Lithium and the Cell

Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands

1982 • 2,148 citations

The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain.

1980 • 1,099 citations

Cell membrane receptors for drugs and hormones: A multidisciplinary approach

1979 • 850 citations

Rapid mobilization of Ca2+ from rat insulinoma microsomes by inositol-1,4,5-trisphosphate

1984 • 410 citations

Mechanisms of Membrane-Receptor Regulation

1984 • 335 citations

Is phosphatidic acid a calcium ionophore under neurohumoral control?

1980 • 331 citations

Reduced Brain Inositol in Lithium-treated Rats

1971 • 309 citations

The red cell.

1972 • 306 citations

Cell membrane receptors for drugs and hormones : a multidisciplinary approach

1978 • 282 citations

Evidence that Lithium Alters Phosphoinositide Metabolism: Chronic Administration Elevates Primarily <scp>d</scp>‐myo‐Inositol‐1‐Phosphate in Cerebral Cortex of the Rat

1981 • 273 citations

Proposed mechanism of cholinergic action in smooth muscle

1980 • 256 citations

The permeability of frog muscle fibres to lithium ions

1959 • 246 citations

Requirement of Thymus-dependent Lymphocytes for Potentiation by Adjuvants of Antibody Formation

1971 • 245 citations

Lithium in Medical Practice.

1978 • 243 citations

Intracellular lithium concentration and clinical response: Towards a membrane theory of depression

1973 • 237 citations

The Concentration Dependence of Active Potassium Transport in the Human Red Blood Cell*

1967 • 206 citations

OSTEOGENESIS IMPERFECTA

1976 • 189 citations

Coupling of lithium to sodium transport in human red cells

1975 • 174 citations

Basic Mechanisms in the Action of Lithium

1983 • 172 citations

Studies on the lithium transport across the red cell membrane

1976 • 165 citations

Lithium research and therapy

1975 • 158 citations

Recent hypotheses regarding the phosphatidylinositol effect

1981 • 156 citations

Lithium, membranes, and manic-depressive illness

1980 • 156 citations

Influence of Lithium Ions on the Transmembrane Potential and Cation Content of Cardiac Cells

1964 • 135 citations

Kinetics and stoichiometry of Na-dependent Li transport in human red blood cells.

1978 • 134 citations

Effects of bicarbonate on lithium transport in human red cells.

1978 • 129 citations

Lithium inhibition of adrenaline-stimulated adenylate cyclase in humans

1976 • 127 citations

Histamine Stimulation of Inositol 1‐Phosphate Accumulation in Lithium‐Treated Slices from Regions of Guinea Pig Brain

1984 • 116 citations

CONFORMATION AND MOLECULAR MECHANISMS OF CARRIERS AND CHANNELS^fn1

1975 • 110 citations

Studies on the Activc Transport of Lithium in the Isolated Frog Skin

1955 • 109 citations

Receptors, adenylate cyclase, depression, and lithium.

1981 • 102 citations

Lithium in Medical Practice

1979 • 95 citations

Effects of Some Monovalent Anions on Fluxes of Na and K, and on Glucose Metabolism of Ouabain Treated Human Red Cells

1967 • 91 citations

Studies on lithium transport across the red cell membrane

1979 • 76 citations

Abnormal lithium and sodium transport in erythrocytes of a manic patient and some members of his family

1977 • 76 citations

A heritable disorder of lithium transport in erythrocytes of a subpopulation of manic-depressive patients

1978 • 75 citations

Studies on the lithium transport across the red cell membrane

1977 • 75 citations

The determination of picogram levels of 5‐HT in biological fluids

1976 • 73 citations

Mechanisms of Receptor Regulation

1985 • 70 citations

Renal Excretion of Cation in the Dog During Infusion of Isotonic Solutions of Lithium Chloride

1952 • 67 citations

Lithium efflux through the Na/K pump in human erythrocytes

1977 • 67 citations

Studies on the lithium transport across the red cell membrane

1977 • 67 citations

Inositol phospholipids and neurotransmitter-receptor signalling mechanisms

1983 • 66 citations

Regulation of phosphatidate synthesis by secretagogues in parotid acinar cells

1982 • 64 citations

INCREASED LITHIUM ERYTHROCYTE/ PLASMA RATIO IN MANIC-DEPRESSIVE PSYCHOSIS

1973 • 60 citations

Lithium Research and Therapy

1976 • 58 citations

Lithium and water metabolism

1975 • 57 citations

Highly Excited Atoms

1981 • 57 citations

Lithium fluxes in human erythrocytes

1979 • 55 citations

THE EFFECT OF LITHIUM TREATMENT ON ERYTHROCYTE MEMBRANE ATPase ACTIVITIES AND ERYTHROCYTE ION CONTENT

1978 • 55 citations

Lithium therapy and erythrocyte membrane cation carrier

1974 • 54 citations

Interindividual differences in the Na+-dependent Li+ countertransport system and in the Li+ distribution ratio across the red cell membrane among Li+-treated patients

1977 • 52 citations

Effects of Monovalent Cations on Sodium Permeability of Human Red Cells

1970 • 52 citations

Lithium Ion Transport and Affective Disorders Within Families of Bipolar Patients

1983 • 52 citations

Binding constants of Li+, K+, and Tl+ in the gramicidin channel determined from water permeability measurements

1981 • 51 citations

The Dual Effect of Lithium Ions on Sodium Efflux in Skeletal Muscle

1968 • 49 citations

Effect of lithium on the physostigmine-induced behavioral syndrome and plasma cyclic GMP

1979 • 48 citations

Receptors, antibodies, and disease.

1984 • 47 citations

LITHIUM TREATMENT STRONGLY INHIBITS CHOLINE TRANSPORT IN HUMAN ERYTHROCYTES

1974 • 47 citations

Cationic selectivity and competition at the sodium entry site in frog skin.

1980 • 47 citations

Induction by lithium ion of multiplication of mouse mammary epithelium in culture.

1979 • 46 citations

AN IRREVERSIBLE EFFECT OF LITHIUM ADMINISTRATION TO PATIENTS

1976 • 46 citations

Perturbation of Sodium-Lithium Countertransport in Red Cells

1983 • 44 citations

THE EFFECT OF LITHIUM ON THE ELECTROCARDIOGRAM OF ANIMALS AND RELATION OF THIS EFFECT TO THE RATIO OF THE INTRACELLULAR AND EXTRACELLULAR CONCENTRATIONS OF POTASSIUM

1954 • 44 citations

Excretion and Distribution of Lithium in the Dog

1951 • 43 citations

The effects of lithium on the permeability of an epithelial membrane, the toad urinary bladder

1972 • 43 citations

Movement of lithium across toad urinary bladder

1971 • 43 citations

Growth effects of lithium chloride in BALB/c 3T3 fibroblasts and madin-darby canine kidney epithelial cells

1981 • 43 citations

Concentration of Lithium, Sodium and Potassium in Epithelial Cells of the Isolated Frog Skin during Active Transport of Lithium

1964 • 42 citations

Lithium and rubidium interactions with sodium- and potassium-dependent adenosine triphosphatase: a molecular basis for the pharmacological actions of these ions.

1974 • 42 citations

Growth effect of lithium on mouse mammary epithelial cells in serum‐free collagen gel culture

1983 • 42 citations

Lithium and Mania

1981 • 41 citations

Initiation of DNA synthesis in mammary epithelium and mammary tumors by lithium ions

1980 • 40 citations

Na+/L+ selectivity in transport systemA: Effects of substrate structure

1977 • 40 citations

Inhibition of lithium transport across toad bladder by amiloride

1972 • 40 citations

Effects of lithium on angiotensin‐stimulated phosphatidylinositol turnover and aldosterone production in adrenal glomerulosa cells: a possible causal relationship

1984 • 40 citations

Beneficial Effect of Oral Lithium Carbonate in the Treatment of Pancreatic Cholera Syndrome

1980 • 39 citations

Effect of lithium on the rate of protein synthesis in the sea urchin embryo

1968 • 39 citations

Inhibition of Epidermal Adenyl Cyclase by Lithium Carbonate

1981 • 37 citations

Mechanisms by which Li+ stimulates the (Na++K+)-dependent ATPase

1975 • 33 citations

Sodium-calcium exchange in mammalian myocardium: the effects of lithium

1980 • 33 citations

Stimulation of the Sodium Pump in the Red Blood Cell by Lithium and Potassium

1972 • 30 citations

Li+ stimulation of ouabain-sensitive respiration and (Na+-K+)-ATPase of kidney cortex of ground squirrels

1970 • 29 citations

Lithium Transport Across the RBC Membrane

1980 • 29 citations

Further evidence for a potassium‐like action of lithium ions on sodium efflux in frog skeletal muscle

1972 • 28 citations

Lithium transport across isolated frog skin epithelium

1975 • 28 citations

Effects of Bicarbonate and Thiocyanate on Fluxes of Na and K, and on Glucose Metabolism of Actively Transporting Human Red Cells

1969 • 28 citations

Transport of lithium and rectification by frog skin

1973 • 27 citations

Effects of lithium, and lithium and alcohol administration on (NA + K)-ATPase

1981 • 26 citations

Chronic lithium prevents reserpine-induced supersensitivity of adenylate cyclase

1980 • 26 citations

Increased erythrocyte Na+ pump and NaK-ATPase activity during lithium therapy.

1976 • 25 citations

Elevation of choline and glycine in red blood cells of psychiatric patients due to lithium treatment.

1981 • 25 citations

Studies on lithium transport across the red cell membrane

1979 • 24 citations

An Effect of Anions on Transfer of Sodium Through the Human Red Cell Membrane

1965 • 24 citations

Effect of growth in lithium on ouabain binding, Na‐K‐ATPase and Na and K transport in hela cells.

1975 • 24 citations

Cation inhibition of DNA synthesis in mammary epithelial cells in vitro

1968 • 23 citations

The influence of external sodium and potassium on lithium uptake by primary brain cell cultures at ?therapeutic? lithium concentration

1980 • 23 citations

Mechanism of lithium-induced elevation in red blood cell choline content: an in vitro analysis.

1980 • 22 citations

Über die elektromotorischen Kräfte, welche an der Oberfläche tierischer Membranen bei der Berührung mit verschiedenen Elektrolyten zustande kommen

1904 • 22 citations

Lithium ion accumulation by cultured glioma cells

1979 • 22 citations

Blood Pressure and Sodium-lithium Countertransport: Findings in Population-based Surveys

1984 • 21 citations

The Effect of Li on the Glucagon‐Sensitive Adenylate Cyclase in Vivo in Man

1977 • 21 citations

Kinetics of lithium efflux through the (Na,K)-pump of human erythrocytes

1980 • 20 citations

A mechanism for the accumulation of choline in erythrocytes during treatment with lithium.

1980 • 20 citations

Prediction of the lithium ratio in man by means of an in vitro test

1977 • 20 citations

Thyrotropin-releasing hormone stimulates inositol phosphate production in normal anterior pituitary cells and GH3 tumour cells in the presence of lithium

1983 • 19 citations

Lithium's inhibition of erythrocyte cation countertransport involves a slow process in the erythrocyte

1983 • 18 citations

Lithium ratio and maintenance treatment response

1982 • 17 citations

A study of Li+-selective permeation through lipid bilayer membranes mediated by a new ionophore (AS701)

1981 • 17 citations

Receptors, antibodies and disease

1983 • 16 citations

Influence of Lithium on Cyclic AMP Accumulation in Isolated Rat Fat Cells

1979 • 16 citations

Effects of lithium and thallous ions on sodium pump activity in the guinea-pig heart and their relationship to the positive inotropic action

1978 • 15 citations

Effect of lithium and thiocyanate on the nucleic acid-synthesis of tetrahymena

1970 • 14 citations

Reduced plasma cyclic AMP level during prophylactic lithium treatment in patients with affective disorders.

1980 • 13 citations

On the Mechanism of Inhibition of Rat Fat Cell Adenylate Cyclase by Lithium

1981 • 13 citations

Elevation of erythrocyte glycine levels during lithium treatment of affective disorders

1982 • 12 citations

Transmembrane distribution of lithium and sodium in erythrocytes of depressed patients

1980 • 11 citations

The effect of lithium on rat erythrocyte choline, glycine and glutathione levels

1983 • 11 citations

A tracer method to study unidirectional fluxes of lithium

1980 • 11 citations

Mechanism of epithelial lithium transport. Evidence for basolateral Na:Na and Na:Li exchange.

1983 • 11 citations

Lithium Pharmacokinetics, Duration of Therapy, and the Adenylate Cyclase System

1982 • 11 citations

Effect of Lithium Ingestion on Water and Electrolyte Transport in Rat Intestine

1981 • 11 citations

Pharmacology—Lithium Absorption, Distribution, Renal Handling, and Effect on Body Electrolytes

1973 • 10 citations

Cellular uptake of lithium via amino acid transport system A

1978 • 10 citations

Effects of lithium and cesium salts on sarcoma-I implants in the mouse.

1979 • 10 citations

Transients in toad skin: Short circuit current and ionic fluxes related to inner sodium substitution by monovalent cations

1978 • 10 citations

Lithium ratio in psychiatric patients: A caveat

1983 • 10 citations

The effect of lithium on the transport of sodium, potassium and chloride by the colon of normal and sodium‐depleted rats.

1976 • 10 citations

Cellular Li+ opens paracellular path in toad skin: Amiloride blockable effect

1983 • 9 citations

Effect of lithium treatment on microsomal ATPase activity in several tissues

1973 • 9 citations

Does protein synthesis decline in lithium-treated sea urchin embryos because RNA synthesis is inhibited?

1982 • 9 citations

Dissociation by Lithium of Hormone‐induced Formation of Cyclic AMP and Release of Glycerol in Isolated Rat Fat Cells

1980 • 6 citations

Lithium transport by the colon of normal and sodium‐depleted rats.

1976 • 6 citations

Influence of lithium on mammary tumor growth in vivo

1980 • 5 citations

Effect of Li and of other ions on Na transport in epithelial cells of frog skin

1980 • 5 citations

Effect of Lithium Ions on RNA Synthesis in Mammary Gland Explants of Mice

1975 • 4 citations

Plasma Cyclic AMP Hyper-Response to Glucagon in Manic Patients on Lithium Treatment

1981 • 3 citations

Plasma and Urinary Cyclic AMP Levels in Normal and Lithium‐treated Rats

1977 • 3 citations

Plasma and Urinary Cyclic AMP Levels in Normal and Lithium‐treated Rats

1977 • 3 citations

Lithium and the heart.

1982 • 2 citations

Deleted Work

1955 • 0 citations