High Safety Factor for Action Potential Conduction Along Axons But Not Dendrites of Cultured Hippocampal and Cortical Neurons

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores

1989 • 1,616 citations

K+ channel regulation of signal propagation in dendrites of hippocampal pyramidal neurons

1997 • 1,415 citations

Co‐operative action of calcium ions in transmitter release at the neuromuscular junction

1967 • 1,326 citations

Active propagation of somatic action potentials into neocortical pyramidal cell dendrites

1994 • 1,303 citations

Activity-Dependent Action Potential Invasion and Calcium Influx into Hippocampal CA1 Dendrites

1995 • 846 citations

In vivo dendritic calcium dynamics in neocortical pyramidal neurons

1997 • 819 citations

Action potential initiation and backpropagation in neurons of the mammalian CNS

1997 • 774 citations

Calcium dependence of the rate of exocytosis in a synaptic terminal

1994 • 746 citations

Biochemical properties and subcellular distribution of an N-type calcium hannel α1 subunit

1992 • 587 citations

Characterization of single voltage‐gated Na+ and Ca2+ channels in apical dendrites of rat CA1 pyramidal neurons.

1995 • 571 citations

Calcium control of transmitter release at a cerebellar synapse

1995 • 532 citations

A fluorescent indicator for measuring cytosolic free magnesium

1989 • 527 citations

Calcium action potentials restricted to distal apical dendrites of rat neocortical pyramidal neurons

1997 • 526 citations

Facilitation and depression at single central synapses

1995 • 515 citations

Calcium entry increases the sensitivity of cerebellar Purkinje cells to applied GABA and decreases inhibitory synaptic currents

1991 • 480 citations

A model of spike initiation in neocortical pyramidal neurons

1995 • 449 citations

An evaluation of causes for unreliability of synaptic transmission.

1994 • 418 citations

The spread of Na+ spikes determines the pattern of dendritic Ca2+ entry into hippocampal neurons

1992 • 400 citations

Dendritic calcium transients evoked by single back‐propagating action potentials in rat neocortical pyramidal neurons.

1995 • 394 citations

The use of fura-2 for estimating ca buffers and ca fluxes

1995 • 364 citations

Inactivation of Presynaptic Calcium Current Contributes to Synaptic Depression at a Fast Central Synapse

1998 • 361 citations

Amplification of synaptic current by persistent sodium conductance in apical dendrite of neocortical neurons

1995 • 312 citations

Axonal Action-Potential Initiation and Na⁺Channel Densities in the Soma and Axon Initial Segment of Subicular Pyramidal Neurons

1996 • 309 citations

Ca2+ accumulations in dendrites of neocortical pyramidal neurons: An apical band and evidence for two functional compartments

1994 • 296 citations

Axonal initiation and active dendritic propagation of action potentials in substantia nigra neurons

1995 • 292 citations

Action-potential propagation gated by an axonal IA-like K+ conductance in hippocampus

1997 • 289 citations

Convergent regulation of sodium channels by protein kinase C and cAMP-dependent protein kinase

1993 • 270 citations

Slow Recovery from Inactivation of Na⁺Channels Underlies the Activity-Dependent Attenuation of Dendritic Action Potentials in Hippocampal CA1 Pyramidal Neurons

1997 • 269 citations

IPSPs modulate spike backpropagation and associated [Ca2+]i changes in the dendrites of hippocampal CA1 pyramidal neurons

1996 • 246 citations

Presynaptic failure of neuromuscular propagation in rats

1959 • 243 citations

Prolonged Sodium Channel Inactivation Contributes to Dendritic Action Potential Attenuation in Hippocampal Pyramidal Neurons

1997 • 232 citations

Spatial profile of dendritic calcium transients evoked by action potentials in rat neocortical pyramidal neurones.

1995 • 229 citations

Calcium dependence of presynaptic calcium current and post‐synaptic response at the squid giant synapse.

1986 • 218 citations

Depolarization-induced suppression of GABAergic inhibition in rat hippocampal pyramidal cells: G protein involvement in a presynaptic mechanism

1994 • 196 citations

Intermittent conduction in the spinal cord

1935 • 189 citations

Rat hippocampal neurons in culture: potassium conductances

1984 • 165 citations

Two pharmacologically and kinetically distinct transient potassium currents in cultured embryonic mouse hippocampal neurons

1992 • 150 citations

Modeling back propagating action potential in weakly excitable dendrites of neocortical pyramidal cells.

1996 • 141 citations

Fluctuations of inhibitory postsynaptic currents in Purkinje cells from rat cerebellar slices.

1996 • 140 citations

Differential flow of information into branches of a single axon

1973 • 133 citations

Retrograde signalling in depolarization‐induced suppression of inhibition in rat hippocampal CA1 cells.

1996 • 111 citations

Ca2+ Imaging of CNS Axons in Culture Indicates Reliable Coupling between Single Action Potentials and Distal Functional Release Sites

1996 • 104 citations

Glutamate toxicity in immature cortical neurons precedes development of glutamate receptor currents

1990 • 100 citations

Action potential propagation through embryonic dorsal root ganglion cells in culture. II. Decrease of conduction reliability during repetitive stimulation

1994 • 90 citations

Axonal calcium entry during fast ‘sodium’ action potentials in rat cerebellar Purkinje neurones.

1996 • 83 citations

Do nerve impulses penetrate terminal arborizations? A pre-presynaptic control mechanism

1995 • 79 citations

Modulation of brain Na+ channels by a G-protein-coupled pathway.

1994 • 75 citations

Spatial heterogeneity of intracellular Ca²⁺ signals in axons of basket cells from rat cerebellar slices

1997 • 69 citations

A Role of Intracellular Na+ in the Regulation of Synaptic Transmission and Turnover of the Vesicular Pool in Cultured Hippocampal Cells

1996 • 65 citations

Control of action potential propagation by intracellular Ca2+ in cultured rat dorsal root ganglion cells.

1996 • 57 citations

Structure and Modulation of Na⁺ and Ca²⁺ Channels

1993 • 46 citations

Modeling the attenuation and failure of action potentials in the dendrites of hippocampal neurons

1996 • 46 citations

Fluctuations in intracellular calcium responses to action potentials in single en passage presynaptic boutons of layer V neurons in neocortical slices.

1996 • 26 citations

Reliability of spike propagation in arborizations of dorsal root fibers studied by analysis of postsynaptic potentials mediated by electrotonic coupling in the frog spinal cord

1996 • 6 citations