDED FOR KILLER RNA PLASMID REPLICATION IN YEAST

1977 • 35 citations

Sequences at the 3′ ends of yeast viral dsRNAs: proposed transcriptase and replicase initiation sites

1981 • 34 citations

Localization of genes for the double-stranded RNA killer virus of yeast.

1982 • 32 citations

The regulation of RNA synthesis in yeast IV

1979 • 32 citations

A MUTANT KILLER PLASMID WHOSE REPLICATION DEPENDS ON A CHROMOSOMAL "SUPERKILLER" MUTATION

1979 • 31 citations

Terminal adenylation in the synthesis of RNA by Q beta replicase.

1983 • 31 citations

High incidence of sensitivity to yeast killer toxins among Candida and Torulopsis isolates of human origin

1980 • 31 citations

Saccharomyces cerevisiae killer expression mutant kex2 has altered secretory proteins and glycoproteins

1979 • 31 citations

DELETION OF MITOCHONDRIAL DNA BYPASSING A CHROMOSOMAL GENE NEEDED FOR MAINTENANCE OF THE KILLER PLASMID OF YEAST

1977 • 30 citations

SUPPRESSION OF THE KILLER PHENOTYPE IN USTILAGO MAYDIS

1976 • 30 citations

MUTANTS OF THE KILLER PLASMID OF SACCHAROMYCES CEREVISIAE DEPENDENT ON CHROMOSOMAL DIPLOIDY FOR EXPRESSION AND MAINTENANCE

1976 • 28 citations

The genetic control of DS-RNA virus-like particles associated with Saccharomyces cerevisiae killer yeast

1976 • 28 citations

Defective Interference in the Killer System of Saccharomyces cerevisiae

1983 • 27 citations

Protein secretion in yeast: Two chromosomal mutants that oversecrete killer toxin in Saccharomyces cerevisiae

1983 • 27 citations

Evolution of defective-interfering double-stranded RNAs of the yeast killer virus

1979 • 27 citations

Virus-like particles and double stranded RNA from killer and non-killer strains of Saccharomyces cerevisiae.

1978 • 25 citations

Killer toxin for sake yeast: properties and effects of adenosine 5'-diphosphate and calcium ion on killing action

1977 • 25 citations

Killing of Torulopsis glabrata by Saccharomyces cerevisiae Killer Factor

1976 • 25 citations

Induction of yeast killer factor mutations

1977 • 25 citations

No homology between double-stranded RNA and nuclear DNA of yeast

1978 • 24 citations

Mapping the immunity function of the Ustilago maydis P1 virus

1982 • 23 citations

Killer DNA Plasmids of the Yeast Kluyveromyces lactis

1982 • 22 citations

Physiological conditions affecting the sensitivity of Saccharomyces cerevisiae to a Pichia kluyveri killer toxin and energy requirement for toxin action

1980 • 20 citations

Yeast dsRNA viral transcriptase pause products: identification of the transcript strand

1981 • 20 citations

The molecular biology of yeast killer factor

1976 • 20 citations

Specificity of polyamine requirements for the replication and maintenance of different double-stranded RNA plasmids in Saccharomyces cerevisiae.

1984 • 20 citations

Cloning of cDNA to a yeast viral double-stranded RNA and comparison of three viral RNAs

1982 • 18 citations

A new killer toxin produced by Saccharomyces cerevisiae

1982 • 18 citations

Evidence for a new chromosome in Saccharomyces cerevisiae.

1983 • 17 citations

Dual toxin specificities and the exclusion relations among the Ustilago dsRNA viruses

1982 • 17 citations

Properties of aCryptococcus laurentiikiller toxin and conditional killing effect of the toxin onCryptococcus albidus

1980 • 16 citations

Yeast L double-stranded ribonucleic acid is synthesized during the G1 phase but not the S phase of the cell cycle.

1981 • 15 citations

Synthesis of a double-stranded cDNA transcript of the killer toxin-coding region of the yeast M1 double-stranded RNA

1983 • 14 citations

Effects of potassium and sodium ions on the killing action of a Pichia kluyveri toxin in cells of Saccharomyces cerevisiae

1980 • 13 citations

PRECURSORS IN THE BIOSYNTHESIS OF INSULIN AND OTHER PEPTIDE HORMONES

1979 • 12 citations

Two biochemically and genetically different forms of L dsRNA of Saccharomyces cerevisiae exist: One form, L2, is correlated

1983 • 11 citations

Characterisation of the LdsRNA encoded mRNA of yeast

1981 • 10 citations

Reverse transcription of yeast double-stranded RNA and ribosomal RNA using synthetic oligonucleotide primers

1983 • 9 citations

Isolation and characterization of temperature-sensitive mak mutants of Saccharomyces cerevisiae

1980 • 8 citations

Selective inhibition of yeast killer-specific double-stranded RNA transcription invitro

1982 • 4 citations

["Killer" plasmid mutants obtained by exposure to 5-fluorouracil].

1981 • 4 citations