In vivo topological analysis of Ste2, a yeast plasma membrane protein, by using beta-lactamase gene fusions.

Personal communication

1989 • 3,268 citations

In Vivo Half-Life of a Protein Is a Function of Its Amino-Terminal Residue

1986 • 1,942 citations

Yeast/E. coli shuttle vectors with multiple unique restriction sites

1986 • 1,399 citations

The spontaneous insertion of proteins into and across membranes: The helical hairpin hypothesis

1981 • 868 citations

Yeast plasma membrane ATPase is essential for growth and has homology with (Na+ + K+), K+- and Ca2+-ATPases

1986 • 801 citations

Control of Protein Exit from the Endoplasmic Reticulum

1989 • 794 citations

Methods in yeast genetics, laboratory manual

1987 • 733 citations

Isolation of the putative structural gene for the lysine-arginine-cleaving endopeptidase required for processing of yeast prepro-α-factor

1984 • 698 citations

KAR2, a karyogamy gene, is the yeast homolog of the mammalian BiP/GRP78 gene

1989 • 684 citations

A Genetic Approach to Analyzing Membrane Protein Topology

1986 • 610 citations

Control of topology and mode of assembly of a polytopic membrane protein by positively charged residues

1989 • 587 citations

Ubiquitin-mediated protein degradation.

1988 • 453 citations

Enzymes Required for Yeast Prohormone Processing

1988 • 446 citations

Nucleotide sequences of STE2 and STE3 , cell type-specific sterile genes from Saccharomyces cerevisiae

1985 • 351 citations

The yeast α-factor receptor: structural properties deduced from the sequence of theSTE2gene

1985 • 318 citations

The carboxy-terminal segment of the yeast α-factor receptor is a regulatory domain

1988 • 317 citations

TRK1 encodes a plasma membrane protein required for high-affinity potassium transport in Saccharomyces cerevisiae.

1988 • 291 citations

Yeast KEX2 gene encodes an endopeptidase homologous to subtilisin-like serine proteases

1988 • 236 citations

A Peptide Sequence Confers Retention and Rapid Degradation in the Endoplasmic Reticulum

1990 • 219 citations

Sequence of the preprotoxin dsRNA gene of type I killer yeast: Multiple processing events produce a two-component toxin

1984 • 214 citations

The C-terminus of the S. cerevisiae α-pheromone receptor mediates an adaptive response to pheromone

1988 • 214 citations

Bovine opsin has more than one signal sequence

1985 • 186 citations

Genetic analysis of the membrane insertion and topology of MalF, a cytoplasmic membrane protein of Escherichia coli

1988 • 175 citations

Analysis of protein localization by use of gene fusions with complementary properties

1990 • 147 citations

Intracellular degradation of unassembled asialoglycoprotein receptor subunits: a pre-Golgi, nonlysosomal endoproteolytic cleavage.

1989 • 146 citations

A vector for the construction of translational fusions to TEM β-lactamase and the analysis of protein export signals and membrane protein topology

1986 • 146 citations

A novel aspartyl protease allowing KEX2‐independent MFα propheromone processing in yeast

1990 • 135 citations

Positively charged amino acid residues can act as topogenic determinants in membrane proteins.

1989 • 122 citations

Multiple topogenic sequences in bovine opsin.

1987 • 115 citations

Effects of expression of mammalian G alpha and hybrid mammalian-yeast G alpha proteins on the yeast pheromone response signal transduction pathway.

1990 • 108 citations

Nucleotide sequence of the Saccharomyces cerevisiae PUT4 proline-permease-encoding gene: similarities between CAN1, HIP1 and PUT4 permeases

1989 • 106 citations

Negative control of DNA replication in composite SV40-bovine papilloma virus plasmids

1986 • 99 citations

Dual functions of the signal peptide in protein transfer across the membrane

1985 • 90 citations

The maltose permease encoded by the MAL61 gene of Saccharomyces cerevisiae exhibits both sequence and structural homology to other sugar transporters.

1989 • 74 citations

Genetic and biochemical evaluation of eucaryotic membrane protein topology: multiple transmembrane domains of Saccharomyces cerevisiae 3-hydroxy-3-methylglutaryl coenzyme A reductase.

1990 • 71 citations

Control Of Protein Exit From The Endoplasmic Reticulum

1989 • 35 citations

Response of Yeast Cells to a-Factor Pheromone: Topology of the Receptor and Identification of a Component of the Response Pathway

1988 • 25 citations

Enzymes Required For Yeast Prohormone Processing

1988 • 25 citations

Salvage receptors: Two of a kind?

1990 • 25 citations

The use of gene-fusions to determine membrane protein topology in Saccharomyces cerevisiae

1989 • 22 citations

Topology of membrane insertion in vitro and plasma membrane assembly in vivo of the yeast arginine permease

1988 • 19 citations