Human Plasma all-trans-, 13-cis- and 13-cis-4-Oxoretinoic Acid Profiles during Subchronic Vitamin A Supplementation: Comparison to Retinol and Retinyl Ester Plasma Levels

Clinical pharmacokinetics; concepts and applications

1989 • 2,266 citations

Identification and spatial distribution of retinoids in the developing chick limb bud

1987 • 964 citations

Vitamin A Transport in Human Vitamin A Toxicity

1976 • 325 citations

Identification and quantitation of all-trans- and 13-cis-retinoic acid and 13-cis-4-oxoretinoic acid in human plasma.

1990 • 172 citations

All-trans-retinoic acid: measurement of reference values in human serum by high performance liquid chromatography

1982 • 153 citations

Isolation and identification of 4-hydroxy- and 4-oxoretinoic acid. In vitro metabolites of all-trans-retinoic acid in hamster trachea and liver

1979 • 126 citations

Quantification of retinoic acid by gas-liquid chromatography-mass spectrometry: total versus all-trans-retinoic acid in human plasma.

1985 • 126 citations

Recommendations for vitamin A use during pregnancy

1987 • 123 citations

Pharmacokinetics of the retinoids isotretinoin and etretinate

1982 • 117 citations

Teratogenicity and placental transfer of All-trans-, 13-cis-, 4-oxo-all-trans-, and 4-oxo-13-cis-retinoic acid after administration of a low oral dose during organogenesis in mice

1989 • 115 citations

Retinol-binding protein and the regulation of vitamin A transport.

1979 • 114 citations

13-cis-retinoic acid is an endogenous compound in human serum.

1990 • 108 citations

The biosynthesis of retinoic acid from retinol by rat tissues in vitro

1987 • 103 citations

Retinoyl β-glucuronide: an endogenous compound of human blood

1986 • 101 citations

Metabolism of all-trans-retinoic acid and all-trans-retinyl acetate. Demonstration of common physiological metabolites in rat small intestinal mucosa and circulation.

1985 • 76 citations

In vitro and in vivo metabolism of all-trans- and 13-cis-retinoic acid in hamsters. Identification of 13-cis-4-oxoretinoic acid.

1980 • 75 citations

Metabolism and Biological Activity of Vitamin A Acid in the Chick

1963 • 71 citations

Retinoic Acid: Some aspects of growth-promoting activity in the albino rat

1968 • 69 citations

Developmental effects of isotretinoin and 4‐oxo‐isotretinoin: The role of metabolism in teratogenicity

1987 • 65 citations

Retinoic acid synthesis by cytosol from the alcohol dehydrogenase negative deermouse

1989 • 61 citations

Transplacental pharmacokinetics and teratogenicity of a single dose of retinol (vitamin A) during organogenesis in the mouse

1989 • 56 citations

Pharmacokinetics of isotretinoin and its major blood metabolite following a single oral dose to man

1983 • 50 citations

Vitamin A supplementation increases levels of retinoic acid compounds in human plasma: possible implications for teratogenesis

1990 • 39 citations

Characterization of oxidized and glucuronidated metabolites of retinol in monkey plasma by thermospray liquid chromatography/mass spectrometry

1990 • 37 citations

A New Vaginal Smear Assay for Vitamin A in Rats

1982 • 37 citations

Recent progress in vitamin A research: nuclear retinoic acid receptors and their interaction with gene elements

1990 • 36 citations

Characterization of retinyl beta-glucuronide in human blood

1989 • 34 citations

Analysis of 5-(4-acetamidophenyl)pyrazin-2(1H)-one (SK&F 94120) in plasma with an analytichem automated sample processor liquid chromatography module

1986 • 27 citations

Absorption of Retinol and Retinyl Esters via Lymph and the Portal Vein in the Rat

1972 • 16 citations

The biological activity of cyclopropyl analogs of all-trans- And 13-cis-retinoic acid in the rat vaginal smear assay

1985 • 9 citations