A mutant baculovirus with a temperature-sensitive IE-1 transregulatory protein

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A Film Detection Method for Tritium‐Labelled Proteins and Nucleic Acids in Polyacrylamide Gels

1974 • 8,693 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

1989 • 3,067 citations

The establishment of two cell lines from the insectspodoptera frugiperda (lepidoptera; noctuidae)

1977 • 1,219 citations

Prevention of Apoptosis by a Baculovirus Gene During Infection of Insect Cells

1991 • 810 citations

Isolation of genotypic variants of Autographa californica nuclear polyhedrosis virus

1978 • 313 citations

Apoptosis reduces both the in vitro replication and the in vivo infectivity of a baculovirus

1993 • 284 citations

Functional mapping of a trans-activating gene required for expression of a baculovirus delayed-early gene

1986 • 284 citations

Interspersed Homologous DNA of Autographa californica Nuclear Polyhedrosis Virus Enhances Delayed-Early Gene Expression

1986 • 214 citations

The Autographa californica Baculovirus Genome: Evidence for Multiple Replication Origins

1992 • 187 citations

Nucleotide Sequence and Temporal Expression of a Baculovirus Regulatory Gene

1987 • 187 citations

Identification, sequence, and transcriptional mapping of the major capsid protein gene of the baculovirus Autographa californica nuclear polyhedrosis virus

1989 • 184 citations

Identification and characterization of lef-1, a baculovirus gene involved in late and very late gene expression

1993 • 176 citations

Multiple early transcripts and splicing of the Autographa californica nuclear polyhedrosis virus IE-1 gene

1988 • 174 citations

Complete Sequence and Enhancer Function of the Homologous DNA Regions of Autographa californica Nuclear Polyhedrosis Virus

1986 • 172 citations

Eight base pairs encompassing the transcriptional start point are the major determinant for baculovirus polyhedrin gene expression

1988 • 170 citations

Molecular analysis of the transcriptional regulatory region of an early baculovirus gene

1989 • 152 citations

Location of Homologous DNA Sequences Interspersed at Five Regions in the Baculovirus AcMNPV Genome

1983 • 143 citations

Three baculovirus genes involved in late and very late gene expression: ie-1, ie-n, and lef-2

1993 • 141 citations

Divergent transcription of early 35- and 94-kilodalton protein genes encoded by the HindIII K genome fragment of the baculovirus Autographa californica nuclear polyhedrosis virus

1987 • 138 citations

Functional mapping of an AcNPV immediately early gene which augments expression of the IE-1 trans-activated 39K gene

1988 • 125 citations

Promoter influence on baculovirus-mediated gene expression in permissive and nonpermissive insect cell lines

1992 • 118 citations

Molecular analysis of the trans-activating IE-2 gene of Orgyia pseudotsugata multicapsid nuclear polyhedrosis virus

1992 • 116 citations

Characterization of an early gene accelerating expression of late genes of the baculovirus Autographa californica nuclear polyhedrosis virus

1988 • 116 citations

Baculovirus transcription in the presence of inhibitors and in nonpermissive Drosophila cells

1986 • 113 citations

Identification and characterization of the ie-1 gene of orgyia pseudotsugata multicapsid nuclear polyhedrosis virus

1991 • 110 citations

Molecular analysis of a baculovirus regulatory gene

1991 • 109 citations

Novel regulatory properties of the IE1 and IE0 transactivators encoded by the baculovirus Autographa californica multicapsid nuclear polyhedrosis virus

1991 • 106 citations

Identification of the very early transcribed baculovirus gene PE-38

1991 • 104 citations

Functional dissection of the Autographa californica nuclear polyhedrosis virus immediate-early 1 transcriptional regulatory protein

1992 • 89 citations

Transient expression of the Autographa californica nuclear polyhedrosis virus immediate-early gene, IE-N, is regulated by three viral elements

1991 • 89 citations

Location of Two Putative Origins of DNA Replication of Autographa californica Nuclear Polyhedrosis Virus

1993 • 81 citations

Expression of an enhancer-binding protein in insect cells transfected with the Autographa californica nuclear polyhedrosis virus IE1 gene

1991 • 80 citations

Differential gene expression mediated by late, very late and hybrid baculovirus promoters

1990 • 77 citations

Isolation, Complementation, and Initial Characterization of Temperature-Sensitive Mutants of the Baculovirus Autographa californica Nuclear Polyhedrosis Virus

1979 • 72 citations

Functional mapping of Autographa california nuclear polyhedrosis virus genes required for late gene expression

1988 • 66 citations

Identification, sequence, and transcriptional mapping of lef-3, a baculovirus gene involved in late and very late gene expression

1993 • 65 citations

Identification of spliced baculovirus RNAs expressed late in infection

1991 • 57 citations

A temperature-sensitive mutant of the baculovirus Autographa californica Nuclear polyhedrosis virus defective in an early function required for further gene expression

1983 • 49 citations

Nucleotide sequence of a transactivating Bombyx mori nuclear polyhedrosis virus immediate early gene

1992 • 31 citations

Construction of a Genetic Map of the Baculovirus Autographa californica Nuclear Polyhedrosis Virus by Marker Rescue of Temperature-Sensitive Mutants

1981 • 31 citations