Pharmacokinetics and Tolerance of the Natural Pentasaccharide (SR90107/ORG31540) with High Affinity to Antithrombin III in Man

Structure-activity relationship in heparin: A synthetic pentasaccharide with high affinity for antithrombin III and eliciting high anti-factor Xa activity

1983 • 651 citations

Total synthesis of a heparin pentasaccharide fragment having high affinity for antithrombin III

1984 • 225 citations

STRUCTURAL STUDIES ON A BIOLOGICALLY ACTIVE HEXASACCHARIDE OBTAINED FROM HEPARIN

1981 • 225 citations

The Antithrombotic Activity and Pharmacokinetics of Enoxaparine, A Low Molecular Weight Heparin, In Humans Given Single Subcutaneous Doses of 20 to 80 mg

1988 • 169 citations

Synthesis of a Pentasaccharide Corresponding to the Antithrombin III Binding Fragment of Heparin

1985 • 160 citations

Delayed elimination of enoxaparine in patients with chronic renal insufficiency

1991 • 154 citations

Low molecular weight heparin (KABI 2165, Fragmin): pharmacokinetics after intravenous and subcutaneous administration in human volunteers

1986 • 119 citations

Antithrombotic activity of a synthetic heparin pentasaccharide in a rabbit stasis thrombosis model using different thrombogenic challenges

1987 • 93 citations

Pharmacokinetics of a Low Molecular Weight Heparin (Fraxiparine®) in Various Stages of Chronic Renal Failure

1991 • 74 citations

The Action of a Synthetic Pentasaccharide on Thrombin Generation in Whole Plasma

1989 • 60 citations

Unfractionated heparin and CY 216: pharmacokinetics and bioavailabilities of the antifactor Xa and IIa effects after intravenous and subcutaneous injection in the rabbit.

1989 • 54 citations

Intravenous antithrombotic activity of a synthetic heparin pentasaccharide in a human serum induced stasis thrombosis model

1986 • 50 citations

Pharmacological Profile of the Chemically Synthesized Antithrombin III Binding Fragment of Heparin (Pentasaccharide) in Rats

1990 • 48 citations

Antithrombotic Effects of Synthetic Pentasaccharide with High Affinity for Plasma Antithrombin III in Non-Human Primates

1993 • 44 citations

Pharmacokinetic and antithrombotic properties of two pentasaccharides with high affinity to antithrombin III in the rabbit: comparison with CY216

1994 • 37 citations

Antithrombotic potencies of heparins in relation to their antifactor Xa and antithrombin activities: an experimental study in two models of thrombosis in the rabbit

1990 • 36 citations

The Relative Antithrombotic Effectiveness of Heparin, a Low Molecular Weight Heparin, and a Pentasaccharide Fragment in an Animal Model

1989 • 36 citations

Comparative Inhibition of Extrinsic and Intrinsic Thrombin Generation by Standard Heparin, a Low Molecular Weight Heparin and the Synthetic ATIII-Binding Pentasaccharide

1993 • 27 citations

Pharmacokinetics of fragmin. A comparative study in the rabbit of its high and low affinity forms for antithrombin

1987 • 26 citations

Pentasaccharide and Orgaran® Arrest, whereas Heparin Delays Thrombus Formation in a Rat Arteriovenous Shunt

1993 • 26 citations

Heparin fractions with high and low affinities to antithrombin iii are cleared at different rates

1986 • 18 citations

Deleted Work

1955 • 0 citations