The Central Metabolic Pathways of Escherichia coli: Relationship between Flux and Control at a Branch Point, Efficiency of Conversion to Biomass, and Excretion of Acetate

The role and control of the glyoxylate cycle in Escherichia coli

1966 • 594 citations

GLYCEROL DISSIMILATION AND ITS REGULATION IN BACTERIA

1976 • 530 citations

The Role of Energy Coupling in the Transport of β-Galactosides by Escherichia coli

1966 • 410 citations

The Effect of Carbon and Nitrogen Sources on the Level of Metabolic Intermediates in Escherichia coli

1971 • 350 citations

The Enzymic Interconversion of Acetate and Acetyl-coenzyme A in Escherichia coli

1977 • 348 citations

Biochemistry of bacterial growth

1974 • 307 citations

THE STATUS OF Y_ATP AND MAINTENANCE ENERGY AS BIOLOGICALLY INTERPRETABLE PHENOMENA

1984 • 303 citations

Bacterial lactate dehydrogenases.

1980 • 240 citations

Phosphorylation of Isocitrate Dehydrogenase of Escherichia coli

1979 • 238 citations

A protein with kinase and phosphatase activities involved in regulation of tricarboxylic acid cycle

1982 • 212 citations

The respiratory chains of Escherichia coli.

1984 • 212 citations

Phosphorylation of isocitrate dehydrogenase as a demonstration of enhanced sensitivity in covalent regulation

1983 • 192 citations

The branch point effect. Ultrasensitivity and subsensitivity to metabolic control.

1984 • 181 citations

Determination of flux through the branch point of two metabolic cycles. The tricarboxylic acid cycle and the glyoxylate shunt.

1984 • 174 citations

The control of enzyme systems in vivo: Elasticity analysis of the steady state

1983 • 170 citations

Purification and properties of phosphorylated isocitrate dehydrogenase of Escherichia coli.

1979 • 160 citations

Mechanisms and Regulation of Carbohydrate Transport in Bacteria

1986 • 154 citations

Regulation of Mammalian Pyruvate Dehydrogenase Complex by a Phosphorylation–Dephosphorylation Cycle

1981 • 153 citations

Compensatory phosphorylation of isocitrate dehydrogenase. A mechanism for adaptation to the intracellular environment.

1985 • 139 citations

Regulation of Isocitrate Dehydrogenase Activity in Escherichia coli on Adaptation to Acetate

1971 • 110 citations

Reversible Inactivation of the Isocitrate Dehydrogenase of Escherichia coli ML308 during Growth on Acetate

1975 • 89 citations

Regulation of Pyruvate Dehydrogenase from Escherichia coli

1970 • 79 citations

The regulatory properties of isocitrate dehydrogenase kinase and isocitrate dehydrogenase phosphatase from Escherichia coli ML308 and the roles of these activities in the control of isocitrate dehydrogenase

1984 • 77 citations

Regulation of Pyruvate Dehydrogenase Complex Synthesis in Escherichia coli K12. Identification of the Inducing Metabolite

1970 • 69 citations

The phosphorylation of Escherichia coli isocitrate dehydrogenase in intact cells

1984 • 67 citations

Control of the Sequential Utilization of Glucose and Fructose by Escherichia coli

1976 • 66 citations

Malic Enzyme of Escherichia coli

1969 • 65 citations

The identification of distinct protein kinases and phosphatases in the prokaryote Salmonella typhimurium.

1981 • 64 citations

The rate of turnover of the adenosine triphosphate pool of Escherichia coli growing aerobically in simple defined media

1972 • 63 citations

Allosteric controls of amphilbolic pathways in bacteria.

1970 • 58 citations

Partial purification and properties of isocitrate dehydrogenase kinase/phosphatase from Escherichia coli ML308

1984 • 53 citations

A Resolution of the Escherichia coli Pyruvate Dehydrogenase Complex

1961 • 48 citations

Isolation of active and inactive forms of isocitrate dehydrogenase from Escherichia coli ML308

1984 • 47 citations

Intermediary Metabolite Levels in Escherichia coli

1972 • 42 citations

Regulatory Characteristics of the Diphosphopyridine Nucleotide-specific Malic Enzyme of Escherichia coli

1970 • 42 citations

The reversible phosphorylation of isocitrate dehydrogenase of Salmonella typhimurium

1982 • 40 citations

Evolution of the citric acid cycle and respiratory energy conversion in prokaryotes

1981 • 35 citations

Pyruvate Metabolism and the Phosphorylation State of Isocitrate Dehydrogenase in Escherichia coli

1986 • 32 citations

Evidence suggesting that the NADPH/NADP ratio modulates the splitting of the isocitrate flux between the glyoxylic and tricarboxylic acid cycles, in Escherichia coli

1979 • 24 citations

Role of fructose‐1,6‐diphosphatase in fructose utilization by Escherichia coli

1971 • 23 citations

The role of isocitrate in control of the phosphorylation of isocitrate dehydrogenase in Escherichia coli ML308

1985 • 23 citations

Two‐dimensional analysis of proteins phosphorylated in E. coli cells

1984 • 16 citations

Control of derepressed ?-galactosidase synthesis inEscherichia coli

1974 • 6 citations