RNA secondary structure is an integral part of the in vitro mechanism of attenuation in simian virus 40

Improved Estimation of Secondary Structure in Ribonucleic Acids

1973 • 2,302 citations

Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product

1987 • 902 citations

A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells

1986 • 834 citations

Extensive homology among the largest subunits of eukaryotic and prokaryotic RNA polymerases

1985 • 670 citations

Prokaryotic and eukaryotic RNA polymerases have homologous core subunits.

1987 • 355 citations

Intragenic pausing and anti-sense transcription within the murine c-myc locus.

1986 • 326 citations

Separation and partial characterization of three functional steps in transcription initiation by human RNA polymerase II.

1985 • 311 citations

[35] In Vitro transcription: Whole-cell extract

1983 • 311 citations

DNA-RNA hybrid duplexes containing oligo(dA:rU) sequences are exceptionally unstable and may facilitate termination of transcription

1980 • 299 citations

Differential Expression of c- myb mRNA in Murine B Lymphomas by a Block to Transcription Elongation

1987 • 279 citations

Transcriptional arrest within the first exon is a fast control mechanism in c-myc gene expression

1986 • 254 citations

The C-terminal domain of the largest subunit of RNA polymerase II of Saccharomyces cerevisiae, Drosophila melanogaster, and mammals: a conserved structure with an essential function.

1988 • 246 citations

Sequence requirements for premature termination of transcription in the human c-myc gene

1988 • 246 citations

Mutations in the First Exon Are Associated with Altered Transcription of c- myc in Burkitt Lymphoma

1987 • 228 citations

Regulation of c-fosgene expression in hamster fibroblasts: initiation and elongation of transcription and mRNA degradation

1987 • 218 citations

Attenuation in the control of SV40 gene expression

1982 • 217 citations

Homology between RNA polymerases of poxviruses, prokaryotes, and eukaryotes: nucleotide sequence and transcriptional analysis of vaccinia virus genes encoding 147-kDa and 22-kDa subunits.

1986 • 178 citations

Identification of the SV40 agnogene product: a DNA binding protein

1981 • 170 citations

Rho-independent termination: dyad symmetry in DNA causes RNA polymerase to pause during transcription in vitro

1981 • 161 citations

Structure of the eukaryotic transcription apparatus: Features of the gene for the largest subunit of Drosophila RNA polymerase II

1985 • 140 citations

Pausing and premature termination of human RNA polymerase II during transcription of adenovirus in vivo and in vitro.

1984 • 114 citations

Pausing of RNA polymerase during in vitro transcription of the tryptophan operon leader region

1981 • 109 citations

Sarkosyl activation of RNA polymerase activity in mitotic mouse cells

1974 • 108 citations

Organization and Transcription of the Simian Virus 40 Genome

1979 • 77 citations

Molecular cloning and characterization of cDNA for eukaryotic transcription factor S-II.

1988 • 76 citations

Transcription of minute virus of mice, an autonomous parvovirus, may be regulated by attenuation

1984 • 75 citations

RNA polymerase II is capable of pausing and prematurely terminating transcription at a precise location in vivo and in vitro.

1989 • 69 citations

Mutations of the beta subunit of RNA polymerase alter both transcription pausing and transcription termination in the trp operon leader region in vitro.

1983 • 65 citations

Premature termination by human RNA polymerase II occurs temporally in the adenovirus major late transcriptional unit.

1984 • 61 citations

Attenuation in SV40 as a mechanism of transcription-termination by RNA polymerase B

1984 • 48 citations

Transcription analyses with heteroduplex trp attenuator templates indicate that the transcript stem and loop structure serves as the termination signal.

1983 • 44 citations

A direct analysis of transcribed minichromosomes: all transcribed SV40 minichromosomes have a nuclease-hypersensitive region within a nucleosome-free domain.

1984 • 43 citations

A block of transcription elongation by RNA polymerase II at synthetic sites in vitro

1989 • 37 citations

In vitro premature termination in SV40 late transcription.

1983 • 35 citations

Pausing of RNA polymerase molecules during in vivo transcription of the SV40 leader region.

1983 • 32 citations

Transcription termination in animal viruses and cells

1988 • 28 citations

Human RNA polymerase II can prematurely terminate transcription of the adenovirus type 2 late transcription unit at a precise site that resembles a prokaryotic termination signal

1987 • 26 citations

RNA is covalently linked to SV40 large T antigen.

1988 • 15 citations