Peripheral effects of insulin dominate suppression of fasting hepatic glucose production

Coated Charcoal Immunoassay of Insulin

1965 • 3,018 citations

DETERMINATION OF BLOOD SUGAR

1945 • 1,816 citations

Assessment of Insulin Sensitivityin Vivo*

1985 • 1,076 citations

Studies of pancreatic alpha cell function in normal and diabetic subjects

1970 • 825 citations

Equivalence of the insulin sensitivity index in man derived by the minimal model method and the euglycemic glucose clamp.

1987 • 771 citations

Estimation of Endogenous Glucose Production During Hyperinsulinemic-Euglycemic Glucose Clamps: Comparison of Unlabeled and Labeled Exogenous Glucose Infusates

1987 • 548 citations

The Control of Glycogen Metabolism in the Liver

1976 • 438 citations

Lilly Lecture 1980: Insulin Resistance and Insulin Action: An In Vitro and In Vivo Perspective

1981 • 317 citations

Insulin transport across capillaries is rate limiting for insulin action in dogs.

1989 • 299 citations

Influence of hyperinsulinemia, hyperglycemia, and the route of glucose administration on splanchnic glucose exchange

1978 • 293 citations

Influence of Endogenous Insulin Secretion on Splanchnic Glucose and Amino Acid Metabolism in Man

1971 • 270 citations

Portal and Peripheral Vein Immunoreactive Insulin Concentrations Before and After Glucose Infusion

1970 • 245 citations

Glucoregulatory responses in normal and diabetic dogs recorded by a new tracer method

1971 • 244 citations

In vivo kinetics of insulin action on peripheral glucose disposal and hepatic glucose output in normal and obese subjects.

1986 • 201 citations

Modeling Error and Apparent Isotope Discrimination Confound Estimation of Endogenous Glucose Production During Euglycemic Glucose Clamps

1988 • 157 citations

Differential Sensitivity of Glycogenolysis and Gluconeogenesis to Insulin Infusions in Dogs

1976 • 120 citations

Inhibition by insulin of hepatic glucose production in the normal dog

1965 • 110 citations

Role of Insulin in the Hepatic Handling of Glucose

1969 • 106 citations

A portal‐arterial glucose concentration gradient as a signal for an insulin‐dependent net glucose uptake in perfused rat liver

1986 • 94 citations

Direct and Indirect Effects of Insulin to Inhibit Hepatic Glucose Output in Obese Subjects

1987 • 86 citations

Underestimation of Glucose Turnover Measured With [6-3H]- and [6,6-2 H2]- but not [6-14C]glucose During Hyperinsulinemia in Humans

1989 • 79 citations

Interaction of insulin and glucose in the control of hepatic glucose balance

1974 • 74 citations

Reduction in Portal Vein Blood Flow by Somatostatin

1979 • 72 citations

THE PHYSIOLOGIC SIGNIFICANCE OF THE SECRETION OF ENDOGENOUS INSULIN INTO THE PORTAL CIRCULATION. I. COMPARISON OF THE EFFECTS OF GLUCAGON-FREE INSULIN ADMINISTERED VIA THE PORTAL VEIN AND VIA A PERIPHERAL VEIN ON THE MAGNITUDE OF HYPOGLYCEMIA AND PERIPHERAL GLUCOSE UTILIZATION1

1958 • 65 citations

Demonstration of the insulin receptor in vivo in rabbits and its possible role as a reservoir for the plasma hormone.

1978 • 62 citations

Effects of insulin at two dose levels on gluconeogenesis from alanine in fasting man

1980 • 57 citations

Effects of insulin on liver glycogen synthesis and breakdown in the dog

1965 • 51 citations

Effects of Portal and Peripheral Venous Insulin Infusion on Glucose Production and Utilization in Depancreatized, Conscious Dogs

1984 • 40 citations

Pattern of Postprandial Carbohydrate Metabolism and Effects of Portal and Peripheral Insulin Delivery

1990 • 36 citations

Comparison of portal and peripheral insulin delivery on carbohydrate metabolism in streptozotocin-diabetic rats

1985 • 34 citations

PACBERG: An adaptive program for controlling the blood sugar

1983 • 33 citations

EFFECTS OF EXOGENOUS AND ENDOGENOUS INSULIN ON GLUCOSE UTILIZATION AND PRODUCTION*

1959 • 29 citations

Comparison of the metabolic responses to portal and peripheral infusions of insulin in diabetic dogs

1981 • 27 citations

INSULIN INFUSION INTO THE PORTAL AND PERIPHERAL CIRCULATIONS OF UNANAESTHETIZED DOGS

1978 • 22 citations

The physiologic significance of portal vs. peripheral injection of insulin in man

1975 • 12 citations

Comparison of Portal and Peripheral Insulin Delivery on Lipid Metabolism in Streptozocin-diabetic Rats

1985 • 10 citations

Hepatic Glycogen Metabolism and Insulin Receptor Status After Long-term Peripheral Insulin Delivery in the Islet-Transplanted Diabetic Rat

1986 • 5 citations