Antitumor activity of a C-raf antisense oligonucleotide in combination with standard chemotherapeutic agents against various human tumors transplanted subcutaneously into nude mice.

Current concepts in antisense drug design

1993 • 566 citations

Antisense oligonucleotides inhibit intercellular adhesion molecule 1 expression by two distinct mechanisms.

1991 • 468 citations

Progress in Antisense Oligonucleotide Therapeutics

1996 • 317 citations

Combinatorially selected guanosine-quartet structureis a potent inhibitor of human immunodeficiency virus envelope-mediated cellfusion.

1994 • 297 citations

Therapeutic Applications Of Oligonucleotides

1992 • 158 citations

The complete coding sequence of the human A-raf-1 oncogene and transforming activity of a human A-rafcarrying retrovirus

1987 • 145 citations

Effects of Sequence of Thioated Oligonucleotides on Cultured Human Mammary Epithelial Cells

1993 • 137 citations

Potentiation of Apoptosis by Treatment With the Protein Kinase C-Specific Inhibitor Safingol in Mitomycin C-Treated Gastric Cancer Cells

1995 • 112 citations

Complete coding sequence of a human B-raf cDNA and detection of B-raf protein kinase with isozyme specific antibodies.

1990 • 112 citations

The Raf-1 serine/threonine protein kinase.

1994 • 67 citations

Antisense BCR-ABL oligomers cause non-specific inhibition of chronic myeloid leukemia cell lines.

1994 • 57 citations

Progress in antisense therapeutics

1996 • 37 citations

Inhibiting intracellular signalling as a strategy for cancer chemoprevention

1994 • 20 citations

Oligonucleotides protect cells from the cytotoxicity of several anti-cancer chemotherapeutic drugs.

1994 • 11 citations