The medical management of reflux esophagitis. Role of antacids and acid inhibition.

Alzheimer's Disease: X-Ray Spectrometric Evidence of Aluminum Accumulation in Neurofibrillary Tangle-Bearing Neurons

1980 • 995 citations

Symptomatic gastroesophageal reflux: Incidence and precipitating factors

1976 • 895 citations

Healing and relapse of severe peptic esophagitis after treatment with omeprazole

1988 • 792 citations

Gastrointestinal Absorption of Aluminum from Aluminum-Containing Antacids

1977 • 398 citations

DOUBLE-BLIND MULTICENTRE COMPARISON OF OMEPRAZOLE AND RANITIDINE IN THE TREATMENT OF REFLUX OESOPHAGITIS

1987 • 282 citations

Omeprazole or Ranitidine in the Treatment of Reflux Esophagitis: Results of a Double-Blind, Randomized, Scandinavian Multicenter Study

1988 • 277 citations

Optimal dose of oral omeprazole for maximal 24 hour decrease of intragastric acidity.

1984 • 237 citations

Medical and Surgical Management of Reflux Esophagitis

1975 • 228 citations

Omeprazole and ranitidine in treatment of reflux oesophagitis: double blind comparative trial

1988 • 216 citations

Healing and Relapse of Reflux Esophagitis During Treatment With Ranitidine

1986 • 199 citations

Cimetidine in the treatment of symptomatic gastroesophageal reflux

1978 • 195 citations

Omeprazole (40 mg) is superior to ranitidine in short-term treatment of ulcerative reflux esophagitis

1988 • 185 citations

Oral cimetidine in reflux esophagitis: A double blind controlled trial

1978 • 169 citations

Comparison of the effects of ranitidine, cimetidine and placebo on the 24 hour intragastric acidity and nocturnal acid secretion in patients with duodenal ulcer.

1981 • 167 citations

Oesophagitis, Signs of Reflux, and Gastric Acid Secretion in Patients with Symptoms of Gastro-Oesophageal Reflux Disease

1986 • 165 citations

Malignant Hyper-Pyrexia and Sudden Infant Death

1982 • 165 citations

Omeprazole inhibits oxidative drug metabolism. Studies with diazepam and phenytoin in vivo and 7-ethoxycoumarin in vitro.

1985 • 162 citations

Omeprazole inhibits oxidative drug metabolism

1985 • 160 citations

GASTRIC AND DUODENAL ULCER

1915 • 158 citations

The hiatus hernia-esophagitis-esophageal stricture complex

1968 • 157 citations

Medical and surgical options in the management of patients with gastrinoma

1983 • 147 citations

Evidence of aluminum absorption from the gastrointestinal tract and bone deposition by aluminum carbonate ingestion with normal renal function.

1977 • 142 citations

Metabolic balance of aluminum studied in six men.

1979 • 141 citations

Reflux esophagitis in patients with Zollinger-Ellison syndrome

1990 • 140 citations

Blood Transfusion and Prognosis in Colorectal Carcinoma

1989 • 127 citations

Why do apparently healthy people use antacid tablets?

1983 • 121 citations

Characterization of cimetidine, ranitidine, and related structures' interaction with cytochrome P-450.

1983 • 119 citations

CIMETIDINE AND GASTRIC CANCER

1979 • 115 citations

Double-blind comparison of liquid antacid and placebo in the treatment of symptomatic reflux esophagitis

1983 • 110 citations

Gastric Alkalinization

1974 • 107 citations

Therapy with Omeprazole in Patients With Peptic Ulcerations Resistant to Extended High-Dose Ranitidine Treatment

1988 • 106 citations

Cimetidine, Metoclopramide, or Placebo in the Treatment of Symptomatic Gastroesophageal Reflux

1980 • 103 citations

Treatment of reflux oesophagitis with ranitidine.

1983 • 96 citations

Epidemiology of oesophageal reflux disease.

1989 • 95 citations

Oral phenytoin pharmacokinetics during omeprazole therapy.

1987 • 91 citations

Omepmazole or high‐dose ranitidine in the treatment of patients with reflux oesophagitis not responding to ‘standard doses’of H₂‐receptor antagonists

1990 • 90 citations

GOLD REVALUED

1974 • 90 citations

Acute treatment of reflux oesophagitis: a multicentre trial to compare 150 mg ranitidine b.d. with 300 mg ranitidine q.d.s.

1989 • 89 citations

Ranitidine Therapy for Gastroesophageal Reflux Disease

1987 • 88 citations

Controlled trial of cimetidine in reflux esophagitis

1980 • 85 citations

EFFECT OF CIMETIDINE IN SYMPTOMATIC GASTRO-ŒSOPHAGEAL REFLUX

1978 • 81 citations

Adverse Effects of Aluminum-Containing Antacids on Mineral Metabolism

1979 • 77 citations

Ranitidine and High-Dose Antacid in Reflux Oesophagitis

1985 • 66 citations

Famotidine: A Notable Lack of Drug Interactions

1987 • 64 citations

Aluminium hydroxide versus sucralfate as a phosphate binder in uraemia.

1983 • 58 citations

Cimetidine and gastric cancer: preliminary report from post-marketing surveillance study.

1982 • 57 citations

A Multicentric, Randomized Clinical Trial of Gaviscon in Reflux Esophagitis

1978 • 54 citations

Ranitidine in the treatment of symptomatic gastroesophageal reflux disease.

1984 • 54 citations

Omeprazole: effects on oxidative drug metabolism.

1984 • 53 citations

Propranolol steady-state pharmacokinetics are unaltered by omeprazole

1987 • 53 citations

[Omeprazole (20 mg daily) compared to ranitidine (150 mg twice daily) in the treatment of esophagitis caused by reflux. Results of a double-blind randomized multicenter trial in France and Belgium].

1989 • 52 citations

Double-Blind Crossover Study of Ranitidine and Placebo in Gastro-oesophageal Reflux Disease

1986 • 51 citations

Ranitidine in Reflux Oesophagitis

1984 • 51 citations

SYMPTOMATIC REFLUX ESOPHAGITIS: A DOUBLE-BLIND CONTROLLED COMPARISON OF ANTACIDS AND ALGINATE.

1977 • 49 citations

A Critical Review of Current Medical Therapy for Gastroesophageal Reflux Disease

1986 • 49 citations

Cimetidine in the treatment of Zollinger-Ellison syndrome

1983 • 45 citations

Assessing the safety of drugs for the long-term treatment of peptic ulcers.

1984 • 45 citations

Dose-response effect of famotidine on patterns of gastro-oesophageal reflux

1988 • 43 citations

Gastroesophageal Reflux Disease: Acute and Maintenance Treatments with Cimetidine

1986 • 42 citations

Ranitidine and placebo in the treatment of reflux oesophagitis: A double‐blind randomized trial

1983 • 42 citations

CIMETIDINE IN THE TREATMENT OF REFLUX OESOPHAGITIS

1979 • 39 citations

Use of Omeprazole in the Management of Reflux Oesophagitis Resistant to H₂-receptor Antagonists

1989 • 38 citations

Ranitidine vs metoclopramide in the medical treatment of reflux esophagitis.

1983 • 37 citations

The Effect of Omeprazole or Ranitidine Treatment on 24-Hour Esophageal Acidity in Patients with Reflux Esophagitis

1988 • 37 citations

Intensive Hospital Monitoring Study of Intravenous Cimetidine

1986 • 36 citations

Lack of Effect of Nizatidine on Drug Metabolism

1987 • 34 citations

Ranitidine, 150 mg Three Times a Day, in the Treatment of Reflux Oesophagitis: A Placebo-Controlled, Double-Blind Study

1986 • 30 citations

Bethanechol or Cimetidine in the Treatment of Symptomatic Reflux Esophagitis

1982 • 30 citations

Elevation of gastric pH heals peptic oesophagitis ‐ A role for omeprazole

1987 • 28 citations

Hepatotoxic and hepatoprotective potential of histamine (H2)-receptor antagonists

1987 • 27 citations

Omeprazole in the Long-term Management of Patients with Reflux Oesophagitis Refractory to Histamine H₂-receptor Antagonists

1989 • 27 citations

Comparison between ranitidine and cimetidine in the treatment of reflux oesophagitis.

1984 • 26 citations

The Hepatic and Renal Mechanisms of Drug Interactions with Cimetidine

1986 • 25 citations

Quantitation of Gastroesophageal Reflux Before and After Therapy Using the Gastroesophageal Scintiscan

1978 • 24 citations

Safety perspectives on parenteral H2-receptor antagonists

1987 • 24 citations

Summary of the 34th meeting of the Food and Drug Administration Gastrointestinal Drugs Advisory Committee. March 15 and 16, 1989 (omeprazole and domperidone).

1989 • 23 citations

Antacids for Peptic Ulcer: Do We Have Anything Better?

1986 • 20 citations

The Effects of Omeprazole on Gastro-oesophageal Sphincter Pressure, Intragastric pH, and the Migrating Motor Complex in Fasting Healthy Subjects

1987 • 17 citations

Anti-ulcer therapy

1985 • 15 citations

Diagnosis and Management of the Zollinger-Ellison Syndrome

1983 • 12 citations

Dose-ranging in clinical trials: rationale and proposed use with placebo or positive controls.

1986 • 12 citations

Cimetidine for the treatment of symptomatic gastro-oesophageal reflux.

1981 • 10 citations

Omeprazole in the Treatment of Erosive Oesophagitis Refractory to High-dose Cimetidine

1989 • 7 citations

Double-blind assessment of therapeutic efficacy in clinical trials

1983 • 5 citations

OMEPRAZOLE

1987 • 3 citations

Aluminium sucrose biscuit fillings to control hyperphosphataemia in patients undergoing dialysis.

1981 • 3 citations