Acetate represents a major product of heptanoate and octanoate β-oxidation in hepatocytes isolated from neonatal piglets

Brain Metabolism during Fasting*

1967 • 1,590 citations

Production and utilization of acetate in mammals

1974 • 340 citations

The role of malonyl-coa in the coordination of fatty acid synthesis and oxidation in isolated rat hepatocytes.

1978 • 269 citations

Influence of valproic acid on hepatic carbohydrate and lipid metabolism

1983 • 159 citations

Origins of blood acetate in the rat

1977 • 130 citations

Valproylcarnitine: a novel drug metabolite identified by fast atom bombardment and thermospray liquid chromatography-mass spectrometry

1985 • 117 citations

The contribution of the large intestine to blood acetate in man

1991 • 105 citations

Relationship between unusual hepatic acyl coenzyme A profiles and the pathogenesis of Reye syndrome.

1988 • 86 citations

The enzymatic basis for the metabolism and inhibitory effects of valproic acid: dehydrogenation of valproyl-CoA by 2-methyl-branched-chain acyl-CoA dehydrogenase

1990 • 69 citations

Action of the antiepileptic drug, valproic acid, on fatty acid oxidation in isolated rat hepatocytes

1983 • 65 citations

Utilization of Medium-Chain Triglycerides by Neonatal Piglets: Chain Length of Even- and Odd-Carbon Fatty Acids and Apparent Digestion/Absorption and Hepatic Metabolism

1991 • 63 citations

Insulin and Ketone Responses to Ingestion of Medium and Long-chain Triglycerides in Man

1969 • 60 citations

A single therapeutic dose of valproate affects liver carbohydrate, fat, adenylate, amino acid, coenzyme A, and carnitine metabolism in infant mice: Possible clinical significance

1985 • 58 citations

Interactions in vivo between oxidation of non-esterified fatty acids and gluconeogenesis in the newborn rat

1979 • 57 citations

Metabolic fate of non-esterified fatty acids in isolated hepatocytes from newborn and young pigs. Evidence for a limited capacity for oxidation and increased capacity for esterification

1983 • 50 citations

Hepatic ketogenesis in newborn pigs is limited by low mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase activity

1994 • 48 citations

Skeletal muscle mitochondrial β-oxidation. A study of the products of oxidation of [U-14C]hexadecanoate by h.p.l.c. using continuous on-line radiochemical detection

1988 • 44 citations

Plasma Levels of FFA, Glycerol, β-Hydroxybutyrate and Blood Glucose during the Postnatal Development of the Pig

1969 • 41 citations

The relationship of plasma acetate with glucose and other blood intermediary metabolites in non-diabetic and diabetic subjects

1989 • 41 citations

Amelioration of Adverse Effects of Valproic Acid on Ketogenesis and Liver Coenzyme A Metabolism by Cotreatment with Pantothenate and Carnitine in Developing Mice: Possible Clinical Significance

1992 • 39 citations

Changes in circulating fuels, pancreatic hormones and liver glycogen concentration in fasting or suckling newborn pigs.

1981 • 38 citations

Carnitine palmitoyltransferase modulation of hepatic fatty acid metabolism and radio-HPLC evidence for low ketogenesis in neonatal pigs.

1995 • 38 citations

Changes in Hepatic Fatty Acid Degradation and Blood Lipid and Ketone Body Content during Development of the Rat

1976 • 37 citations

Hepatic triglyceride hydrolysis and development of ketogenesis in rabbits

1985 • 37 citations

Diabetic Ketoacidosis: Biochemistry, Physiology, Treatment, and Prevention

1987 • 34 citations

A comparison of the utilization of medium and long-chain fatty acids for oxidation and ketogenesis in the suckling rat: In vivo and in vitro studies

1981 • 33 citations

Utilization of Medium-Chain Triglycerides by Neonatal Piglets: II. Effects of Even- and Odd-Chain Triglyceride Consumption over the First 2 Days of Life on Blood Metabolites and Urinary Nitrogen Excretion

1989 • 33 citations

Carnitine affects octanoate oxidation to carbon dioxide and dicarboxylic acids in colostrum-deprived piglets: in vivo analysis of mechanisms involved based on CoA- and carnitine-ester profiles.

1995 • 26 citations

Xanthine oxidase for calibration of the oxygen electrode apparatus

1970 • 25 citations

Postnatal Age and the Metabolism of Medium- and Long-Chain Fatty Acids by Isolated Hepatocytes from Small-for-Gestational-Age and Appropriate-for-Gestational-Age Piglets

1991 • 25 citations

Products and intermediates of the β-oxidation of [U-14C]hexadecanedionoyl-mono-CoA by rat liver peroxisomes and mitochondria

1991 • 21 citations

Plasma beta-hydroxybutyrate after octanoate challenge: attenuated ketogenic capacity in neonatal swine

1993 • 20 citations

Relationship between hepatic fatty acid oxidation and gluconeogenesis in the fasting neonatal pig

1993 • 14 citations

Octanoate metabolism in isolated hepatocytes and mitochondria from fetal, newborn and adult rabbit

1989 • 11 citations

Metabolic effects following a medium chain triglycerides load in dogs: V. — Influence of the perfusion rate

1974 • 9 citations

Effect of intragastric triglyceride administration on glucose homeostasis in newborn pigs

1985 • 9 citations

Fuel metabolism and energy stores in fasting or suckling newborn guinea pigs.

1983 • 4 citations