Genetics of Alcoholism

Evidence of Genetic Predisposition to Alcoholic Cirrhosis and Psychosis: Twin Concordances for Alcoholism and Its Biological End Points by Zygosity among Male Veterans

1981 • 459 citations

Differences in Alcohol Preference among Inbred Strains of Mice

1959 • 453 citations

Genetic Selection for Voluntary Alcohol Consumption in the Albino Rat

1968 • 450 citations

Genetic Animal Models of Alcohol and Drug Abuse

1994 • 435 citations

Selective breeding for alcohol preference and associated responses

1993 • 325 citations

Alcoholism and Heredity

1979 • 319 citations

Localization of Genes Affecting Alcohol Drinking in Mice

1994 • 298 citations

Quantitative Trait Loci Involved in Genetic Predisposition to Acute Alcohol Withdrawal in Mice

1997 • 275 citations

Regional brain levels of monoamines in alcohol-preferring and -nonpreferring lines of rats

1982 • 264 citations

ANIMAL MODELS IN ALCOHOL RESEARCH

1979 • 255 citations

GENETICS OF ALCOHOLISM

1989 • 244 citations

Ethanol and acetaldehyde metabolism in rat strains genetically selected for their ethanol preference

1973 • 229 citations

Thirty-two years of selection of rats by ethanol preference: UChA and UChB strains.

1983 • 216 citations

Alcohol Taste Thresholds and Concentrations of Solution Preferred by Rats

1940 • 203 citations

Sex differences in pattern of drinking

1992 • 191 citations

The D2 Dopamine Receptor Gene

1998 • 182 citations

Rodent lines selected for factors affecting alcohol consumption.

1987 • 180 citations

Sex Differences in Alcohol Preference and Drinking Patterns Emerge during the Early Postpubertal Period in Sprague‐Dawley Rats

1996 • 165 citations

The AA and ANA rat lines, selected for differences in voluntary alcohol consumption

1989 • 153 citations

Psychopharmacology of Alcohol

1978 • 152 citations

The Determinants of Alcohol Preference in Animals

1972 • 152 citations

Short-term selective breeding as a tool for QTL mapping: ethanol preference drinking in mice.

1997 • 142 citations

Alcohol Acceptance, Preference, and Sensitivity in Mice. II. Quantitative Trait Loci Mapping Analysis Using BXD Recombinant Inbred Strains

1995 • 137 citations

Pharmacogenetics of alcohol metabolism and alcoholism

1992 • 134 citations

Genetic differences in ethanol drinking of the rat following injection of 6-OHDA, 5,6-DHT or 5,7-DHT into the cerebral ventricles

1976 • 125 citations

Drinking of high concentrations of ethanol versus palatable fluids in alcohol-preferring (P) rats: valid animal model of alcoholism

1991 • 119 citations

Mouse Strain Differences in Preference for Various Concentrations of Alcohol

1962 • 111 citations

Alcoholism and Heredity

1899 • 100 citations

Preference for alcohol evoked by tetrahydropapaveroline (THP) chronically infused in the cerebral ventricle of the rat

1977 • 98 citations

Brain regional and adrenal monoamine concentrations and behavioral responses to stress in alcohol-preferring AA and alcohol-avoiding ANA rats

1988 • 88 citations

The D2 dopamine receptor gene: A review of association studies in alcoholism

1993 • 87 citations

Quantitative trait loci (QTL) analyses and alcohol-related behaviors

1993 • 81 citations

Environmental and genetic influences on alcohol use in a volunteer sample of older twins.

1994 • 79 citations

Quantitative trait loci for ethanol sensitivity in the LS X SS recombinant inbred strains: Interval mapping

1996 • 77 citations

The genetics of alcoholisms and related disorders

1987 • 77 citations

Prenatal exposure to cocaine II: Effects on open-field activity and cognitive behavior in Sprague-Dawley rats

1992 • 74 citations

Identification of genetic markers for initial sensitivity and rapid tolerance to ethanol-induced ataxia using quantitative trait locus analysis in BXD recombinant inbred mice.

1996 • 73 citations

Preference Factors in Experimental Alcoholism

1961 • 70 citations

Alcohol as a Food

1941 • 67 citations

Differential concentration-response curves for oral ethanol self-administration in C57BL/6J and BALB/cJ mice

1987 • 65 citations

Alcohol drinking attenuated by sertraline in rats with 6-OHDA or 5,7-DHT lesions of N. accumbens: A caloric response?

1991 • 62 citations

A neuroanatomical substrate for alcohol drinking: Identification of tetrahydropapaveroline (THP)-reactive sites in the rat brain

1989 • 61 citations

A study of the effect of moderate doses of alcohol on the growth and behavior of the rat

1926 • 58 citations

Genetic aspects and risk factors in alcoholism and alcoholic liver disease

1994 • 57 citations

Alcohol, Beer and Wine as Foods

1953 • 55 citations

Reproductive state modulates ethanol intake in rats: Effects of ovariectomy, ethanol concentration, estrous cycle and pregnancy

1982 • 54 citations

Genetic aspects of alcoholism

1986 • 52 citations

Toward a definition of a valid model of alcoholism: Multiple animal models for multiple diseases

1997 • 51 citations

Sex Differences in Mesolimbic Dopamine Responses to Ethanol and Relationship to Ethanol Intake in Rats

2002 • 51 citations

Genetics of alcoholism: Simultaneous presentation of a chocolate drink diminishes alcohol preference in high drinking HAD rats

1994 • 49 citations

Gender Difference in Alcohol‐Evoked Hypothalamic‐Pituitary‐Adrenal Activity in the Rat: Ontogeny and Role of Neonatal Steroids

1996 • 47 citations

[Genetic aspects of alcoholism].

1989 • 45 citations

Comparison of the Alcohol-Preferring P Rat to the Wistar Rat in Behavioral Tests of Impulsivity and Anxiety

1998 • 41 citations

ETHANOL CONSUMPTION AND PREFERENCE IN MICE: A GENETIC ANALYSIS

1972 • 38 citations

Sex differences in schedule-induced alcohol consumption

1994 • 38 citations

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.

1994 • 37 citations

Ethyl Alcohol Consumption: Valid Measurement in Albino Rats

1968 • 36 citations

Continued Development and Unconditioned Stimulus Characterization of Selectively Bred Lines of Taste Aversion Prone and Resistant Rats

1992 • 33 citations

Ethanol intake after chronic intoxication by inhalation of ethanol vapour in rats: Behavioural dependence

1997 • 32 citations

Ethanol Preference in Strains of Rats Selectively Bred for Behavioral Characteristics

1969 • 32 citations

Effects of serotonin uptake blockers and of 5-hydroxytryptophan on the voluntary consumption of ethanol, water and solid food by UChA and UChB rats

1990 • 30 citations

Genotypic selection provides experimental confirmation for an alcohol consumption quantitative trait locus in mouse

1997 • 29 citations

Effects of ibotenic acid lesions of the ventral striatum and the medial prefrontal cortex on ethanol consumption in the rat

1995 • 28 citations

Molecular mechanisms of alcohol

1990 • 28 citations

Development of an Animal Model of Ethanol Abuse: Genetic Approach

2003 • 27 citations

Biochemical individuality; genetotrophic factors in the etiology of alcoholism.

1949 • 27 citations

Volitional consumption of ethanol by fawn-hooded rats: Effects of alternative solutions and drug treatments

1995 • 26 citations

Molecular Mechanisms of Alcohol

1989 • 26 citations

Anxiolytic Effects of Steroid Hormones during the Estrous Cycle

2002 • 26 citations

Selection of a Single Ethanol Test Solution in Free-Choice Studies with Animals

1968 • 25 citations

Alcohol Preference and Hepatic Alcohol Dehydrogenase Activity in Adult Long‐Evans Rats is Affected by Intrauterine Sibling Contiguity

1991 • 25 citations

The 5-HT1A receptor agonist 8-OH-DPAT reduces ethanol intake and maintained behavior in female Sprague-Dawley rats

1996 • 25 citations

Cyanamide given ICV or systemically to the rat alters subsequent alcohol drinking

1987 • 24 citations

Correlations of Alcohol Consumption with Related Covariates and Heritability Estimates in Older Adult Males Over a 14‐ to 18‐Year Period: The NHLBI Twin Study

1994 • 24 citations

Cork gnawing in the rat as a screening method for buspirone‐like anxiolytics

1991 • 22 citations

Initiation and maintenance of oral ethanol self-administration in female Sprague-Dawley rats

1994 • 21 citations

Ethanol preference in C57BL/6 and BALB/c mice at three ages and eight ethanol concentrations

1976 • 20 citations

Effects of estradiol benzoate and MER-25 on ethanol consumption in the ovariectomized rat.

1982 • 19 citations

Influence of Ethanol Intake on Mammary Gland Morphology and Cell Proliferation in Normal and Carcinogen‐Treated Rats

1994 • 18 citations

Prenatal Exposure to Cocaine

1998 • 17 citations

Strategies for Mapping and Identifying Quantitative Trait Loci Specifying Behavioral Responses to Alcohol

1995 • 16 citations

Alcoholism the Nutritional Approach

1973 • 15 citations

Mechanism(s) of Modulation of Alcohol Consumption: Studies on the P and NP Rats

1989 • 15 citations

Steroidal actions and voluntary drinking of ethanol by male and female rats.

1981 • 14 citations

Effects of sex steroids on ethanol pharmacokinetics and autonomic reactivity.

1981 • 14 citations

The effect of Hoe-427 (an ACTH4–9 analog) on free-choice ethanol consumption in male and female rats

1991 • 14 citations

ACETALDEHYDE METABOLISM: DIFFERENCES BETWEEN UChA AND UChB RATS

1994 • 13 citations

Sex Distinctiveness in Effective Genotype

2002 • 6 citations

Calcium channel agonist (−)-BAY k 8644 suppresses free and limited access intake of alcohol in genetic drinking rats

1999 • 5 citations

Use of artificial sweeteners to promote alcohol consumption by rats

1997 • 5 citations

Central action of an inhibitor of brain dopa-decarboxylase, NSD-1015, on cyanamide-induced alcohol drinking in rats

1990 • 5 citations

Limited Access to Ethanol in Genetic Drinking Rats Is Suppressed While Feeding Is Enhanced by the Mixed 5-HT1A Agonist/5-HT2A Antagonist FG5938

1998 • 4 citations

The Alcohol Tolerant and Alcohol Nontolerant Rat Lines Selected for Differential Sensitivity to Ethanol: A Tool to Study Mechanisms of the Actions of Ethanol

1990 • 4 citations

Biochemical Individuality

1961 • 3 citations

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