Purification and cDNA Cloning of Human Liver CYP4A Fatty Acid ω-Hydroxylase

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 3,435 citations

Protein Purification by Affinity Chromatography

1970 • 2,809 citations

The P450 Superfamily: Update on New Sequences, Gene Mapping, Accession Numbers, Early Trivial Names of Enzymes, and Nomenclature

1993 • 1,663 citations

A Form of Cytochrome b ₅ That Contains an Additional Hydrophobic Sequence of 40 Amino Acid Residues

1971 • 453 citations

Purification and characterization of hepatic microsomal cytochrome P-450

1990 • 379 citations

Isolation, complementary DNA sequence, and regulation of rat hepatic lauric acid omega-hydroxylase (cytochrome P-450LA omega). Identification of a new cytochrome P-450 gene family.

1987 • 317 citations

20-Hydroxyeicosatetraenoic acid is an endogenous vasoconstrictor of canine renal arcuate arteries.

1993 • 250 citations

Characterization of Human Microsomal Cytochrome P-450 Enzymes

1989 • 244 citations

Interaction between NADPH-cytochrome p-450 reductase and cytochrome p-450 in the membrane of phosphatidylcholine vesicles

1979 • 159 citations

Human cytochrome P-450 enzymes

1992 • 157 citations

Structural Characteristics of Cytochrome P-450. Possible Location of the Heme-Binding Cysteine in Determined Amino-Acid Sequences

1983 • 146 citations

A novel form of cytochrome P-450 family 4 in human polymorphonuclear leukocytes. cDNA cloning and expression of leukotriene B4 omega-hydroxylase

1993 • 137 citations

Cytochrome P450 family 4 in a cockroach: molecular cloning and regulation by regulation by hypertrehalosemic hormone.

1991 • 124 citations

Multiple Forms of Cytochrome P-450 Purified from Liver Microsomes of Phenobarbital- and 3-Methylcholanthrene-Pretreated Rabbits

1980 • 123 citations

cDNA cloning and inducible expression during pregnancy of the mRNA for rabbit pulmonary prostaglandin omega-hydroxylase (cytochrome P-450p-2).

1987 • 92 citations

[56] Isolation of P450 enzymes from human liver

1991 • 90 citations

Expression of Bovine Cytochrome P450c21 and Its Fused Enzymes with Yeast NADPH-Cytochrome P450 Reductase inSaccharomyces cerevisiae

1990 • 86 citations

19(S)-hydroxyeicosatetraenoic acid is a potent stimulator of renal Na+-K+-ATPase

1988 • 84 citations

Characterization of a cDNA encoding a human kidney, cytochrome 4A fatty acid ω-hydroxylase and the cognate enzyme expressed in Escherichia coli

1993 • 75 citations

Isolation of Cytochrome P-450 Highly Active in Prostaglandin ω-Hydroxylation from Lung Microsomes of Rabbits Treated with Progesterone1

1984 • 62 citations

Two Forms of ω-Hydroxylase Toward Prostaglandin A and Laurate

1989 • 60 citations

Catalytic properties of rabbit kidney fatty acid omega-hydroxylase cytochrome P-450ka2 (CYP4A7).

1993 • 51 citations

Mutations at the distal and proximal sites of cytochrome P-450d changed regio-specificity of acetanilide hydroxylations

1989 • 42 citations

cDNA cloning and expression of the mRNA for cytochrome P‐450_kd which shows a fatty acid ω‐hydroxylating activity

1991 • 36 citations

cDNA cloning of cytochrome P‐450 related to P‐450_p‐2 from the cDNA library of human placenta

1990 • 33 citations

Purification and NH2-terminal amino acid sequences of human and rat kidney fatty acid ω-hydroxylases

1992 • 33 citations

Isolation of a New Form of Cytochrome P-450 with Prostaglandin A and Fatty Acid w-Hydroxylase Activities from Rabbit Kidney Cortex Microsomes1

1989 • 31 citations

Drug and fatty acid hydroxylation by solubilized human liver microsomal cytochrome P-450—Phospholipid requirement

1975 • 30 citations

Purification and Characterization of Two Forms of Cytochrome P-450 with ω-Hydroxylase Activities toward Prostaglandin A and Fatty Acids from Rabbit Liver Microsomes1

1990 • 24 citations

Purification and Characterization of Two Forms of Fatty Acid ω-Hydroxylase Cytochrome P-450 from Rabbit Kidney Cortex Microsomes1

1990 • 17 citations

Lauric acid hydroxylase activity and cytochrome P450 IV family proteins in human liver microsomes

1991 • 15 citations