The Binding of 2-(4′-Methylaminophenyl)Benzothiazole to Postmortem Brain Homogenates Is Dominated by the Amyloid Component

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD)

1991 • 4,669 citations

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1991 • 4,533 citations

Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB)

1996 • 3,940 citations

Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse

1999 • 3,112 citations

Amyloid deposition as the central event in the aetiology of Alzheimer's disease

1991 • 2,375 citations

Thioflavine T interaction with synthetic Alzheimer's disease β‐amyloid peptides: Detection of amyloid aggregation in solution

1993 • 2,137 citations

Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

2000 • 1,954 citations

A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N–terminus of β–amyloid

1992 • 1,453 citations

Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease

2001 • 1,264 citations

Evidence for Possible Involvement of 5-HT _2B Receptors in the Cardiac Valvulopathy Associated With Fenfluramine and Other Serotonergic Medications

2000 • 668 citations

X-ray diffraction from intraneuronal paired helical filaments and extraneuronal amyloid fibers in Alzheimer disease indicates cross-beta conformation.

1986 • 553 citations

Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain

2001 • 446 citations

A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain

2002 • 349 citations

Diffuse senile plaques occur commonly in the cerebellum in Alzheimer's disease.

1989 • 336 citations

Genetic dissection of Alzheimer's disease and related dementias: amyloid and its relationship to tau

1998 • 336 citations

Biochemical detection of Aβ isoforms: implications for pathogenesis, diagnosis, and treatment of Alzheimer’s disease

2000 • 282 citations

X-34, A Fluorescent Derivative of Congo Red: A Novel Histochemical Stain for Alzheimer's Disease Pathology

2000 • 270 citations

Motor Neurone Disease-inclusion Dementia

1996 • 224 citations

Research evaluation and diagnosis of possible Alzheimer’s disease over the last two decades: II

2000 • 185 citations

Development of small molecule probes for the Beta-amyloid protein of Alzheimer's Disease

1994 • 171 citations

Tau mutations in frontotemporal dementia FTDP-17 and their relevance for Alzheimer’s disease

2000 • 155 citations

Research evaluation and diagnosis of probable Alzheimer’s disease over the last two decades: I

2000 • 145 citations

Diffuse type of senile plaques in the cerebellum of Alzheimer-type dementia demonstrated by? protein immunostain

1989 • 139 citations

Biological Markers of Alzheimer’s Disease

1998 • 80 citations

Dementia of Frontal Type and Dementias with Subcortical Gliosis

1998 • 77 citations

An ‘anatomical cascade hypothesis’ for Alzheimer's disease

1992 • 77 citations

Atypical amyloid (Aβ) deposition in the cerebellum in Alzheimer's disease: an immunohistochemical study using end-specific Aβ monoclonal antibodies

1996 • 31 citations

Progress towards testing the amyloid hypothesis: inhibitors of APP processing.

2001 • 20 citations

The in vitro pharmacology of the β-adrenergic receptor pet ligand ( s )-fluorocarazolol reveals high affinity for cloned β-adrenergic receptors and moderate affinity for the human 5-HT 1A receptor

2001 • 12 citations