LOH at the APC/MCC Gene (5Q21) in Gastric Cancer and Preneoplastic Lesions

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

1993 • 2,884 citations

Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer

1994 • 2,071 citations

Molecular themes in oncogenesis

1991 • 1,663 citations

Tumor suppressor genes

1991 • 775 citations

Genetic instability in pancreatic cancer and poorly differentiated type of gastric cancer.

1993 • 443 citations

Genetic alterations in the adenoma–carcinoma sequence

1992 • 381 citations

Phenotypic and genotypic events in gastric carcinogenesis.

1994 • 329 citations

LOSS OF CONSTITUTIONAL HETEROZYGOSITY IN HUMAN CANCER

1991 • 318 citations

A microdissection technique for archival DNA analysis of specific cell populations in lesions < 1 mm in size.

1995 • 267 citations

Somatic mutation of the APC gene in gastric cancer: frequent mutations in very well differentiated adenocarcinoma and signet-ring cell carcinoma

1992 • 229 citations

Microsatellite instability in the progression of gastric carcinoma.

1994 • 205 citations

p53 mutations and microsatellite instability in sporadic gastric cancer: when guardians fail.

1994 • 183 citations

Progressing toward a molecular description of colorectal cancer development

1992 • 148 citations

Allelic deletions of MCC/APC and p53 are frequent late events in human gastric carcinogenesis

1994 • 98 citations

Mutations of the APC gene occur during early stages of gastric adenoma development.

1994 • 89 citations

Molecular biology and gastric carcinoma.

1993 • 62 citations

Somatic mutations of the APC gene in precancerous lesion of the stomach

1993 • 61 citations

Abnormalities affecting the APC and MCC tumour suppressor gene loci on chromosome 5q occur frequently in gastric cancer but not in pancreatic cancer

1993 • 59 citations

Loss of heterozygosity and K-ras gene mutations in gastric cancer

1993 • 53 citations

CA repeat polymorphism at the D5S299 locus linked to adenomatous polyposis coli (APC)

1991 • 52 citations

Primary Gastric Carcinoma Cells Frequently Lose Heterozygosity at the APC and MCC Genetic Loci

1993 • 51 citations

Pathology of the Gastrointestinal Tract

1993 • 42 citations

Loss Of Constitutional Heterozygosity In Human Cancer

1991 • 18 citations

The tumour suppressor APC gene product is associated with cell adhesion

1994 • 14 citations

Lack of mutations of the adenomatous polyposis coli gene in oesophageal and gastric carcinomas

1994 • 14 citations