A nucleosome-positioning sequence is required for GCN4 to activate transcription in the absence of a TATA element.

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region

1985 • 1,244 citations

Five intermediate complexes in transcription initiation by RNA polymerase II

1989 • 1,033 citations

Sequences That Regulate the Divergent GAL1-GAL10 Promoter in Saccharomyces cerevisiae

1984 • 955 citations

Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of Yeast

1986 • 946 citations

Deletion analysis of GAL4 defines two transcriptional activating segments

1987 • 898 citations

Specific DNA binding of GAL4, a positive regulatory protein of yeast

1985 • 767 citations

The gradient morphogen bicoid is a concentration-dependent transcriptional activator

1989 • 655 citations

GAL4 activates transcription in Drosophila

1988 • 521 citations

Transcription factor ATF interacts with the TATA factor to facilitate establishment of a preinitiation complex

1988 • 488 citations

Factors involved in specific transcription by mammalian RNA polymerase II: purification, genetic specificity, and TATA box-promoter interactions of TFIID.

1988 • 477 citations

Promoters, activator proteins, and the mechanism of transcriptional initiation in yeast

1987 • 476 citations

Evidence for translational regulation of the activator of general amino acid control in yeast.

1984 • 472 citations

Function of a yeast TATA element-binding protein in a mammalian transcription system

1988 • 364 citations

The yeast UASG is a transcriptional enhancer in human hela cells in the presence of the GAL4 trans-activator

1988 • 362 citations

GAL4 activates gene expression in mammalian cells

1988 • 355 citations

Saturation Mutagenesis of the Yeast his3 Regulatory Site: Requirements for Transcriptional Induction and for Binding by GCN4 Activator Protein

1986 • 352 citations

Mammalian Glucocorticoid Receptor Derivatives Enhance Transcription in Yeast

1988 • 315 citations

Yeast TATA-binding protein TFIID binds to TATA elements with both consensus and nonconsensus DNA sequences.

1989 • 291 citations

Nucleotide sequence and transcriptional mapping of the yeastpet56-his3-dedlgene region

1985 • 290 citations

Yeast and human TATA-binding proteins have nearly identical DNA sequence requirements for transcription in vitro.

1990 • 281 citations

Statistical positioning of nucleosomes by specific protein-binding to an upstream activating sequence in yeast

1988 • 270 citations

5' untranslated sequences are required for the translational control of a yeast regulatory gene.

1984 • 257 citations

A yeast activity can substitute for the HeLa cell TATA box factor

1988 • 253 citations

Specific protein binding to far upstream activating sequences in polymerase II promoters.

1985 • 246 citations

Saturation mutagenesis of a yeast his3 "TATA element": genetic evidence for a specific TATA-binding protein.

1988 • 236 citations

Molecular mechanisms of transcriptional regulation in yeast

1990 • 224 citations

A wide variety of DNA sequences can functionally replace a yeast TATA element for transcriptional activation.

1990 • 212 citations

UASs and enhancers: Common mechanism of transcriptional activation in yeast and mammals

1988 • 187 citations

Factors Involved in Specific Transcription by Mammalian RNA Polymerase II: Purification, Genetic Specificity, and TATA Box-Promoter Interactions of TFIID

1988 • 184 citations

Constitutive and inducible Saccharomyces cerevisiae promoters: evidence for two distinct molecular mechanisms.

1986 • 181 citations

The JUN oncoprotein, a vertebrate transcription factor, activates transcription in yeast

1988 • 180 citations

Yeast activators stimulate plant gene expression

1988 • 167 citations

Cloning of random-sequence oligodeoxynucleotides

1986 • 162 citations

Accurate initiation at RNA polymerase II promoters in extracts from Saccharomyces cerevisiae.

1987 • 141 citations

Distinguishing between mechanisms of eukaryotic transcriptional activation with bacteriophage T7 RNA polymerase

1987 • 141 citations

Genetic properties and chromatin structure of the yeast gal regulatory element: an enhancer-like sequence.

1984 • 137 citations

Nucleotide sequence of Saccharomyces cerevisiae genes TRP2 and TRP3 encoding bifunctional anthranilate synthase: indole-3-glycerol phosphate synthase.

1984 • 127 citations

In vivo DNA-binding properties of a yeast transcription activator protein.

1987 • 112 citations

Functional distinctions between yeast TATA elements.

1989 • 111 citations

Yeast and Human TATA-Binding Proteins Have Nearly Identical DNA Sequence Requirements for Transcription In Vitro

1990 • 104 citations

Gene activation and DNA binding by Drosophila Ubx and abd-A proteins

1989 • 77 citations

Analysis of Saccharomyces cerevisiae his3 transcription in vitro: biochemical support for multiple mechanisms of transcription.

1990 • 70 citations

GAL1-GAL10 divergent promoter region of Saccharomyces cerevisiae contains negative control elements in addition to functionally separate and possibly overlapping upstream activating sequences.

1987 • 65 citations

Negative control at a distance mediates catabolite repression in yeast

1985 • 54 citations

The Drosophila fushi tarazu polypeptide is a DNA-binding transcriptional activator in yeast cells

1989 • 50 citations

Yeast upstream activator protein GCN4 can stimulate transcription when its binding site replaces the TATA element.

1989 • 47 citations

Yeast GCN4 transcriptional activator protein interacts with RNA polymerase II in vitro.

1989 • 41 citations

Functional Distinctions between Yeast TATA Elements

1989 • 37 citations

Structure and function of the TRP3 gene of Saccharomyces cerevisiae: Analysis of transcription, promoter sequence, and sequence coding for a glutamine amidotransferase

1984 • 36 citations

Molecular Mechanisms Of Transcriptional Regulation In Yeast

1989 • 22 citations

Differential repression of GAL4 and adjacent transcription activators by operators in the yeast GAL upstream activating sequence.

1989 • 17 citations