Two distinct enzymes contribute to biphasic S6 phosphorylation in serum-stimulated chicken embryo fibroblasts.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

1977 • 5,640 citations

Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II

1988 • 1,032 citations

The effect of serum, EGF, PGF2α and insulin on S6 phosphorylation and the initiation of protein and DNA synthesis

1982 • 362 citations

A Xenopus ribosomal protein S6 kinase has two apparent kinase domains that are each similar to distinct protein kinases.

1988 • 282 citations

Identification and characterization of a mitogen-activated S6 kinase.

1988 • 223 citations

Purification and characterization of a protein kinase from Xenopus eggs highly specific for ribosomal protein S6.

1986 • 207 citations

A protein kinase from Xenopus eggs specific for ribosomal protein S6.

1985 • 195 citations

An activated S6 kinase in extracts from serum- and epidermal growth factor-stimulated Swiss 3T3 cells.

1984 • 193 citations

Sequence and expression of chicken and mouse rsk: homologs of Xenopus laevis ribosomal S6 kinase.

1989 • 174 citations

Protein phosphatase 2A inactivates the mitogen-stimulated S6 kinase from Swiss mouse 3T3 cells.

1988 • 151 citations

EGF induces biphasic S6 kinase activation: Late phase is protein kinase C-dependent and contributes to mitogenicity

1989 • 122 citations

S6 kinase in quiescent Swiss mouse 3T3 cells is activated by phosphorylation in response to serum treatment.

1988 • 118 citations

Regulation of a ribosomal protein S6 kinase activity by the Rous sarcoma virus transforming protein, serum, or phorbol ester.

1985 • 115 citations

In vivo Phosphorylation and Activation of Ribosomal Protein S6 Kinases during Xenopus Oocyte Maturation

1989 • 102 citations

Phosphorylation of ribosomal protein S6 by cAMP-dependent protein kinase and mitogen-stimulated S6 kinase differentially alters translation of globin mRNA.

1987 • 102 citations

Identification of a ribosomal protein S6 kinase regulated by transformation and growth-promoting stimuli.

1987 • 99 citations

Ordered phosphorylation of 40S ribosomal protein S6 after serum stimulation of quiescent 3T3 cells.

1983 • 97 citations

Insulin- and phorbol ester-stimulated phosphorylation of ribosomal protein S6.

1985 • 92 citations

Phosphorylation of ribosomal protein S6 in avian sarcoma virus-transformed chicken embryo fibroblasts.

1981 • 92 citations

Regulation of protein kinase activities in PC12 pheochromocytoma cells.

1986 • 88 citations

An insulin-stimulated ribosomal protein S6 kinase in 3T3-L1 cells.

1986 • 80 citations

Purification and Characterization of a 40 S Ribosomal Protein S6 Kinase from Vanadate-stimulated Swiss 3T3 Cells

1989 • 76 citations

Phorbol ester, serum, and rous sarcoma virus transforming gene product induce similar phosphorylations of ribosomal protein S6.

1984 • 76 citations

Antibodies to Xenopus egg S6 kinase II recognize S6 kinase from progesterone- and insulin-stimulated Xenopus oocytes and from proliferating chicken embryo fibroblasts.

1987 • 74 citations

Unmasking a growth factor/oncogene-activated S6 phosphorylation cascade

1989 • 73 citations

Purification of a bovine liver S6 kinase

1987 • 71 citations

Phosphorylation of ribosomal protein S6 on serine after microinjection of the Abelson murine leukemia virus tyrosine-specific protein kinase into Xenopus oocytes.

1985 • 67 citations

An S6 kinase activated during liver regeneration is related to the insulin-stimulated S6 kinase in H4 hepatoma cells.

1988 • 47 citations

Activation of a cytosolic serine protein kinase by epidermal growth factor.

1988 • 43 citations

Identification of mitogen-responsive ribosomal protein S6 kinase pp90rsk, a homolog of Xenopus S6 kinase II, in chicken embryo fibroblasts.

1990 • 42 citations

Phosphorylation sites for ribosomal S6 protein kinases in mouse 3T3 fibroblasts stimulated with platelet‐derived growth factor

1983 • 40 citations