Isoforms of the Na,K-ATPase: Family members in search of function

The cadherins: cell-cell adhesion molecules controlling animal morphogenesis

1988 • 1,626 citations

Sequence and functional expression of the GABAA receptor shows a ligand-gated receptor super-family

1987 • 1,621 citations

Identification of a Family of Muscarinic Acetylcholine Receptor Genes

1987 • 1,439 citations

Effect of nerve impulses on the membrane potential of glial cells in the central nervous system of amphibia.

1966 • 1,208 citations

Cloning by functional expression of a member of the glutamate receptor family

1989 • 1,009 citations

Molecular biology of dopamine receptors

1992 • 998 citations

Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method.

1988 • 983 citations

Isozymes of the Na+/K+-ATPase

1989 • 955 citations

Existence of distinct sodium channel messenger RNAs in rat brain

1986 • 909 citations

Electrogenic sodium pump in nerve and muscle cells.

1972 • 787 citations

Identification and characterization of a ouabain-like compound from human plasma.

1991 • 759 citations

The strychnine-binding subunit of the glycine receptor shows homology with nicotinic acetylcholine receptors

1987 • 730 citations

Molecular cloning of three distinct forms of the Na+,K+-ATPase .alpha.-subunit from rat brain

1986 • 688 citations

Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin

1988 • 653 citations

A nonelectrogenic H+ pump in plasma membranes of hog stomach.

1976 • 602 citations

Two molecular forms of (Na+ + K+)-stimulated ATPase in brain. Separation, and difference in affinity for strophanthidin.

1979 • 598 citations

[35] Epitope tagging and protein surveillance

1991 • 526 citations

Molecular cloning of the rat stomach (H+ + K+)-ATPase.

1986 • 463 citations

Extracellular Potassium in the Mammalian Central Nervous System

1979 • 445 citations

Immunofluorescent localization of three Na,K-ATPase isozymes in the rat central nervous system: both neurons and glia can express more than one Na,K-ATPase

1991 • 430 citations

Structure-function relationships in the sodium-potassium ATPase .alpha. subunit: site-directed mutagenesis of glutamine-111 to arginine and asparagine-122 to aspartic acid generates a ouabain-resistant enzyme

1988 • 403 citations

The adhesion molecule on glia (AMOG) is a homologue of the beta subunit of the Na,K-ATPase.

1990 • 358 citations

The sodium pump needs its β subunit

1990 • 343 citations

Structure and Mechanism of the (Na,K)-ATPase

1981 • 321 citations

Two forms of 1B236/myelin-associated glycoprotein, a cell adhesion molecule for postnatal neural development, are produced by alternative splicing.

1987 • 320 citations

Comparison of the substrate dependence properties of the rat Na,K-ATPase alpha 1, alpha 2, and alpha 3 isoforms expressed in HeLa cells.

1991 • 308 citations

The 5HT2 receptor defines a family of structurally distinct but functionally conserved serotonin receptors.

1990 • 280 citations

Identification of a putative isoform of the Na,K-ATPase β subunit

1989 • 269 citations

Insulin induces translocation of the alpha 2 and beta 1 subunits of the Na+/K(+)-ATPase from intracellular compartments to the plasma membrane in mammalian skeletal muscle.

1992 • 259 citations

Glial cell function: Active control of extracellular K+ concentration

1972 • 233 citations

Three differentially expressed Na,K-ATPase alpha subunit isoforms: structural and functional implications.

1987 • 231 citations

Biochemical and functional characterization of a novel neuron-glia adhesion molecule that is involved in neuronal migration.

1987 • 231 citations

Mechanisms of ion transport across the choroid plexus

1972 • 230 citations

Ion Transport in Guinea Pig Cochlea:I. Potassium and Sodium Transport

1978 • 216 citations

Identification of three isozyme proteins of the catalytic subunit of the Na,K-ATPase in rat brain

1989 • 212 citations

The Peripheral nerve

1976 • 201 citations

Antisera specific for the .alpha.1, .alpha.2, .alpha.3, and .beta. subunits of the sodium-potassium ATPase: differential expression of .alpha. and .beta. subunits in rat tissue membranes

1989 • 195 citations

Cell-specific expression of mRNAs encoding Na+,K(+)-ATPase alpha- and beta-subunit isoforms within the rat central nervous system.

1991 • 193 citations

Tissue distribution of mRNAs encoding the α isoforms and β subunit of rat Na+,K+-ATPase

1987 • 178 citations

Sequence of a cDNA clone encoding the polysialic acid-rich and cytoplasmic domains of the neural cell adhesion molecule N-CAM.

1986 • 174 citations

Expression of functional (Na⁺ + K⁺)‐ATPase from cloned cDNAs

1987 • 165 citations

The 60- to 90-kDa parietal cell autoantigen associated with autoimmune gastritis is a beta subunit of the gastric H+/K(+)-ATPase (proton pump).

1990 • 159 citations

Synthesis and assembly of functional mammalian Na,K-ATPase in yeast.

1990 • 155 citations

The sodium pump : recent developments

1991 • 151 citations

Active proton secretion and potassium absorption in the rabbit outer medullary collecting duct. Functional evidence for proton-potassium-activated adenosine triphosphatase.

1989 • 143 citations

Characterization of a beta subunit of the gastric H+/K(+)-transporting ATPase.

1990 • 142 citations

Rat-brain Na,K-ATPase beta-chain gene: primary structure, tissue-specific expression, and amplification in ouabain-resistant HeLa C+ cells.

1986 • 139 citations

Multiple genes encode the human Na+,K+-ATPase catalytic subunit.

1987 • 135 citations

cDNA cloning of the beta-subunit of the rat gastric H,K-ATPase.

1990 • 134 citations

Enzymatic properties of separated isozymes of the Na,K-ATPase. Substrate affinities, kinetic cooperativity, and ion transport stoichiometry.

1985 • 127 citations

Multiple mRNAs from rat kidney and brain encode a single Na+,K+-ATPase beta subunit protein.

1987 • 126 citations

Human gastric (H+ + K+)-ATPase gene. Similarity to (Na+ + K+)-ATPase genes in exon/intron organization but difference in control region.

1990 • 124 citations

Fine specificity mapping and topography of an isozyme-specific epitope of the Na,K-ATPase catalytic subunit.

1988 • 123 citations

Tryptic and chymotryptic cleavage sites in sequence of α-subunit of (Na+ + K+)-ATPase from outer medulla of mammalian kidney

1986 • 121 citations

Neurons and astroglia express distinct subsets of Na,K-ATPase α and β subunits

1994 • 119 citations

Genes encoding alpha and beta subunits of Na,K-ATPase are located on three different chromosomes in the mouse.

1987 • 115 citations

Characterization of the Human Na,K-ATPase α2 Gene and Identification of Intragenic Restriction Fragment Length Polymorphisms

1989 • 115 citations

Tissue specificity, localization in brain, and cell-free translation of mRNA encoding the A3 isoform of Na+,K+-ATPase.

1988 • 113 citations

A nervous system-specific isotype of the beta subunit of Na+,K(+)-ATPase expressed during early development of Xenopus laevis.

1990 • 111 citations

Unique Enzymes of Purified Microsomes From Pig Fundic Mucosa

1975 • 111 citations

H-K-ATPase immunoreactivity in cortical and outer medullary collecting duct

1990 • 109 citations

Stability of Na(+)-K(+)-ATPase alpha-subunit isoforms in evolution

1990 • 109 citations

Differential expression and enzymatic properties of the Na+,K(+)-ATPase alpha 3 isoenzyme in rat pineal glands.

1990 • 106 citations

Effect of K+ ions on kinetic properties of the (Na+, K+)-ATPase (EC 3.6.1.3) of bulk isolated glial cells, perikarya and synaptosomes from rabbit brain cortex

1979 • 104 citations

The H,K-ATPase beta-subunit can act as a surrogate for the beta-subunit of Na,K-pumps.

1991 • 101 citations

Imaging voltage and synaptically activated sodium transients in cerebellar Purkinje cells

1992 • 99 citations

Differential expression of Na+,K+-ATPase alpha- and beta-subunit mRNAs in rat tissues and cell lines.

1987 • 93 citations

High-affinity ouabain binding by yeast cells expressing Na+, K(+)-ATPase alpha subunits and the gastric H+, K(+)-ATPase beta subunit.

1992 • 88 citations

Isolation and characterization of gastric microsomal glycoproteins. evidence for a glycosylated β-subunit of the H+/K−-ATPase

1990 • 87 citations

Site-directed Mutagenesis of a Conserved, Extracellular Aspartic Acid Residue Affects the Ouabain Sensitivity of Sheep Na,K-ATPase

1989 • 86 citations

Ouabain Resistance Conferred by Expression of the cDNA for a Murine Na ⁺ , K ⁺ -ATPase α Subunit

1987 • 85 citations

The Na,K-ATPase beta 2 subunit is expressed in rat brain and copurifies with Na,K-ATPase activity.

1990 • 84 citations

Cloning of the H,K-ATPase beta subunit. Tissue-specific expression, chromosomal assignment, and relationship to Na,K-ATPase beta subunits.

1990 • 81 citations

Two different Na,K-ATPases in the optic nerve: cells of origin and axonal transport.

1984 • 77 citations

The family of human Na⁺,K⁺‐ATPase genes No less than five genes and/or pseudogenes related to the α‐subunit

1987 • 76 citations

Chromosomal localization of human Na+,K+-ATPase α- and β-subunit genes

1988 • 76 citations

Family of human Na⁺,K⁺‐ATPase genes Structure of the gene for the catalytic subunit (αIII‐form) and its relationship with structural features of the protein

1988 • 70 citations

Expression of multiple Na⁺,K⁺‐ATPase genes reveals a gradient of isoforms along the nonpigmented ciliary epithelium: Functional implications in aqueous humor secretion

1991 • 64 citations

(Na+ + K+)-ATPase and plasma membrane polarity of intestinal epithelial cells: presence of a brush border antigen in the distal large intestine that is immunologically related to beta subunit.

1989 • 57 citations

Complex Expression Patterns for Na⁺,K⁺ ‐ATPase Isoforms in Retina and Optic Nerve

1990 • 57 citations

Changes of intracellular sodium and potassium ion concentrations in frog spinal motoneurons induced by repetitive synaptic stimulation

1982 • 54 citations

Ouabain as a selective agent in the isolation of somatic cell hybrids

1975 • 53 citations

The adhesion molecule on glia (AMOG) incorporated into lipid vesicles binds to subpopulations of neurons

1988 • 49 citations

Characterization of two genes for the human Na,K-ATPase β subunit

1989 • 49 citations

Expression of an ouabain-resistant Na,K-ATPase in CV-1 cells after transfection with a cDNA encoding the rat Na,K-ATPase alpha 1 subunit.

1988 • 49 citations

Vascular smooth muscle expresses a truncated Na+, K(+)-ATPase alpha-1 subunit isoform.

1991 • 46 citations

Ouabain-resistant mutants of the rat Na,K-ATPase alpha 2 isoform identified by using an episomal expression vector.

1990 • 45 citations

Co-localization and polarized distribution of Na,K-ATPase alpha 3 and beta 2 subunits in photoreceptor cells.

1991 • 41 citations

Ouabain-sensitive H+-K+ exchange mechanism in the apical membrane of guinea pig colon

1989 • 41 citations

Assignment of the gene governing cellular ouabain resistance to Mus musculus chromosome 3 using human/mouse microcell hybrids

1979 • 41 citations

Expression of mRNAs encoding α and β subunit isoforms of the Na,K-ATPase in the rat cochlea

1991 • 40 citations

The rat H+/K(+)-ATPase beta subunit gene and recognition of its control region by gastric DNA binding protein.

1991 • 40 citations

Structural organization and transcription of the mouse gastric H+, K(+)-ATPase beta subunit gene.

1991 • 38 citations

Structure of the α₁ subunit of horse Na,K‐ATPase gene

1989 • 38 citations

Na+,K+-ATPase of the photoreceptor: Selective expression of α3 and β2 isoforms

1990 • 38 citations

Functional expression of N‐terminal truncated α‐subunits of Na,K‐ATPase in Xenopus laevis oocytes

1991 • 37 citations

The mechanism of osmotic transfection of avian embryonic erythrocytes: analysis of a system for studying developmental gene expression.

1987 • 37 citations

Cytoarchitectural relationships between [3H]ouabain binding and mRNA for isoforms of the sodium pump catalytic subunit in rat brain

1991 • 34 citations

Localization of messenger RNA encoding isoforms of the catalytic subunit of the NA,K-ATPase in rat brain by in situ hybridization histochemistry

1989 • 34 citations

Molecular cloning and characterization of Na,K-ATPase from Hydra vulgaris: implications for enzyme evolution and ouabain sensitivity.

1992 • 29 citations

Identification of a cDNA clone specific for the neural cell adhesion molecule AMOG

1989 • 28 citations

Evolution of the Na,K- and H,K-ATPase β subunit gene family: Structure of the murine Na,K-ATPase β2 subunit gene

1991 • 26 citations

Chromosome-mediated transfer of the murine Na,K-ATPase alpha subunit confers ouabain resistance.

1987 • 25 citations

Assignment of Na,K-ATPase β2-subunit gene (Atpb-2) to mouse chromosome 11

1990 • 25 citations

Localization of a human Na+, K+-ATPase ? subunit gene to chromosome 19q12�q13.2 and linkage to the myotonic dystrophy locus

1988 • 25 citations

Characterization of the 5′-flanking region of the human and rat Na,K-ATPase α3 gene

1990 • 24 citations

Rat gastric H,K-ATPase β-subunit gene: Intron/exon organization, identification of multiple transcription initiation sites, and analysis of the 5′-flanking region

1991 • 23 citations

Genomic structure of the adhesion molecule on glia (AMOG, Na/K-ATPase β2 subunit)

1990 • 17 citations

Molecular cloning of the β‐subunit of the Na,K‐ATPase in the brine shrimp, Artemia

1990 • 15 citations

Developmental study of ouabain inhibition of adrenergic induction of rat pineal serotonin N-acetyltransferase (EC 2.3.1.87).

1987 • 11 citations

Characterization of the alpha +-like Na+,K+-ATPase which mediates ouabain inhibition of adrenergic induction of N-acetyltransferase (EC 2.3.1.87) activity: studies with isolated pinealocytes.

1987 • 10 citations

Functional Expression of the Genomic DNA Sequences Encoding Mouse Na,K-ATPase α1 Gene by Cotransfection of Overlapping Genomic DNA Segments

1990 • 7 citations

Genes encoding the H,K-ATPase ? and Na,K-ATPase ?3 subunits are linked on mouse Chromosome 7 and human Chromosome 19

1993 • 7 citations

Functional expression of the genomic DNA sequences encoding mouse Na,K-ATPase alpha 1 gene by cotransfection of overlapping genomic DNA segments.

1990 • 2 citations

Deleted Work

1955 • 0 citations