Amantadine as an additive treatment in patients suffering from drug-resistant unipolar depression.

A RATING SCALE FOR DEPRESSION

1960 • 30,921 citations

Antidepressant effects of ketamine in depressed patients

2000 • 3,482 citations

A Randomized Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Major Depression

2006 • 3,477 citations

Conceptualization and Rationale for Consensus Definitions of Terms in Major Depressive Disorder

1991 • 1,896 citations

Functional antagonists at the NMDA receptor complex exhibit antidepressant actions

1990 • 754 citations

Glutamate and Depression

2003 • 404 citations

Aminoadamantanes as NMDA receptor antagonists and antiparkinsonian agents — preclinical studies

1997 • 317 citations

The role of dopamine in the mechanism of action of antidepressant drugs

2000 • 294 citations

Reduced Brain Norepinephrine and Dopamine Release in Treatment-Refractory Depressive Illness

2000 • 291 citations

The mesolimbic dopamine system as a target for rapid antidepressant action

1997 • 209 citations

Clinical features of treatment-resistant depression.

2001 • 208 citations

Dopaminergic abnormalities in amygdaloid nuclei in major depression: a postmortem study

2002 • 176 citations

Synergistic effect of uncompetitive NMDA receptor antagonists and antidepressant drugs in the forced swimming test in rats

2002 • 173 citations

The Definition and Operational Criteria for Treatment Outcome of Major Depressive Disorder

1991 • 154 citations

Antidepressants: past, present and future

2000 • 150 citations

Dopamine and depression — Striatal dopamine D2 receptor SPECT before and after antidepressant therapy

1996 • 131 citations

Amantadine as augmentation therapy in the management of treatment-resistant depression

2003 • 100 citations

Possible Use of Amantadine in Depression

1999 • 94 citations

Adjunctive Dopamine Agonists in Treatment-Resistant Bipolar II Depression: an Open Case Series

2001 • 92 citations

The effect of CGP 37849 and CGP 39551, competitive NMDA receptor antagonists, in the forced swimming test.

1992 • 80 citations

High‐Performance Liquid Chromatographic Assay for Imipramine, Desipramine, and Their 2‐Hydroxylated Metabolites

1979 • 72 citations

A prospective test of criteria for response, remission, relapse, recovery, and recurrence in depressed patients treated with cognitive behavior therapy

1997 • 70 citations

Predictors of response to lithium augmentation in tricyclic antidepressant-resistant depression

2001 • 65 citations

Inhibitory Effect of MK-801 on Amantadine-Induced Dopamine Release in the Rat Striatum

1996 • 50 citations

Synergistic effect of imipramine and amantadine in the forced swimming test in rats. Behavioral and pharmacokinetic studies.

2004 • 41 citations

Mechanism of synergistic action following co-treatment with pramipexole and fluoxetine or sertraline in the forced swimming test in rats.

2006 • 36 citations

Repeated co-treatment with imipramine and amantadine induces hippocampal brain-derived neurotrophic factor gene expression in rats.

2007 • 30 citations

Effects of joint administration of imipramine and amantadine in patients with drug-resistant unipolar depression.

2005 • 22 citations

Effect of combined treatment with imipramine and amantadine on the central dopamine D2 and D3 receptors in rats.

2003 • 13 citations

Antidepressants given repeatedly: pharmacological evaluation of their action.

1991 • 10 citations

Declaration of Treatment Failures

1997 • 5 citations